A directory of core research facilities, services, and instrumentation in Rhode Island

Instrument/Service



Facility Instrument/Services Manufacturer/Description Functions
3D Facility for Biomedical Sciences: Animation, Visualization and Printing
The University of Rhode Island
3D Printer

Z650 3D System/Z-corpProduces realistic color (Powder Based) models without paint to better evaluate the look, feel, and style of product designs. Five print heads provide the widest range of accurate colors, including true black and improved color consistency from part to part. 3D print text labels or images can be directly applied onto printed models.
Benedum Stable Isotope Facility
Brown University
Mass Spectrometer, Isotope Ratio

ThermoFisher (Finnigan) MAT 252 dual inlet Isotope Ratio Mass Spectrometer with automated sample reaction device for up to 48 samples and with Kiel III Carbonate interface.Instrument primarily dedicated to the measurement of the stable isotopes of carbon and oxygen on inorganic carbonates. The facility accommodates projects both internal and external to Brown including analysis of terrestrial and marine material. The vast majority of samples analyzed are funded through external grants but I also facilitate a significant number of small unfunded, exploratory, analyses to help construct proof-of-concept data sets in preparation for proposals.
Bioinformatics Core
The University of Rhode Island
Bioinformatics Analysis

Service Service to provide bioinformatics consultation, education, and training
Bioinformatics Facility
Brown University
Bioinformatics Analysis

ServiceService to provide technical assistance and training in bioinformatics
Bioinformatics Facility
Brown University
Bioinformatics Analysis - Ingenuity Pathway Analysis (IPA)

Software: Ingenuity Pathway Analysis (IPA)Software for network analysis
Brown University Herbarium
Brown University
Herbarium

Dried and pressed plant specimens mounted on sheets of archival paper. Plant data.The collection includes around 100,000 plant specimens and is an important depository of Rhode Island and New England collections. It is also rich in western and southern North American plants and includes special sets of historically valuable specimens from 19th and early 20th century western US expeditions. Among other important collections, the herbarium also includes a full set of Charles Wright's Cuban plants (1856-1867) and a unique and classic collection of Carex
Bryant Unistructure Science Spaces
Bryant University
Gas Chromatograph - Mass Spectrometer (GC - MS)

Contact: Julia Crowley-Parmentier

Agilent Technologies 7890A GC and 5975C MSDAnalyze for volatile organics; pyrolysis; MSD and FID
Bryant Unistructure Science Spaces
Bryant University
Sample Concentrator, Purge & Trap

Contact: Julia Crowley-Parmentier

Teledyne Tekmar velocity XPT sample concentrator and AQUATek 70 vial autosampleranalyze for highly volatile organics; accessory for the GC-MS
Bryant Unistructure Science Spaces
Bryant University
High Performance Liquid Chromatography (HPLC)

Contact: Julia Crowley-Parmentier

ShumatzuAnalyze for non-volatile organics
Bryant Unistructure Science Spaces
Bryant University
Spectrometer

Contact: Julia Crowley-Parmentier

Agilent Technologies 7700 series Inductive Coupling Plasma Mass Spectrometer( ICP-MS) with ASX-500 series autosamplerAnalyze for trace elements
Bryant Unistructure Science Spaces
Bryant University
Solvent Extractor

Contact: Julia Crowley-Parmentier

Dionex ASE 350 Accelerated Solvent Extractor (ASE)Accelerated extractions
Bryant Unistructure Science Spaces
Bryant University
Concentrator Worstation

Contact: Julia Crowley-Parmentier

Caliper LifeSciences Turbo Vap LV Concentration WorkstationConcentrator
Bryant Unistructure Science Spaces
Bryant University
Freeze Dry System

Contact: Julia Crowley-Parmentier

Labconco FreeZone 4.5Freeze dryer
Bryant Unistructure Science Spaces
Bryant University
Spectrophotometer

Contact: Julia Crowley-Parmentier

Shimadzu UV 2600UV/Vis spectrophotometer for quantifying concentrations
Bryant Unistructure Science Spaces
Bryant University
Spectrophotometer

Thermo Scientific AquaMate PlusUV/Vis spectrophotometer for quantifying concentrations
Bryant Unistructure Science Spaces
Bryant University
Microscope - Electron

Contact: Julia Crowley-Parmentier

JEOL JSM 6010LA Scanning Electron Microscope (SEM)Scanning electron microscope with EDS
Bryant Unistructure Science Spaces
Bryant University
Critical Point Dryer

Contact: Julia Crowley-Parmentier

Tousimis Sandri-PVT-3D Critical Point Dryer (CPD)Maintain structural integrity for soft tissue use of the SEM
Bryant Unistructure Science Spaces
Bryant University
Sputter Coater System

Contact: Julia Crowley-Parmentier

Denton Vacuum Desk V gold sputter coater and carbon coaterCoat non-conducting samples with gold or carbon for use on the SEM
Bryant Unistructure Science Spaces
Bryant University
Microscope

Contact: Julia Crowley-Parmentier

Zeiss A1 AXIO Polarized Light Microscope and Q imaging RETIGA 400R ImagerRecordable polarized light imaging
Bryant Unistructure Science Spaces
Bryant University
Microscope

Contact: Julia Crowley-Parmentier

Zeiss Axiovert 40CFL Inverted MicroscopeRecordable inverted microscopy
Bryant Unistructure Science Spaces
Bryant University
Microscope

Contact: Julia Crowley-Parmentier

Zeiss Primo Star with AxioCamRecordable imaging
Bryant Unistructure Science Spaces
Bryant University
Anaerobic Chamber

Contact: Julia Crowley-Parmentier

Microbiology International Whitley DG250 Anaerobic WorkstationSimulate anoxic environments for anaerobic work
Bryant Unistructure Science Spaces
Bryant University
Anaerobic Chamber

Contact: Julia Crowley-Parmentier

MBRAUN Labstar Anaerobic Glovebox Workstationsimulate anoxic environments for anaerobic work
Bryant Unistructure Science Spaces
Bryant University
PCR Thermal Cycler

Contact: Julia Crowley-Parmentier

Bio-Rad PCR Thermocycler C1000 Touch; Fraction Collector model 2110DNA amplifier
Bryant Unistructure Science Spaces
Bryant University
Biological Safety Cabinet

Contact: Julia Crowley-Parmentier

LABGARD ES class II, type A2 Biological Safety CabinetMaintain sterility and contain infectious work
Bryant Unistructure Science Spaces
Bryant University
Freezer

Contact: Julia Crowley-Parmentier

Thermo Scientific Isotemp Basic U86-13A41 minus 70 degree freezerLong term storage of biological specimens
CCRI Biology Labs
Community College of Rhode Island
Autoclave

Consolidated Stills & Sterilizers 24D36Sterilization. Chamber size is 24inch x36inch, Volume 9.4 cu. Ft
CCRI Biology Labs
Community College of Rhode Island
Balance - Analytical

Orion Analytical Balance Weight determination with capacity of 60g.
CCRI Biology Labs
Community College of Rhode Island
Balance - Top Loading

EK-I Compact Balance Weight determination (2 units)
CCRI Biology Labs
Community College of Rhode Island
Incubator

Fisher Scientific Isotemp Digital & Analog Dry Bath IncubatorProvide controlled dry heat environment for clinical & general chemistry applications
CCRI Biology Labs
Community College of Rhode Island
Electrophoresis System

Bio-Rad Mini-Protean Tetra Cell, Vertical protein electrophoresis gel boxesRunning Protein or DNA polyacrylamide gels
CCRI Biology Labs
Community College of Rhode Island
Microscope

Lieder MI-500 Series Compound Inverted MicroscopeTissue Culture
CCRI Biology Labs
Community College of Rhode Island
pH Meter

Thermo Scientific Orion 2-Star Bench Top pH MeterGeneral purpose measurements
CCRI Biology Labs
Community College of Rhode Island
Blotting System, Semi-Dry

Shelton Scientific Semi-Dry Blotting SystemTransfer of protein, RNA & DNA gels to a solid membrane support for visualization, 24cmx30cm.
CCRI Biology Labs
Community College of Rhode Island
Spectrophotometer

Thermo Scientific Genesis 20 Visible SpectrophotometerUV spectrophotometer for quantifying concentrations
CCRI Biology Labs
Community College of Rhode Island
Transilluminator

FOTODYNE Foto Phoresis UV TransilluminatorImaging-protein gel analysis, GFP Analysis
CCRI Biology Labs
Community College of Rhode Island
Incubator - Shaker

Lab Companion IS-971 Floor Model Incubator Shaker Growing of bacteria, 250 L chamber
CCRI Biology Labs
Community College of Rhode Island
Biological Safety Cabinet

NuAire Class II Type A2Maintain sterility and contain infectious work
Center for Computation and Visualization
Brown University
High Performance Computing Cluster

IBM idataPlex High Performance Computing ClusterCenter for Computation and Visualization (CCV): HPC cycles, Storage, backups, Visualization, data management implementations, server colocation, scientific support
Centralized Research Core Facility
The University of Rhode Island
Analyzer - Clinical Chemistry

Contact: Kim Andrews, B.A.

Randox RX Daytona Chemistry AnalyzerClinical chemistry analyzer
Centralized Research Core Facility
The University of Rhode Island
Analyzer - Live Cell

Contact: Kim Andrews, B.A.

Roche xCELLigence Real-Time Cell Analysis SystemLabel free live cell analyzer
Centralized Research Core Facility
The University of Rhode Island
Biological Safety Cabinet

Contact: Kim Andrews, B.A.

NuAire, Laminar Flow HoodCell culture facility
Centralized Research Core Facility
The University of Rhode Island
Cell Counter

Contact: Kim Andrews, B.A.

Nexcellom Cellometer Vision Cell CounterAutomated cell counter
Centralized Research Core Facility
The University of Rhode Island
Centrifuge

Contact: Kim Andrews, B.A.

Sorvall Evolution High Speed CentrifugeHigh speed centrifuge
Centralized Research Core Facility
The University of Rhode Island
Centrifuge

Contact: Kim Andrews, B.A.

Thermo MultiFuge Centrifuge table-topCentrifuge
Centralized Research Core Facility
The University of Rhode Island
Centrifuge - Ultra

Contact: Kim Andrews, B.A.

Beckman Coulter Optima Ultra centrifuge
Centralized Research Core Facility
The University of Rhode Island
Centrifuge - Ultra

Contact: Kim Andrews, B.A.

Sorvall Micro Ultra CentrifugeUltra centrifuge
Centralized Research Core Facility
The University of Rhode Island
Evaporator

Contact: Kim Andrews, B.A.

Buchi RotaVap SystemRotary evaporator
Centralized Research Core Facility
The University of Rhode Island
Fluorescence Activated Cell Sorter (FACS)

Contact: Kim Andrews, B.A.

Becton Dickinson (BD) Biosciences FACS Verse Flow cytometerFACS
Centralized Research Core Facility
The University of Rhode Island
Freeze Dry System

Contact: Kim Andrews, B.A.

Labconco 12L Freeze dryerFreeze dryer
Centralized Research Core Facility
The University of Rhode Island
Gel Electrophoresis

Contact: Kim Andrews, B.A.

Agilent Offgel Fractionator 3100Liquid phase Isoelectric Focusing (IEF) System
Centralized Research Core Facility
The University of Rhode Island
Gel Electrophoresis

Contact: Kim Andrews, B.A.

Bio-Rad 2D Gel SystemTwo Dimensional (2D) Gel Electrophoresis
Centralized Research Core Facility
The University of Rhode Island
Gel Electrophoresis

Contact: Kim Andrews, B.A.

Bio-Rad PAGE Electrophoresis SystemOne Dimensional (1D) Gel Electrophoresis
Centralized Research Core Facility
The University of Rhode Island
High Performance Liquid Chromatography - Ultra High (UHPLC)

Contact: Kim Andrews, B.A.

Hitachi UPLC SystemUPLC
Centralized Research Core Facility
The University of Rhode Island
High Performance Liquid Chromatography (HPLC)

Contact: Kim Andrews, B.A.

GE AKTA Fast Protein Liquid Chromatograph (FPLC)FPLC
Centralized Research Core Facility
The University of Rhode Island
High Performance Liquid Chromatography (HPLC)

Contact: Kim Andrews, B.A.

Hitachi Analytical HPLCHPLC
Centralized Research Core Facility
The University of Rhode Island
High Performance Liquid Chromatography (HPLC)

Contact: Kim Andrews, B.A.

Hitachi Prep-HPLC SystemHPLC
Centralized Research Core Facility
The University of Rhode Island
High Performance Liquid Chromatography (HPLC)

Contact: Kim Andrews, B.A.

Teledyne-ISCO CombiFlash SystemFlash
Centralized Research Core Facility
The University of Rhode Island
Imaging System - Animal

Contact: Kim Andrews, B.A.

Caliper/PE IVIS Lumina Whole Animal ImagerWhole animal imager
Centralized Research Core Facility
The University of Rhode Island
Imaging System - Gel Imager

Contact: Kim Andrews, B.A.

GE Imagescanner II Gel imager
Centralized Research Core Facility
The University of Rhode Island
Imaging System - Gel Imager

Contact: Kim Andrews, B.A.

GE Typhoon FLA 9000 Multimode ImagerGel imager
Centralized Research Core Facility
The University of Rhode Island
Imaging System - Gel Imager

Contact: Kim Andrews, B.A.

Li-Cor Odyssey IR ImagerIR gel imager
Centralized Research Core Facility
The University of Rhode Island
Imaging System - Microarray

Contact: Kim Andrews, B.A.

Agilent DNA Microarray ScannerDNA array
Centralized Research Core Facility
The University of Rhode Island
Liquid Chromatography - Mass Spectrometer (LC - MS)

Contact: Kim Andrews, B.A.

AB Sciex QSTAR LC/MS SystemESI-TOF MS
Centralized Research Core Facility
The University of Rhode Island
Mass Spectrometer

Contact: Kim Andrews, B.A.

Shimazu Axima MALDI-TOF MS/MSMALDI MS
Centralized Research Core Facility
The University of Rhode Island
Mass Spectrometer

Contact: Kim Andrews, B.A.

Thermo iCAPQ-a ICP-MSElemental Analyzer
Centralized Research Core Facility
The University of Rhode Island
Microplate Reader

Contact: Kim Andrews, B.A.

BMG LabTech Microplate ReaderFluorescence/UV/VIS
Centralized Research Core Facility
The University of Rhode Island
Microplate Reader

Contact: Kim Andrews, B.A.

Molecular Devices SpectraMax M2 Fluorescence/UV/VIS
Centralized Research Core Facility
The University of Rhode Island
Microplate Reader

Contact: Kim Andrews, B.A.

Promega GlowMax SystemChemiluminescence
Centralized Research Core Facility
The University of Rhode Island
Microscope

Contact: Kim Andrews, B.A.

Nikon Eclipse E600 Upright MicroscopeMicroscope
Centralized Research Core Facility
The University of Rhode Island
Microscope

Contact: Kim Andrews, B.A.

Nikon TE2000E /C2 Inverted Confocal Confocal Microscope
Centralized Research Core Facility
The University of Rhode Island
PCR Thermal Cycler

Contact: Kim Andrews, B.A.

Applied Biosystems/Life Technologies ABI Vii7- RT-PCRRT-PCR
Centralized Research Core Facility
The University of Rhode Island
PCR Thermal Cycler

Contact: Kim Andrews, B.A.

Eppendorf Mastercycler PCRPCR
Centralized Research Core Facility
The University of Rhode Island
Protein Sequencer

Contact: Kim Andrews, B.A.

Applied Biosystems Procise 491 Protein SequencerN-terminal protein sequencer
Centralized Research Core Facility
The University of Rhode Island
Robotic Workstation - Liquid Handler

Contact: Kim Andrews, B.A.

BioTek Precision XS Sample ProcessorSample processor
Centralized Research Core Facility
The University of Rhode Island
Robotic Workstation - RNA/DNA

Contact: Kim Andrews, B.A.

Fuji Film DNA/RNA Isolation SystemDNA/RNA isolation
Centralized Research Core Facility
The University of Rhode Island
Scintillation Counter

Contact: Kim Andrews, B.A.

PerkinElmer Microbeta1450 Scintillation CounterScintillation counter
Centralized Research Core Facility
The University of Rhode Island
Scintillation Counter

Contact: Kim Andrews, B.A.

PerkinElmer Wizard 1470 Gamma CounterGamma counter
Centralized Research Core Facility
The University of Rhode Island
Spectrometer

Contact: Kim Andrews, B.A.

PerkinElmer Luminescence Spectrometer LS55Fluorescence
Centralized Research Core Facility
The University of Rhode Island
Spectrometer

Contact: Kim Andrews, B.A.

Jasco 810 Circular Dichroism (CD) SpectropolarimeterCD
Centralized Research Core Facility
The University of Rhode Island
Spectrometer

Contact: Kim Andrews, B.A.

Thermo Nicolet 380 Fourier Transformed Infrared Spectrometer (FT-IR)FT-IR
Centralized Research Core Facility
The University of Rhode Island
Spectrophotometer

Contact: Kim Andrews, B.A.

Beckman UV/VIS DU800UV/VIS
Centralized Research Core Facility
The University of Rhode Island
Spectrophotometer

Contact: Kim Andrews, B.A.

Thermo Scientific NanoDrop 3300UV/VIS
Centralized Research Core Facility
The University of Rhode Island
Spectrophotometer

Contact: Kim Andrews, B.A.

Thermo Scientific NanoDropUV/VIS
Centralized Research Core Facility
The University of Rhode Island
Transfection Platform

Contact: Kim Andrews, B.A.

Lonza Nucleofactor SystemHigh-throughput transfection
Centralized Research Core Facility
The University of Rhode Island
Water Purification System - Deionized (DI)

Contact: Kim Andrews, B.A.

Millipore Milli-Q Water SystemDI water System
Centralized Research Core Facility
The University of Rhode Island
Western Blotting System

Contact: Kim Andrews, B.A.

Bio-Rad Turbo Trans Blot system Western Blotting
Centralized Research Core Facility
The University of Rhode Island
Western Blotting System

Contact: Kim Andrews, B.A.

Life Technologies BenchPro Western SystemWestern Blotting processor
Centralized Research Core Facility
The University of Rhode Island
Western Blotting System

Contact: Kim Andrews, B.A.

Protein Simple Simon WesternLiquid phase Western Blotting
Core Research Laboratories
Lifespan-Rhode Island Hospital
Cryostat

Contact: Paul Monfils

Reichert-Jung Cryocut 1800Frozen tissue sectioning (used with Superfrost/Plus microscope slides (approximately 4-10 microns).
Core Research Laboratories
Lifespan-Rhode Island Hospital
Fluorescence Activated Cell Sorter (FACS)

Contact: Paul Monfils

Becton Dickinson (BD) Biosciences FACS Vantage Flow CytometerHigh-speed cell sorter. Two lasers analyze cells on 8 parameters. Side/ forward light scatter. 6 different fluorescent color detection. Simultaneously sort up to four populations of cells. Sort 1+ cell type(s) into 6, 24, and 96 well tissue culture plates.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Fluorescence Activated Cell Sorter (FACS)

Contact: Paul Monfils

Becton Dickinson (BD) Biosciences FACSort Flow CytometerAnalytical flow cytometer. Two lasers analyze cells on 6 parameters. Side/ forward light scatter. 4 different fluorescent color detection.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Biosafety Cabinet

Contact: Paul Monfils

Laminar Flow Hood Filter capable of removing 99.97% of particles greater than 0.3 microns.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Knife Sharpener

Contact: Paul Monfils

Hecker Instruments, Inc. Knife SharpenerUsed to sharpen microtome/cryostat knife.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Microwave Oven

Contact: Paul Monfils

Sharp Microwave OvenTissue microwave fixation.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Oven

Contact: Paul Monfils

Fisher Scientific OvenUsed to melt paraffin from paraffin- embedded sections.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Paraffin Embedding Workstation

Contact: Paul Monfils

Miles Scientific Tissue-Tek IIIParaffin embedding sample station (tissue, bone, cell pellet, etc.).
Core Research Laboratories
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Tissue Processor

Contact: Paul Monfils

Miles Scientific Tissue-Tek-VIP Tissue ProcessorAutomated sample processing (tissue, bone, cell pellet, etc.) for paraffin embedding purposes.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Hybridization Oven

Contact: Carol Ayala

Panomics-Luminex Hybridization ovenHorizontal air flow oven for optimal temperature uniformity.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Imaging System - Camera

Contact: Ginny Hovnesian

Diagnostics SPOT 110-2 Digital Camera Digital Imaging of samples.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Imaging System - Camera

Contact: Ginny Hovnesian

Olympus SPOT IDEA 3.0 MP Digital Camera Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Imaging System - Camera

Contact: Ginny Hovnesian

SPOT RT3 Slider -43C F-MT Digital Camera Attached to Nikon TE-800. Digital Imaging of samples. Ideal for brightfield color imaging, fluorescence microscopy, FISH, GFP imaging, immuno- fluorescence, 3D convolution. CCD cooled to -43.3. 1.92 MP. 1-16x. 14-bit x 20MHz capture, 40MHz live mode, interline progressive scan, FireWire interface.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Imaging System - Dark Room

Contact: Paul Monfils

Dark Room Related equipment eg., automatic processors, dryers, et alSample photo development.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Imaging System - Photo Enlarger

Contact: Carol Ayala

Durst Laborator 1200 Photographic Enlarger Sample digital imaging using high performance enlarger.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

Contact: Carol Ayala

Bausch Lomb StereomicrosopesVisualization with incident light illumination.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

Contact: Ginny Hovnesian

NIKON E-800 Fluorescent /Brightfield MicroscopeFluorescence/Brightfield- micro- scope slides only. CFI60 optical system. 0.5x magnification with 50mm field of view. Can be coupled with 2x projection lens to permit macrophotography at 1:1 magnification. Tube lens focal length of 200mm. 10 types of condensers available.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

Contact: Ginny Hovnesian

Nikon TE 200 Inverted Fluorescent/Brightfield MicroscopeFluorescence/Brightfield Microscope- petri dish/microscope slides on cell/slice culture etc. Phase contrast and fluorescence.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

Contact: Paul Monfils

Olympus BHTU Upright Light MicroscopeLight Microscope for viewing tissue or cell samples on microscope slides. 45mm parfocal distance system, corrected for a mechanical tube length of 160mm. Two types of standard objectives, D Achromats and D Plan Achromats, magnifications of 4x, 10x, 20x, 40x, 100x. FN20. Equipped for epifluorescence microscopy.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

Contact: Paul Monfils

Olympus IMT-2 Inverted Light MicroscopeLight Microscope use to view cell/slice/tissue culture samples (microscope slide or petri dish). Inverted research microscope equipped with phase contrast optics.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

Contact: Carol Ayala

Zeiss S-16 Light MicroscopeLight Microscope used to view 1 micron sectioned resin-embedded samples.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope

NIKON C1Si Spectral Live Cell Confocal Inverted Microscope System For use with microscope slide. Four diode lasers that excite at 402, 488, 561, & 638 and has spectral capabilities. Suitable for tissue, live cell imaging, time events, FRAP, FRET, deconvolutions, colocalization analysis and 3D reconstructions.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microscope - Electron

Contact: Carol Ayala

Morgagni 268 Fully Digitized Transmission Electron Microscope (TEM)Ultrastructural analysis (tissue, cells) on stained ultra-thin sections contrasted with uranyl acetate and lead citrate. Examined with Morgagni 268 transmission electron microscope that is fully digitized, high performance, 100 kv, and images collected with an AMT Advantage 542 CCD camera system.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microtome

Contact: Carol Ayala

Bausch Lomb UltramicrotomeSectioning resin-embedded tissue; micron-nm thickness.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Microtome

Contact: Paul Monfils

Reichert-Jung MicrotomeParaffin embedded tissue sectioning (approximately 2-20 microns).
Core Research Laboratories
Lifespan-Rhode Island Hospital
Vibratome

Contact: Carol Ayala

Bausch Lomb VibratomesSectioning agarose-embedded tissue.
Core Research Laboratories
Lifespan-Rhode Island Hospital
Vibratome

Contact: Paul Monfils

Vibratome 3000 Sectioning SystemFresh tissue sectioning. Thickness: 3- 20 microns.
DNA Sequencing Facility
Brown University
DNA Sequencer

Illumina Sequencing System, GAIIxDNA, transcriptome and gene regulation analysis
DNA Sequencing Facility
Brown University
DNA Sequencer

Illumina Sequencing System, HiSeq2000DNA, transcriptome and gene regulation analysis
DNA Sequencing Facility
Brown University
DNA Sequencer

Illumina Sequencing System, HiSeq2500DNA, transcriptome and gene regulation analysis
Environmental Chemistry Facility
Brown University
Analyzer - Discrete Analyzer

Westco Smartchem 200 Used to determine Nitrate/Nitrite, Phosphate, Ammonia, Silicate, and other nutrient concentrations in water samples and soil extracts.
Environmental Chemistry Facility
Brown University
Analyzer - Elemental Analyzer

CE Elantech, Carbon-Nitrogen NC2100Analysis of carbon, nitrogen, and sulfur concentration of solid samples
Environmental Chemistry Facility
Brown University
Analyzer - Inorganic Carbon Analyzer

UIC, INC Inorganic Carbon AnalyzerMeasures total inorganic carbon by automated acidification and coulometric detection in a wide variety of sample matrices. Solid samples ranging from low ppm to 100% inorganic carbon can be analyzed with this system.
Environmental Chemistry Facility
Brown University
Analyzer - Mercury Analyzer

Milestone DMA-80 Direct Mercury Analyzer Determines mercury content of solid and liquid samples.
Environmental Chemistry Facility
Brown University
Analyzer - Water Isotope

Picarro L1102-I Measures delta deuterium/hydrogen (D/H) ratio and delta 18O/16O in liquid water
Environmental Chemistry Facility
Brown University
Freeze Dry System

Labconco FreeZone 6 Liter For removing water and other solvents from frozen samples by sublimation.
Environmental Chemistry Facility
Brown University
Liquid Chromatography System

Dionex DX500Ion chromatography analysis of ions in marine and freshwater samples
Environmental Chemistry Facility
Brown University
Microwave Digestion System

Milestone UltrawaveUsed to digest solid samples (soils, sediments, rocks, plants, tissues), for elemental analysis.
Environmental Chemistry Facility
Brown University
Spectrometer - Atomic Absorption Spectrometer-Graphite Furnace (GFAAS)

Perkin Elmer AAnalyst 600 Graphite Furnace This spectrometer is useful for measuring trace levels of metals in water and soil.
Environmental Chemistry Facility
Brown University
Spectrometer - Atomic Emission Spectrometer (AES)

Jobin Yvon JY2000 Ultrace Inductively coupled plasma atomic emission spectrometer (ICP-AES) Analysis of most elements with atomic weights above 10.
Environmental Chemistry Facility
Brown University
X-Ray Fluorescence - Handheld

Innov-X Systems Alpha 4000 Handheld Non-destructive elemental analysis on a variety sample types for concentrations of some metals ranging from about 20 ppm to 10%.
Environmental Chemistry Facility
Brown University
X-ray Fluorescence Spectrometer

Phillips PW1480 wavelength dispersive sequential diffractometer with a PW1510 autosamplerThis system is used mainly for elemental analysis of finely ground sediments, soils, or rocks (sample sizes >3 g), prepared as pressed powders.
Flow Cytometry and Sorting Facility
Brown University
Fluorescence Activated Cell Sorter (FACS)

Becton Dickinson (BD) Biosciences FACS Aria IICell counting, sorting, biomarker detection
Genomics & Sequencing Center
The University of Rhode Island
Bioanalyzer

Contact: Janet A. Atoyan, Genomics Technician

Agilent Bioanalyzer 2100Provides fast and automated separation, sizing and quantification of DNA, RNA and proteins by miniaturized Lab-on-a-Chip electrophoresis
Genomics & Sequencing Center
The University of Rhode Island
Bioinformatics Analysis - DNA Sequence and Protein Analysis

Contact: Janet A. Atoyan, Genomics Technician

Software: DNAStar Lasergene Core SuiteComprehensive suite of software modules for DNA, RNA, and protein sequence analysis
Genomics & Sequencing Center
The University of Rhode Island
Bioinformatics Analysis - Next Generation DNA Sequence Assembly

Contact: Janet A. Atoyan, Genomics Technician

Software: CLCbio Genomics Workbench Software for analyzing, comparing, and visualizing Next Generation Sequencing data
Genomics & Sequencing Center
The University of Rhode Island
Centrifuge

Contact: Janet A. Atoyan, Genomics Technician

Beckman Coulter Allegra 25R Refrigerated CentrifugeCentrifuge for pelleting cells, tissues and macromolecules
Genomics & Sequencing Center
The University of Rhode Island
Centrifuge

Contact: Janet A. Atoyan, Genomics Technician

Thermo Savant DNA110 SpeedVac Vacuum CentrifugeCentrifugal concentration system for drying low-volume ethanol or isopropanol precipitates of DNA and RNA
Genomics & Sequencing Center
The University of Rhode Island
Cryostat

Contact: Janet A. Atoyan, Genomics Technician

Vibratome 5000 Advanced CryostatPerforms histological sectioning of unfixed frozen cells and tissues.
Genomics & Sequencing Center
The University of Rhode Island
Disrupter

Contact: Janet A. Atoyan, Genomics Technician

Covaris S220 High Performance UltrasonicatorAutomated acoustic disruption and homogenization of cells and tissue samples using focused ultrasonic energy at 500 KHz. Performs DNA Shearing
Genomics & Sequencing Center
The University of Rhode Island
Disrupter

Contact: Janet A. Atoyan, Genomics Technician

QIAGEN TissueLyserProvides rapid and efficient disruption of cells and tissues
Genomics & Sequencing Center
The University of Rhode Island
DNA Sequencer

Contact: Janet A. Atoyan, Genomics Technician

Applied Biosystems 3130xl & 3500xl Genetic AnalyzersDNA Sanger Sequencing & Fragment Analysis: Fluorescence-based instruments utilizing capillary electrophoresis for DNA sequencing and fragment analysis
Genomics & Sequencing Center
The University of Rhode Island
DNA Sequencer

Contact: Janet A. Atoyan, Genomics Technician

Illumina MiSeq DNA NextGen SequencingPerforms clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting
Genomics & Sequencing Center
The University of Rhode Island
Electrophoresis System

Contact: Janet A. Atoyan, Genomics Technician

Sage Science BluePippin DNA Electrophoresis SystemA preparative electrophoresis platform that separates and extracts DNA fragments using pre-cast gel cassettes
Genomics & Sequencing Center
The University of Rhode Island
Fluorometer

Contact: Janet A. Atoyan, Genomics Technician

Invitrogen QubitFluorometer that uses fluorescent dyes bound to specific molecules to quantify DNA, RNA and proteins
Genomics & Sequencing Center
The University of Rhode Island
Imaging System - Camera

Contact: Janet A. Atoyan, Genomics Technician

Zeiss AxioCam HRc high-resolution imaging systemsA digital Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module. For use on the AxioImager upright light microscope
Genomics & Sequencing Center
The University of Rhode Island
Library Preparation System

Contact: Janet A. Atoyan, Genomics Technician

IntegenX Apollo 324 System NextGen Sequencing (NGS) Library Preparation SystemAutomated liquid handling instrument dedicated to the preparation of sample libraries for Next Generation Sequencing
Genomics & Sequencing Center
The University of Rhode Island
Microarray Platform

Contact: Janet A. Atoyan, Genomics Technician

BioLog OmniLog Phenotype Microarray System Plate Incubator/ReaderUses Phenotype Microarrays in microtiter plates to test for unique phenotypes or cell functions
Genomics & Sequencing Center
The University of Rhode Island
Microscope

Contact: Janet A. Atoyan, Genomics Technician

Zeiss AxioImager M2 Upright Light MicroscopeFor use with the AxioImager upright light microscope equipped for digital image acquisition with a Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module
Genomics & Sequencing Center
The University of Rhode Island
PCR Thermal Cycler

Contact: Janet A. Atoyan, Genomics Technician

Agilent Mx3005P and Roche LC480 qPCR Systems3 Quantitative PCR (qPCR) instruments. Used for highly accurate qualitative and quantitative detection of nucleic acids and gene expression .
Genomics & Sequencing Center
The University of Rhode Island
PCR Thermal Cycler

Contact: Janet A. Atoyan, Genomics Technician

Eppendorf Mastercycler ep Gradient S and MJ Research PTC-100(3) Thermal cyclers in 96-well format; peltier elements control the temperature of the block for PCR chemistry
Genomics & Sequencing Center
The University of Rhode Island
PCR Workstation

Contact: Janet A. Atoyan, Genomics Technician

AirClean Systems 600 PCR WorkstationCombination workstation provides an ISO 5 (FS209E) Class 100 clean air environment and UV light sterilization
Genomics & Sequencing Center
The University of Rhode Island
Robotic Workstation - Automated Pipetting

Contact: Janet A. Atoyan, Genomics Technician

Eppendorf epMotion 5075 VAC Pipetting WorkstationAutomated pipetting workstation enables fast and reproducible liquid handling for a variety of applications
Genomics & Sequencing Center
The University of Rhode Island
Robotic Workstation - Sample Preparation

Contact: Janet A. Atoyan, Genomics Technician

QIAGEN QIAcube Spin Column RobotAutomated protocols for purification of plasmid DNA, genomic DNA, RNA, viral nucleic acids, and proteins
Genomics & Sequencing Center
The University of Rhode Island
Spectrophotometer

Contact: Janet A. Atoyan, Genomics Technician

Thermo Scientific NanoDrop 8000Spectrophotometer that accurately measures up to eight individual 1-2 microliter samples simultaneously
Genomics Facility
Brown University
Bioanalyzer

Agilent Bioanalyzer 2100Microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cells
Genomics Facility
Brown University
Capillary Electrophoresis

Advanced Analytical, Fragment AnalyzerAnalyze DNA fragments for Next-Gen Sequencing, genotyping, checking RNA quality and quantity, and working with microsatellite simple sequence repeats (SSRs).
Genomics Facility
Brown University
Cell Counter

Life Technologies Automated Countess Cell CounterMeasure cell count and viability (live, dead, and total cells) using the standard trypan blue technique.
Genomics Facility
Brown University
Centrifuge

Sorvall Legend T BenchtopLow to medium speed centrifugation
Genomics Facility
Brown University
Centrifuge - Ultra

Beckman Coulter Optima Max High speed centrifugation with MLA130, TLA110 & TLA100 Rotors
Genomics Facility
Brown University
Disrupter

Covaris S220 High Performance UltrasonicatorDNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization
Genomics Facility
Brown University
Fluorescence Activated Cell Sorter (FACS)

Becton Dickinson (BD) Biosciences FACS Calibur Flow cytometry cell analysis and cell sorting
Genomics Facility
Brown University
Hybridization Oven

Agilent G2534A Microarray hybridization oven
Genomics Facility
Brown University
Imaging System

LiCor Odyssey Clx InfraredWestern blot analysis, EMSA, protein arrays, In-Cell Western Assays, On-Cell Westerns, in vivo imaging, Coomassie gel documentation, DNA gel documentation, and tissue section analysis.
Genomics Facility
Brown University
Imaging System

Molecular Dynamics Typhoon 9410 Imaging system for gel sandwiches agarose and polyacrylamide gels membranes, microplates and microarrays.
Genomics Facility
Brown University
Microarray Platform

Affymetrix Gene Chip Instrument SystemA fully integrated platform for Affymetrix microarrays
Genomics Facility
Brown University
Microarray Scanner

Molecular Devices GenePix Scanner 4000BTwo color microarray scanner
Genomics Facility
Brown University
Microplate Reader

Molecular Devices Spectra Max M5 Detects UV-Visible Absorbance (Abs), Fluorescence Intensity (FI), Time-Resolved Fluorescence (TRF), Fluorescence Polarization (FP), Glow Luminescence (Lumi)
Genomics Facility
Brown University
PCR Thermal Cycler

Applied Biosystems 7900 Fast Real Time PCR System 96- and 384-well fast real time, quantitative PCR formats with fully automated robotic loading
Genomics Facility
Brown University
PCR Thermal Cycler

Applied Biosystems viia-7-real-time-systemMedium to high throughput 96- and 384-well fast real time quantitative PCR formats with fully automated robotic loading, medium to high throughput
Genomics Facility
Brown University
PCR Thermal Cycler

Eppendorf Gradient Mastercycler Gradient cycler enables the temperature across the entire block to be varied within a range of up to 20 C; it can be programmed with every temperature step. For use by genomics facility personnel.
Genomics Facility
Brown University
Spectrophotometer

Thermo Scientific NanoDrop 1000 A microvolume spectrophotometer for measuring DNA, RNA, and protein.
Genomics Facility
Brown University
Technical Assistance - Affymetrix Microarray

ServiceService to provide Affymetrix gene expression array service
Genomics Facility
Brown University
Technical Assistance - Genomics and DNA Sequencing Training

ServiceService to provide Genomics and DNA Sequencing Training
Genomics Facility
Brown University
Technical Assistance - Next Generation (NextGen) Sequencing (NGS)

ServiceService to provide Illumina platform based NextGen sequencing
Leduc Bioimaging Facility
Brown University
Bioinformatics Analysis - Molecular Devices, MetaMorph

Software: Molecular Devices, MetaMorph Software for microscopy automation & image analysis
Leduc Bioimaging Facility
Brown University
Critical Point Dryer

Ladd Research IndustriesRemoves liquid from biological specimens for SEM
Leduc Bioimaging Facility
Brown University
Glow Discharge Unit

Emitech K100XAdds a charge to make TEM samples hydrophilic
Leduc Bioimaging Facility
Brown University
Microscope

Leica TCS SP2 ConfocalOptical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility
Brown University
Microscope

Olympus MultiPhoton Laser Scanning Deep optical sectioning of fluorescently labeled samples with SIM photoactivation
Leduc Bioimaging Facility
Brown University
Microscope

Zeiss Axiovert 200M FluorescenceImaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility
Brown University
Microscope

Zeiss Axiovert 200M FluorescenceImaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility
Brown University
Microscope

Zeiss LSM 410 ConfocalOptical sectioning of samples labeled with fluorescent indicators with Microcosm UV laser upgrade
Leduc Bioimaging Facility
Brown University
Microscope

Zeiss LSM 510 Meta ConfocalOptical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility
Brown University
Microscope

Zeiss LSM 710 ConfocalOptical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility
Brown University
Microscope

Zeiss Lumar Stereo FluorescenceImaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility
Brown University
Microscope - Electron

Hitachi S-2700 Scanning Electron Microscope (SEM) Transmission electron microscopy with PCI Digital Imaging Accessory
Leduc Bioimaging Facility
Brown University
Microscope - Electron

Philips 410 Transmission Electron Microscope (TEM) Scanning electron microscopy with AMT Camera Accessory
Leduc Bioimaging Facility
Brown University
Microtome

Reichert UltramicrotomeUltrathin sectioning for TEM
Leduc Bioimaging Facility
Brown University
Microtome Diamond Knife Set

Diatome DKSUsed on Reichert microtome to cut ultrathin sections for TEM
Leduc Bioimaging Facility
Brown University
Sputter Coater System

Emitech K550Covers an EM specimen with a thin layer of conducting material
Leduc Bioimaging Facility
Brown University
Technical Assistance - Bioimaging

ServiceService to provide Bioimaging Technical Assistance
Leduc Bioimaging Facility
Brown University
Technical Assistance - Bioimaging Training

Service Service to provide Bioimaging Training
Magnetic Resonance Imaging Facility
Brown University
Magnetic Resonance Imaging (MRI) Scanner

Siemens 3 Tesla TIM Trio.Brain structure and function in normal and clinical populations as well as studies of other body systems, non-invasive animal imaging and materials science.
Marine Science Research Facility
The University of Rhode Island
Analyzer - Dissolved Gas

Contact: Malcolm McFarland

Bay Instruments Membrane Inlet Mass Spectrometer- Dissolved Gas AnalyzerMass Spectrometer: Quantifies dissolved gases
Marine Science Research Facility
The University of Rhode Island
Analyzer - Multiparameter Water Analyzer

Contact: Malcolm McFarland

YSI Professional Plus Hand Held Multiparameter Water Meter Measures temperature, salinity, dissolved oxygen (DO), and pH
Marine Science Research Facility
The University of Rhode Island
Analyzer - Nutrient

Contact: Malcolm McFarland

Lachat QuickChem 8500 Flow Injection Nutrient Auto AnalyzerMeasures dissolved nutrients in water, Ammonia, Phosphate, Nitrite, Nitrate, and Silicate
Marine Science Research Facility
The University of Rhode Island
Aquatic Culture - Algae and Live Feed Room

Contact: Danielle Duquette

Various manufacturersK-walls, small rearing tanks for live feed, flowing seawater and freshwater
Marine Science Research Facility
The University of Rhode Island
Aquatic Culture - Phytoplankton Culture Wheels

Contact: Danielle Duquette

Various manufacturersMotorized and water driven, clear plexiglass, ambient and experimental temperature control, can accommodate culture bottles of differing sizes (1-3L)
Marine Science Research Facility
The University of Rhode Island
Dechlorination System - Freshwater

Contact: Danielle Duquette

Various manufacturers2 Freshwater dechlorination tanks
Marine Science Research Facility
The University of Rhode Island
Disrupter

Contact: Malcolm McFarland

Biospec Mini Bead BeaterShakes tubes with beads to disrupt cells, DNA , RNA
Marine Science Research Facility
The University of Rhode Island
Disrupter

Contact: Malcolm McFarland

Branson Digital Ultasonic Liquid SonifierDisrupts cells
Marine Science Research Facility
The University of Rhode Island
Environmental Chamber

Contact: Danielle Duquette

EnvironAir Environmental Chamber100 sq ft Temperature control, Two range 4-24 C, Two range -4-24 C (to simulate polar conditions), On generator back up and emergency monitoring systems. (4 Units)
Marine Science Research Facility
The University of Rhode Island
Flowing Seawater System

Contact: Danielle Duquette

Various manufacturersRaw-Ambient temperature and Filtered- Chilled, Heated, Ambient. UV treated, air supply, emergency monitoring systems
Marine Science Research Facility
The University of Rhode Island
Fluorescence Activated Cell Sorter (FACS)

Contact: Andrea Drzewianowski

Becton Dickinson (BD) Biosciences Influx Flow Cytometer and Cell SorterMeasures light scatter and fluorescence of cells. Sorts cells based on measured properties.
Marine Science Research Facility
The University of Rhode Island
Fluorometer

Contact: Malcolm McFarland

Satlantic Fluorescence Induction Relaxation Fluorometer (FIRE)Measures variable fluorescence in phytoplankton
Marine Science Research Facility
The University of Rhode Island
Fluorometer

Contact: Malcolm McFarland

Turner Designs 10-AU (Chlorophyll) Field Fluorometer A rugged, field-portable instrument that can be set up for continuous-flow monitoring or discrete sample analyses. Measures fluorescence of samples. Set up for chlorophyll fluorescence both extracted and in vivo
Marine Science Research Facility
The University of Rhode Island
Fluorometer

Contact: Malcolm McFarland

Life Technologies Qubit FluorometerQuantifies DNA, RNA, and protein
Marine Science Research Facility
The University of Rhode Island
Freezer - Walk-in

Contact: Danielle Duquette

-20 C Walk-In Freezer185 sq ft Long term storage, On generator back up and emergency monitoring systems
Marine Science Research Facility
The University of Rhode Island
Homogenizer

Contact: Malcolm McFarland

Polytron Homogenizer PT-10-35-GT Rapidly breaks down plant and animal tissue for chemical analysis, prepares emulsions and samples for titrations, and extracts pesticides in soil samples. Provides fast, reproducible homogenization, emulsion, dispersion, and mixing, with consistent sample-to-sample uniformity.
Marine Science Research Facility
The University of Rhode Island
Imaging System - Camera

Contact: Malcolm McFarland

Allied Digital Stingray Firewire Microscope Camera Video and still images C-mount
Marine Science Research Facility
The University of Rhode Island
Imaging System - Fluid Particle Imaging

Contact: Malcolm McFarland

Fluid Imaging Technologies FlowCam Imaging Particle Analysis: Images particles suspended in solution.
Marine Science Research Facility
The University of Rhode Island
Incubator

Contact: Malcolm McFarland

Percival Incubator/Growth ChamberTemperature and light controlled incubator for environmental applications
Marine Science Research Facility
The University of Rhode Island
Microplate Reader

Contact: Malcolm McFarland

Molecular Devices Spectramax M5 Measures Fluorescence Intensity, Absorbance, Time Resolved Fluorescence, Fluorescence Polarization and Luminescence in cuvettes and multiple sized microplates.
Marine Science Research Facility
The University of Rhode Island
Microscope

Contact: Malcolm McFarland

Nikon inverted MicroscopeMicroscopy: Works with Stingray Camera
Marine Science Research Facility
The University of Rhode Island
Microscope

Contact: Malcolm McFarland

Olympus SZX16 Stereo MicroscopeMicroscopy. Works with Stingray Camera
Marine Science Research Facility
The University of Rhode Island
PCR Thermal Cycler

Contact: Malcolm McFarland

Eppendorf Master Cycler Pro Replicates DNA
Marine Science Research Facility
The University of Rhode Island
PCR Thermal Cycler

Contact: Malcolm McFarland

Stratagene QPCR Mx3000PInstrument for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Quantitative PCR Filters- FAM/Syber Green, Rox, Hex, CY3, CY5
Marine Science Research Facility
The University of Rhode Island
Photoperiod controller

Contact: Danielle Duquette

Various manufacturersWattstopper controller(Blount), Various individual timers
Marine Science Research Facility
The University of Rhode Island
Pier Access

Contact: Danielle Duquette

Access to Graduate School of Oceanography pierAccess to pier for deployment, collection, testing. Water depths 18-15 feet to intertidal zone
Marine Science Research Facility
The University of Rhode Island
Radiometer

Contact: Malcolm McFarland

Biospherical Instruments Quantum Scalar Laboratory (QSL) Radiometer - PAR Light Meter Measures Photosynthetically Active Radiation (PAR)
Marine Science Research Facility
The University of Rhode Island
Shaker

Contact: Malcolm McFarland

Thermo Max-Q Orbital Shaker Table Orbital shaker with 18x24 in platform and variety of clamps
Marine Science Research Facility
The University of Rhode Island
Shaker

Contact: Malcolm McFarland

Thermo Max Q Incubated ShakerHeated incubated shaker
Marine Science Research Facility
The University of Rhode Island
Spectrometer

Contact: Malcolm McFarland

Ocean Optics Jaz SpectrometerOptical sensing instrumentation that measures light wavelengths. Its unique features and expandable platform makes it uniquely suited for field applications, remote sensing, process flow and quality assurance.
Marine Science Research Facility
The University of Rhode Island
Spectrophotometer

Contact: Malcolm McFarland

Thermo Scientific NanoDrop 1000Microvolume UV-Vis spectrophotometer that quantifies DNA, RNA, and protein from small 1-2 microliter sample size
Marine Science Research Facility
The University of Rhode Island
Tank - Laminar Flow

Contact: Danielle Duquette

Laminar Flow Tank1000 gal, Seawater or Freshwater, Multiple speeds with precision control. Experimental chamber visable from 5 sides
Marine Science Research Facility
The University of Rhode Island
Tank - Mesocosm

Contact: Danielle Duquette

Various manufacturers10, 5 ft deep outdoor mesocosms, with available raw ambient seawater flow
Marine Science Research Facility
The University of Rhode Island
Vacuum Manifold

Contact: Malcolm McFarland

Vacuum Filter Manifold Allows for filtration of 5 ports simultaneously, 25 and 47 mm filter cups available
Marine Science Research Facility
The University of Rhode Island
Worksation - Marine General Wet Lab

Contact: Danielle Duquette

Various manufacturers3 Buildings, 7,000 sq ft indoor, and nearly unlimited outdoor space, Multiple insulated tank sizes, various sized aquaria, possible to perform simultaneous replicates
Marine Science Research Facility
The University of Rhode Island
Workstation - Marine Pathology and Transgenics Laboratory and Systems

Contact: Danielle Duquette

Various manufacturersOzone treated effluent and separate effluent drain
Mass Spectrometer Analytical Facility
Brown University
Mass Spectrometer

Contact: Alberto Saal

Thermo Scientific Multi-collector inductively coupled plasma mass spectrometer, ICP-MS, Neptune PlusThis is a multi-collector ICP-MS equipped with nine Faraday cups and eight ion counters, which allows us to monitor multiple masses simultaneously providing precise isotope ratio measurement.
Mass Spectrometer Analytical Facility
Brown University
Mass Spectrometer

Contact: Alberto Saal

Thermo Scientific Quadrupole inductively coupled plasma mass spectrometer, ICP-MS, X-series-2This is a single collector ICP-MS that allows us to measure precise elemental composition at sub-ppb level concentration.
Mass Spectrometer Analytical Facility
Brown University
Laser Ablation

Contact: Alberto Saal

Photon-machines Analyte G2, 193 nm excimer laser ablationThis 193 nm wave-length excimer laser allows us to perform in-situ analysis on a solid sample with a beam diameter as small as 3 µm. To determine the elemental abundances the laser is coupled with the single collector inductively coupled plasma mass spectrometer ICPMS and to determine the isotope ratios the laser is coupled with multi collector ICPMS.
Mass Spectrometer Analytical Facility
Brown University
Clean lab, Trace metal free

Contact: Alberto Saal

Pico Trace This Clean Lab is equipped with Millipore water filtration system that provides greater than 18MΩ Milli-Q water. The working stations in this Clean Lab meet ISO class 4 standard (equivalent to FS class 10) allowing us to perform ultra-low blank chemical analysis.
Mass Spectrometry Facility
Brown University
Gas Chromatograph - Mass Spectrometer (GC - MS)

Hewlett-Packard (Agilent) GCD 1800C This system is suitable for separation of complex mixtures by gas chromatography (GC) and identification by mass spectrometry.  It is limited to low molecular weight and volatile molecules (mass limit 450 Da).
Mass Spectrometry Facility
Brown University
Liquid Chromatography - Mass Spectrometer (LC - MS)

Agilent 6230 Mass TOF This instrument can detect and identify compounds in amounts smaller than two trillionths of a gram (2 picograms), making the Agilent 6230 a powerful tool for food safety, toxicology and other measurements where minute amounts of compounds must be identified.
Mass Spectrometry Facility
Brown University
Mass Spectrometer

Applied Biosystems Voyager DE PRO MALDI-TOFThe Voyager DE PRO is a time-of-flight (TOF) mass spectrometer equipped with a matrix-assisted laser desorption ionization (MALDI) ion source.  This instrument is routinely used for analysis of organic molecules, natural products, and macromolecules, including recombinant proteins, oligonucleotides, polysaccharides and synthetic polymers.
Mass Spectrometry Facility
Brown University
Mass Spectrometer

JEOL JMS-600H double focusing magnetic sector The JMS-600H is a compact double-focusing, high-resolution, magnetic sector mass spectrometer.  This instrument is equipped with electron impact ionization (EI), Chemical Ionization (CI), and fast atom bombardment ionization (FAB) for characterization of synthetic organic, inorganic, and biological molecules. This instrument is also used for routine exact mass measurement of organic molecules. 
Mass Spectrometry Facility
Brown University
Mass Spectrometer

Thermo LXQ linear ion trap with Surveyor HPLC systemThe LXQ has capabilities similar to the conventional 3D ion trap such as LCQ Deca. It is based on linear ion trap technology that has faster cycle time.  It is capable of data-dependent LC/MSn analysis. 
Mass Spectrometry Facility
Brown University
Mass Spectrometer

Thermo LCQ Deca XP Max ion trap with Shimadzu HPLC systemThe LCQ Deca XP Max is equipped with electrospray (ESI) and APCI ionization sources. It is capable of mass analysis of a broad range of molecules that are relatively polar, nonvolatile and thermally labile.  This instrument is used for routine molecular weight determination of compounds from organic, inorganic, natural products, small proteins and peptides, and oligonucleotides. 
Media Prep Kitchen
Brown University
Media Prep Kitchen for Drosophila

ServiceService to provide bottles and vials of Drosophila media
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Fluorescence Activated Cell Sorter (FACS)

Becton Dickinson (BD) Biosciences FACSCantoAnalytical Flow Cytometer: 2 lasers, 6 colors
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Gel Imager

Bio-Rad Chemidoc XRS The ChemiDoc XRS+ system is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab software to optimize imager performance for fast, integrated, and automated image capture and analysis of various samples.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Gel Imager

Bio-Rad Molecular Imager FX systemImager with 50 micron resolution and a 5 order of magnitude linear dynamic range for fluorescence and radioisotopic imaging. You can also image and accurately quantitate chemiluminescent samples.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Magnetic cell sorter

Miltenyi AutoMACSAutomated cell sorter, for separating cell suspensions labeled with magnetic beads
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microplate Reader

Molecular Devices Spectramax Gemini EM Fluorescence Microplate ReaderEnables top and bottom reading of microplates over a greater range of fluorescence intensities—all without the use of filters.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microplate Reader

Perkin Elmer TopCount NXT Microplate Scintillation and Luminescence CounterTopCount NXT analyzes two, six, or twelve samples at a time, and counts samples in 24-, 96-, and 384-well microplates, as well as microcentrifuge tubes. It can count gammas, betas, or luminescent samples.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microscope

Leica MZ FLIII Stereo Fluorescent dissection microscope Dissection microscope with Leica color camera DC300F.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microscope

Nikon 80i Upright Fluorescence MicroscopeUpright microscope with color CCD camera Spot Insight 2
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microscope

Nikon TE2000E Inverted fluorescence, A live cell imaging microscope, with cooled CCD camera Roper CoolSnap HQ
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microscope

Zeiss AxioImager M2 Upright Microscope,Upright microscope with color CCD camera AxioCam MRC.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Microscope

Nikon TE2000E Inverted fluorescence,A Multicolor fluorescence widefield microscope, with stage incubator, specialized in live cell imaging
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
PCR Thermal Cycler

Applied Biosystems ABI 750096-well quantitative PCR
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Spectrophotometer

Bio-Rad smartspec 90-260 V, UV/visible benchtop spectrophotometer for nucleic acid and protein quantitation, wavelength range 200–800 nm, built-in thermal printer
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Spectrophotometer

Thermo Scientific NanoDrop 2000 A full spectral microvolume UV-Vis analysis spectrophotometer for measuring DNA, RNA, and protein.
Molecular Biology and Imaging Core
Care New England-Women and Infants Hospital
Suspension Array System

Bio-Rad BioPlex 200 Detection and quantification of multiple analytes (proteins and peptides, or nucleic acids) in a single sample volume. 
Molecular Characterization Facility
The University of Rhode Island
Nuclear Magnetic Resonance (NMR) Spectrometer

Contact: Prof. David Rowley

Agilent NMRS 500 with OneNMR ProbeNMR Spectroscopy
Molecular Pathology
Lifespan-Rhode Island Hospital
Bioanalyzer

Agilent Bioanalyzer MX3005P Two assay principles: electrophoresis and flow cytometry. Minimal sample consumption: 1-4 microliters. Digital data. Contamination-free switch of methods.
Molecular Pathology
Lifespan-Rhode Island Hospital
Biological Safety Cabinet

HEPA filter and NuAire laminar flow hood Filter capable of removing 99.97% of particles greater than 0.3 micronss.
Molecular Pathology
Lifespan-Rhode Island Hospital
Biospecimen Banking - Freezer

ThermoForma Freezer - 80 C #8606Sample storage
Molecular Pathology
Lifespan-Rhode Island Hospital
Biospecimen Banking - Freezer

ThermoForma Freezer -20 C #3801Sample storage
Molecular Pathology
Lifespan-Rhode Island Hospital
Biospecimen Banking - Freezer

ThermoForma Refrigerator #3771Sample storage
Molecular Pathology
Lifespan-Rhode Island Hospital
Biospecimen Banking - Refrigerator

ThermoForma Ultra 932 Lo Freezer -80 C (2) Sample storage
Molecular Pathology
Lifespan-Rhode Island Hospital
Centrifuge

Eppendorf 5424 MicrocentrifugeAerosol-tight rotor. Max rcf: 20,238 x g. Automatic lid opening following application sequence. Low access height: 23 cm. Short spin, rpm/rcf setting as required
Molecular Pathology
Lifespan-Rhode Island Hospital
Centrifuge

ThermoForma refrigerated MicrocentrifugeWorking temperatures from -5 C to +40 C.
Molecular Pathology
Lifespan-Rhode Island Hospital
Cryostat

Leica Cryostat CM1850Frozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.
Molecular Pathology
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Balance

Mettler (PB303-S) semimicro balanceMass range of 0.01 mg- 120 g.
Molecular Pathology
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Histobath

Fisher Histobath 134Prevents development of microscopic ice crystals and sample distortion.
Molecular Pathology
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Microwave Oven

Amana (RFS18MPS) Microwave OvenTissue microwave fixation.
Molecular Pathology
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Microwave Oven

GE Microwave oven (JE1460BF001)Tissue microwave fixation.
Molecular Pathology
Lifespan-Rhode Island Hospital
Imaging System - Camera

Polaroid camera Instant recording of gels.
Molecular Pathology
Lifespan-Rhode Island Hospital
Imaging System - Slide Scanner

Aperio ScanScope Slide Scanner CS2Generates full color, high resolution digital images (cells, tissues and tissue arrays). 5 slide capacity. Image analysis software available. Stored and catalogued in searchable image data base.
Molecular Pathology
Lifespan-Rhode Island Hospital
Incubator

Fisher Scientific Dry Bath IncubatorPrecise temperature control for temperatures up to 130 C. Built in temperature sensing probe for improved temperature accuracy and control.
Molecular Pathology
Lifespan-Rhode Island Hospital
Laser Capture Microdissection System

Arcturus Autopix LCM-1110Automated laser capture microdissection of cells for RNA,DNA and proteins. Can isolate thousands of cells from FFPE tissues in minutes. 100-240V, 50-60Hz.
Molecular Pathology
Lifespan-Rhode Island Hospital
Laser Capture Microdissection System

Arcturus XT Laser Capture Microdissection System Automated IR and UV laser capture. Microdissection and cutting of cells for RNA, DNA and protein isolation. One modular platform with laser capture and cutting. Optional live-cell modules and camera. Any slide type. Wide range of objectives available, 2x-100x dry and 100x oil immersion.
Molecular Pathology
Lifespan-Rhode Island Hospital
Microscope

Olympus Fluorescent Microscope BX41Image Pro Imaging Software. Excitation available 330-385nm, 460-490nm, 510-550nm. Magnifications of 20,40, 100, 200 power. Both reflected light and sample fluorescence may be viewed through and recorded at the microscope.
Molecular Pathology
Lifespan-Rhode Island Hospital
Microscope

Olympus BX41 General Use MicroscopeOptical system: UIS2. Built in transmitted Koehler illuminator, 6V/30W bulb. Stage height movement by roller guide, stroke per rotation: 36.8mm. Full stroke range: 25mm. FN20, tube inclination 30 degrees. Stage size: 188 x 134 mm.
Molecular Pathology
Lifespan-Rhode Island Hospital
Microtome

Finesse 325 Microtome Used to prepare samples for observation under transmitted light or electron radiation. Microtome material varies depending on the specimen being sliced and the desired thickness of the sections cut.
Molecular Pathology
Lifespan-Rhode Island Hospital
PCR Thermal Cycler

Stratagene Multiplex PCR System MX4000Multiplex assays with up to 4 dyes. Single scanning fiber optic head. Four optic channels with user selected filters, use of a single PMT. Can use up to 5 targets in the same tube. 25 microliter sample size.
Molecular Pathology
Lifespan-Rhode Island Hospital
pH Meter

Accumet pH meter pH meter.
Molecular Pathology
Lifespan-Rhode Island Hospital
Robotic Workstation - Barcoding

Ventana Discovery System Automated staining module using bar code technology. Total automation in IHC staining of frozen/ paraffin embedded tissue, FISH and ISH using DNA, RNA or oligonucleotide probes on tissue or microarrays (gene expression).
Molecular Pathology
Lifespan-Rhode Island Hospital
Spectrophotometer

Eppendorf BioPhotometer 50 microliter volumes. Automatic calculation of dilution factors. Measures wave lengths: 230, 260, 280, 340, 405, 490, 550, 595, 650 nm. Spectral bandwidth: 5nm at 230-340nm, 7nm at 405-650nm. Photometric random error +/- 0.002A at 0A, +/- 0.005A at 1A.
Molecular Pathology
Lifespan-Rhode Island Hospital
Suspension Array System

Beecher Manual Tissue Microarrayer Generates multiple specimen slides that can contain hundreds of individual tissues. Up to 100 tissue cores per paraffin block. Use for same histochemical and molecular detection techniques as with regular sections.
Molecular Pathology
Lifespan-Rhode Island Hospital
Vacuum Oven

Napco Model 5831 vacuum ovenCapacity: 0.45 cu ft. Temp range: 35 C to 200 C. 30-in Hg vacuum capability. Vacuum bleed valves permit pulling of vacuums as high as 30 inches H. Full view observation window with latched door and built in safety to prevent thermal runaway.
Molecular Pathology
Lifespan-Rhode Island Hospital
Waterbath

PolyScience refrigerated/heated (9106) circulating waterbathWorking temperatures from -40 C to +200 C. Temperature stabilities to ±0.005 C.
Mouse Transgenic and Gene Targeting Facility
Brown University
Biological Safety Cabinet

NuAire Safety Cabinets Class 2 Type A/B3Transgenics and gene targeting safety cabinets (2 units)
Mouse Transgenic and Gene Targeting Facility
Brown University
Centrifuge

Thermo IEC Centra CL3R Refrigerated CentrifugeTransgenics and gene targeting refrigerated centrifuge
Mouse Transgenic and Gene Targeting Facility
Brown University
Electroporation System

Bio-Rad Gene Pulsar IITransgenics and gene targeting electroporation system
Mouse Transgenic and Gene Targeting Facility
Brown University
Freezer

Custom BioGenic Systems Liquid Nitrogen (LN2) FreezerTransgenics and gene targeting liquid nitrogen freezer
Mouse Transgenic and Gene Targeting Facility
Brown University
Freezer

Thermo Fisher Scientific -80 CTransgenics and gene targeting -80 C freezer
Mouse Transgenic and Gene Targeting Facility
Brown University
Freezer

Frigidaire -20 C FreezerTransgenics and gene targeting freezer
Mouse Transgenic and Gene Targeting Facility
Brown University
Gene Targeting

ServiceGene targeting services through transfection and microinjection of murine embryonic stem (ES) cells to produce germline knockout (KO) or knockin (KI) mice
Mouse Transgenic and Gene Targeting Facility
Brown University
Incubator

NuAire CO2 water jacketed Incubators Transgenics and gene targeting incubators (3 units)
Mouse Transgenic and Gene Targeting Facility
Brown University
Microinjector

Eppendorf FemtoJet Microinjection SystemTransgenics and gene targeting pronuclear injection system
Mouse Transgenic and Gene Targeting Facility
Brown University
Micromanipulator

Eppendorf Transferman NK 2 MicromanipulatorsTransgenics and gene targeting micromanipulators (2 units)
Mouse Transgenic and Gene Targeting Facility
Brown University
Microscope

Nikon Eclipse TE200 Inverted MicroscopeTransgenics and gene targeting microinjection microscope
Mouse Transgenic and Gene Targeting Facility
Brown University
Microscope

Nikon Eclipse TS100 (cell culture scope)Transgenics and gene targeting cell culture scope
Mouse Transgenic and Gene Targeting Facility
Brown University
Microscope

Nikon SMZ1500 Zoom StereomicroscopesTransgenics and gene targeting dissecting microscopes (2 units)
Mouse Transgenic and Gene Targeting Facility
Brown University
Microscope

Nikon SMZ800 Zoom StereomicroscopesTransgenics and gene targeting surgical microscope
Mouse Transgenic and Gene Targeting Facility
Brown University
Technical Assistance - Karyotyping

ServiceService to determine euploidy of murine embryonic stem (ES) cells prior to microinjection
Mouse Transgenic and Gene Targeting Facility
Brown University
Technical Assistance -Transgenics and Gene Targeting

ServiceService to provide custom services related to microinjection, ES cell culture, mouse surgery, or mouse reproduction. The core facility will provide services and/or training related to our capabilities that are not specifically covered by our service list. These services are available for an hourly fee. Examples include: production of MEFs (murine embryonic fibroblasts), polar body biopsy, reproductive surgery, blastomere injection, frozen embryo shipment, training
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Cryopreserved Mouse Embryo Recovery

ServiceService to thaw and implant previously cryopreserved mouse embryos
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Cryopreserved Mouse Embryo Storage

ServiceService to store cryopreserved mouse embryos in liquid nitrogen (LN2)
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Derivation of Mouse Embryonic Stem (ES) cell lines

ServiceService to produce embryonic stem (ES) cells from an existing mouse line key words: murine embryonic stem cells
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Embryonic Stem (ES) Cell Injection

ServiceService to produce chimeric mice for analysis through microinjection of murine embryonic stem (ES) cells into blastocyst stage embryos.
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Mouse Colony Expansion

ServiceService to use superovulation and surgical implantation to produce large cohorts of age matched mice for experimentation or to quickly expand a mouse colony
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Mouse Embryo Cryopreservation

ServiceService to cryopreserve valuable mouse lines for storage or shipment to other investigators.
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Mouse In vitro Fertilization (IVF)

ServiceService to perform in vitro fertilization of mouse embryos
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Rederivation of Mouse Lines

ServiceService to rederive mouse lines obtained from a source other than a Brown University approved vendor. Rederived mouse lines may be housed in any campus mouse facility.
Mouse Transgenic and Gene Targeting Facility
Brown University
Transgenics and Gene Targeting - Transgenics

ServiceService to perform pronuclear microinjection of 0.5 dpc mouse embryos to produce transgenic founders on an FVB/N or C57/BL6 background. Custom backgrounds also available.
Mouse Transgenic and Gene Targeting Facility
Brown University
Water Purification System

Milli Q Biocel Transgenics and gene targeting water purification
Mouse Transgenic and Gene Targeting Facility
Brown University
Waterbath

Thermo Scientific Precision 260 Circulating Waterbath Transgenics and gene targeting circulating waterbath
Multiplex Facility
Lifespan-Rhode Island Hospital
Behavioral Phenotyping - Four Lane Rotarod

Emitter-Columbus Rotamex 5 ControllerUsed to assess motor coordination and balance
Multiplex Facility
Lifespan-Rhode Island Hospital
Behavioral Phenotyping - Morris Water Maze

Fabricated in house Opaque white pool with platform for behavioral swim test.
Multiplex Facility
Lifespan-Rhode Island Hospital
Biospecimen Banking - Freezer

HHP Barcoding InstrumentBarcode samples for identification. File Pro software.
Multiplex Facility
Lifespan-Rhode Island Hospital
Centrifuge

Beckman- Coulter Allegra 64R Refrigerated CentrifugeFor use with 50 mL conical tubes.
Multiplex Facility
Lifespan-Rhode Island Hospital
Cryostat

Leica CryostatFrozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.
Multiplex Facility
Lifespan-Rhode Island Hospital
Disrupter

Siegen Tissue LyserDisrupts multiple biological samples through high speed shaking in plastic tubes with steel, tungsten carbide, or glass beads. Up to 48 samples can be processed simultaneously.
Multiplex Facility
Lifespan-Rhode Island Hospital
Imaging System

Applied Scientific Instrumentation MS-1000XY stage designed to provide a high resolution, and highly repeatable, means of controlling the X and Y position of a microscope stage
Multiplex Facility
Lifespan-Rhode Island Hospital
Imaging System - Camera

Olympus U-CMAD3 cameraConnected to Olympus Inverted CKX31 Fluorescent Microscope. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Multiplex Facility
Lifespan-Rhode Island Hospital
Imaging System - Camera

Sony 3CCD Exwave HAD Digital CameraConnected to Olympus BX60. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Multiplex Facility
Lifespan-Rhode Island Hospital
Imaging System - Camera

Stereologer 2001/3" type DSP 3-CCD PAL color video camera with improved camera sensitivity (F8 at 2000 lx). Resolution of 800 TVL and a high S/N ratio of 61 dB.
Multiplex Facility
Lifespan-Rhode Island Hospital
Microplate Reader

Molecular Dynamics M5 SpectracountCross talk (96-well): 3X 10-5, sensitivity: <20 attomol ATP per well, <0.2 firely luciferase per well, spectral range: 380-630 nm.
Multiplex Facility
Lifespan-Rhode Island Hospital
Microplate Reader

Packard-Perkin Elmer TopcountAnalysis of cell proliferation, receptor binding assays, solid phase RIA/LIA, reporter gene assays, 51Cr release assays, HPLC fraction analysis, scintillation proximity assays, etc.
Multiplex Facility
Lifespan-Rhode Island Hospital
Microplate Reader

Molecular Devices UV Max Microplate Reader96-wellplate reader. Spectral range: 405-630 nm.
Multiplex Facility
Lifespan-Rhode Island Hospital
Microscope

Olympus BX60High-resolution digital pictures using conventional manual filter cubes or more versatile automated filter wheels, and can superimpose multi-color pictures
Multiplex Facility
Lifespan-Rhode Island Hospital
Microscope

Olympus Inverted CKX31 Fluorescent MicroscopeInverted microscope with the capability of a fluorescence illuminator for GFP; documentation of images with digital imaging and video monitoring. Use for petri dishes, culture flasks, and multi-well plates.
Multiplex Facility
Lifespan-Rhode Island Hospital
Microscope

Olympus Inverted Fluorescent microscopeFN22. 9mm stroke, coaxial coarse and fine focusing knobs. Long working distance universal condenser.
Multiplex Facility
Lifespan-Rhode Island Hospital
PCR Thermal Cycler

Roche Lightcycler 4810Exchangeable 96 or 384 multiwell plate format. Ideal for multiplexing and automated workflows. Provides various methods for gene detection, gene expression analysis, genetic variation analysis and array data validation.
Multiplex Facility
Lifespan-Rhode Island Hospital
Robotic Workstation - DNA Extraction

QUIAGEN Biorobot EZ1Fully automated purification of genomic DNA from human whole blood and viral nucleic acids from serum or plasma samples.
Multiplex Facility
Lifespan-Rhode Island Hospital
Robotic Workstation - Pipetting

Eppendorf EpMotion 5070Automated pipetting. Four deck positions can hold tips, reagent reservoirs, single tubes, tube racks, micro-plates, or PCR plates with up to 384 wells. Suited for serial dilutions, reagent distribution, transfer from tubes to plates and normalization.
Multiplex Facility
Lifespan-Rhode Island Hospital
Robotic Workstation - Pipetting

Tecan Genesis 200 RobotAutomated robot for pipetting tasks. Two arms- the LiHa (liquid handler) and the RoMa (robot manipulator). LiHa- conductivity-sensing 8-channel pipetting arm dispenses volumes of 5-1000 µL; RoMa- manipulating arm picks up and moves objects on the workstation.
Multiplex Facility
Lifespan-Rhode Island Hospital
Spectrophotometer

Thermo Scientific NanoDrop 2000Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter.
Multiplex Facility
Lifespan-Rhode Island Hospital
Suspension Array

Luminex MagpixReads magnetic bead–based immunoassays. Automated reading of 96-well plates (~60 min/plate). Multiplex analysis of up to 50 biomolecules in a single sample.
Multiplex Facility
Lifespan-Rhode Island Hospital
Suspension Array

Bio-Rad BioPlex 100Automated reading of 96-well plates, up to 9,600 data points in about 35 min. Multiplex analysis of up to 100 biomolecules in a single sample via suspension array.
Multiplex Facility
Lifespan-Rhode Island Hospital
Suspension Array System

Bio-Rad Vacuum manifoldVacuum purification platform for single 96-well plates or individual luer-ended spin columns. Compatible with Bio-Plex 200 suspension array system.
NMR Facility
Brown University
Nuclear Magnetic Resonance (NMR) Spectrometer

Bruker 300 Avance z-BBI probe, (least sensitivte 1H and indirect detection to all broadband nuclei)
NMR Facility
Brown University
Nuclear Magnetic Resonance (NMR) Spectrometer

Bruker 600 Avance III HD Ascendz-BBFO probe for all nuclei (most sensitive for all nuclei)
NMR Facility
Brown University
Nuclear Magnetic Resonance (NMR) Spectrometer

Bruker 400 Avance III Ultra-Shield z-TXI probe, (2nd best sensitivity for 1H and indirect detection on 13C/15N)
NMR Facility
Brown University
Nuclear Magnetic Resonance (NMR) Spectrometer

Bruker 400 Avance Ultra-Shield z-BBO probe, (2nd best sensitivity for broadband nuclei)
PC - Albertus Magnus Hall Labs
Providence College
Environmental Chamber

Contact: Maia Bailey

Percival Scientific 2 units
PC - Albertus Magnus Hall Labs
Providence College
Environmental Chamber

Contact: Maia Bailey

Percival Scientific, AR-22L Growth ChamberFor Arabidopsis
PC - Albertus Magnus Hall Labs
Providence College
Imaging - Camera

Contact: Pat Ewanchuk

Fastec HiSpec1, Low-Light High-Speed CameraInnovative Low-Light High-Speed Camera. Monochrome with 2GB Memory, C-Mount, includes ImageBLITZ Auto Trigger, Burst Trigger Mode, Multi- Sequence Record Mode (1280 x 1024 at 506fps) 2 Units
PC - Albertus Magnus Hall Labs
Providence College
Microscope - Electron

Contact: Joe DeGiorgis

Philips EM-300 Transmission Electron Microscope (TEM)Transmission electron microscopy
PC - Albertus Magnus Hall Labs
Providence College
Laboratory - Prep Lab

Contact: Joe DeGiorgis

Electron Microscopy Prep LabLaboratory space for preparing samples for electron microscopy
PC - Albertus Magnus Hall Labs
Providence College
Microscope - Electron

Contact: Joe DeGiorgis

Amray-1000 Scanning Electron Microscope (SEM)Scanning Electron Microscope equipped with EDEX for elemental analysis and a digital imaging system, a Zeiss Axiophot equipped for bright field, dark field, DIC and fluorescence microscopy with a digital imaging system
PC - Albertus Magnus Hall Labs
Providence College
Microtome

Contact: Joe DeGiorgis

Porter-Blum MT-2B UltramicrotomePorter-Blum MT-2B UltraMicrotomes, 2 Units
PC - Albertus Magnus Hall Labs
Providence College
Aquatic System

Contact: Pat Ewanchuk

Aquatic Habitats Glass Tank System and Life Support Controller Glass tank system and life support controller with low water level protection (18-10 gallon tanks)
PC - Hickey Hall Labs
Providence College
DNA Sequencer

Contact: Elisabeth Arevalo

ABI Prism 3100 Genetic AnalyzerUsed for DNA sequencing and fragment analysis. The ABI PRISM 3100 Genetic Analyzer is an automated capillary electrophoresis system that can separate, detect, and analyze up to 16 capillaries of fluorescently labeled DNA fragments in one run.
PC - Hickey Hall Labs
Providence College
PCR Thermal Cycler

Contact: Charles Toth

Stratagene Mx3000p Real-time PCR Thermal CyclerThis instrument is available for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Agilent’s qPCR software, MxPro, provides users with an intuitive interface, quick experiment design, powerful data analysis and easy report generation
PC - Hickey Hall Labs
Providence College
Fluorescence Activated Cell Sorter (FACS)

Contact: Charles Toth

Flow Cytometer- Accuri C6The BD Accuri C6 is a personal flow cytometer that is easy to use, simple to maintain, and affordable.
PC - Hickey Hall Labs
Providence College
Cold Room

Contact: Charles Toth

Walk-In Cold Room
PC - Hickey Hall Labs
Providence College
Analyzer - Cell Metabolism

Contact: Marla Tipping

Seahorse Biosciencies, XFe Extracellular Flux Analyzers, XFe96Platform for metabolic assays that simultaneously measures the two major energy producing pathways of the cell - mitochondrial respiration and glycolysis - in a microplate, in real-time.
PC - Hickey Hall Labs
Providence College
Laboratory - Tissue Culture

Contact: Charles Toth

Tissue Culture LaboratorySpace and instrumentation for tissue culture preparation
PC - Hickey Hall Labs
Providence College
Imaging System - Gel Imager

Contact: Yinsheng Wan

Licor Odyssey IR (Infrared) Imaging SystemInstrumentation for quantitating western blots.
PC - Hickey Hall Labs
Providence College
Fluorescence Activated Cell Sorter (FACS)

Contact: Nicanor Austriaco

Cellometer Vision Image CytometryThe Vision CBA System combines the simplicity of image cytometry with the power of flow analysis software to offer user-friendly cell-based assays
PC - Hickey Hall Labs
Providence College
Spectrophotometer

Contact: Charles Toth

Thermo Scientific NanoDropUV/VIS
PC - Sowa Hall Labs
Providence College
Microscope

Contact: Joe DeGiorgis

Zeiss LMS 700 Flexible Confocal Microscope Performs fluorescence measurements, creates optical sections of samples and combines them into 3D image stacks.
Plant Environmental Center
Brown University
Greenhouse, Plant Environmental Center

Contact: Chris Claussen

Plant environmental center with six separate, computer controlled rooms where conditions like lighting, temperature, and humidity can be fine tuned; an additional 17 controlled plant growth environments provided by growth chambers (15) and walk-in growth rooms (2)A plant environmental center with a suite of supporting facilities, including a classroom, a 'headhouse' for potting and other prep work,and growth chambers for plants.
Proteomics Core
Lifespan-Rhode Island Hospital
Bioanalyzer

Agilent Bioanalyzer 2100Microfluidics platform (electrophoresis and flow cytometry) for sizing, quantification, and QC of DNA, RNA, proteins, and cells. Sample size= 1-4 microliters.
Proteomics Core
Lifespan-Rhode Island Hospital
Bioinformatics Analysis - HD Examiner DXMS analysis software

Software: HD Examiner DXMS Analysis Software to analyze peptide search results from SEQUEST HTML, Mascot XML, Proteome Discoverer .xls, pepXML, or generic tabular data. Both low- and high-resolution MS data.
Proteomics Core
Lifespan-Rhode Island Hospital
Bioinformatics Analysis - MASCOT

Software: Matrix Science MASCOT Search EngineSoftware for MS data analysis through statistical evaluation of matches between observed and projected peptide fragments.
Proteomics Core
Lifespan-Rhode Island Hospital
Bioinformatics Analysis - ProteoIQ

Software: NuSep ProteoIQ Mass Spec Data AnalysisSoftware for post-analysis of MASCOT results. Protein and peptide probabilities generated and protein relative quantitation is performed by spectral counting. Normalized and with standard deviations.
Proteomics Core
Lifespan-Rhode Island Hospital
Bioinformatics Analysis - Workstation

Hardware: HP HPZ 800 Workstation Software (2 workstations available) used in conjunction with ProteoIQ, DXMS, MASCOT analysis.
Proteomics Core
Lifespan-Rhode Island Hospital
Gel Imager

Bio-Rad Molecular Imager VersaDocQuantitative digital imaging system for single or multi-color images. Includes multiplexed samples (1-D or 2-D gels), chemiluminescent and chemifluorescent blots, and microplates.
Proteomics Core
Lifespan-Rhode Island Hospital
High Performance Liquid Chromatography (HPLC)

Bio-Rad DuoFlow Biologic HPLCMedium-pressure chromatography system. 100/120 V, F10 workstation, mixer, AVR7-3 valve, UV detector with flow cell and filters. Flow rate= 0.01–10 ml/min.
Proteomics Core
Lifespan-Rhode Island Hospital
High Performance Liquid Chromatography (HPLC)

Transgenomic Wave DHPLC SystemDetect mutations/ polymorphisms by Denaturing High Performance Liquid Chromatography (DHPLC). Uses SURVEYOR nuclease cleavage. Identifies single nucleotide polymorphisms (SNPs) or small insertions/ deletions.
Proteomics Core
Lifespan-Rhode Island Hospital
High Performance Liquid Chromatography (HPLC)

Dionex UltiMate3000 Nano HPLCSingle gradient and x2 dual configurations. Eluted directly into MS. Min detection= fmole; Min flow rate= 20 nL/min; Max pressure = 800 bar.
Proteomics Core
Lifespan-Rhode Island Hospital
Liquid Chromatography- Mass Spectrometer (LC-MS)

Thermo Scientific Q Exactive Mass Spectrometer Benchtop LC-MS/MS. Combination of high-performance quadrupole with high resolution, accurate-mass (HR/AM) Orbitrap. Max resolving power= 140,000; max scan speed= 12Hz, Intra-scan dynamic range > 5000:, Quadrupole mass filter.
Proteomics Core
Lifespan-Rhode Island Hospital
Mass Spectrometer

AB SCIEX QSTAR XL Mass SpectrometerIdentification and analysis of protein structure/conformational change by deuterium exchange mass spectrometry (DXMS). LC/MS/MS- Ionization by MALDI or ESI after HPLC (Dionex) and analyzed by quadrupole and TOF.
Proteomics Core
Lifespan-Rhode Island Hospital
Mass Spectrometer

Brucker UltrafleXtreme: Imaging Mass SpectrometryMALDI-IMS for tissue imaging, intact proteins analysis, protein spatial distribution, glycoproteomics, or biologics (1-2000 Hz repetition rates) of non-injured vs. injured tissues. MALDI/TOF/TOF analysis for proteomic profiling. Minimum diameter = 10 microns.
Proteomics Core
Lifespan-Rhode Island Hospital
Robotic Workstation -Liquid Handler

Perkin Elmer JANUS Automated Workstation Automated Sterile Liquid Handler. 2 arm system, with 4- or 8-tip arm plus a 96/384 MDT arm. Arms include 4-tip or 8-tip dispense arms for transfer from tubes to vials to plates.
Proteomics Core
Lifespan-Rhode Island Hospital
Spectrophotometer

Amersham Biosciences UV/Visible Spectrophotometer Ultrospec 1100Wavelength range: 200–900 nm. Spectral bandwidth: 5 nm Wavelength accuracy ± 2 nm. Wavelength reproducibility: ± 0.5 nm.
Proteomics Core
Lifespan-Rhode Island Hospital
Spectrophotometer

Thermo Scientific NanoDrop 2000Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter.
Proteomics Core
Lifespan-Rhode Island Hospital
Suspension Array System

Bruker ImagePrep matrix sprayerMatrix deposition device for MALDI Imaging. Average droplet size ? 20 microns, all droplet dia. are < 50 microns. Lateral resolution of 50 microns in tissue.
Proteomics Core
Lifespan-Rhode Island Hospital
Suspension Array System

LC Packings ProBot LC/MALDI spotterNano-LC/MALDI-MS interface. Robotic system for MALDI spotting/fraction collection. On-line collection of nL- and microliter-fractions from nano/capillary LC systems on sample carriers (MALDI targets, PVDF membranes, 96, 384, or 1536 well plates, or microchip structures). Two well plate capacity. Dual-collection mode for fraction splitting over two different sample carriers.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - 1D SDS PAGE Coomasie

ServiceService to provide 1D gel (SDS-PAGE) Coomasie Staining.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - 1D SDS PAGE Silver Stain

ServiceService to provide 1D gel (SDS-PAGE) Silver Stain MS compatible.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Bioanalyzer

ServiceService to provide Agilent Bioanalyzer (Protein 80).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Bioanalyzer

ServiceService to provide Service to provide Agilent Bioanalyzer (Protein 250).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Bioanalyzer

ServiceService to provide Service to provide Agilent Bioanalyzer (Protein 230).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Deuterium Exchange MS (DXMS)

ServiceService to provide Deuterium Exchange MS (DXMS)- Data analysis and interpretation
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Deuterium Exchange MS (DXMS)

ServiceService to provide Deuterium Exchange MS (DXMS)- Digestion Optimization (includes duplicates)
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Deuterium Exchange MS (DXMS)

ServiceService to provide Deuterium Exchange MS (DXMS)- Experimental Setup
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Deuterium Exchange MS (DXMS)

ServiceService to provide Deuterium Exchange MS (DXMS)- On-exchange time course experiment (includes duplicates)
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Deuterium Exchange MS (DXMS)

ServiceService to provide Deuterium Exchange MS (DXMS)- Triplicates
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Gel Imaging

ServiceService to provide Gel imaging by VersaDoc.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - MALDI Imaging MS

ServiceService to provide MALDI Imaging MS.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Mass Spectrometry

ServiceService to provide Imaging Mass Spectrometry Data Analysis.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein Determination

ServiceService to provide Protein Determination (BCA assay).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein Extraction

ServiceService to provide ReadyPrep Protein Extraction Kit (Sequential Extraction).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein Extraction

ServiceService to provide ReadyPrep Protein Extraction Kit (Total Protein).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein In-Gel Digestion

ServiceService to provide In-gel digestion LC/MS analysis and protein database search.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein In-Solution Digestion

ServiceService to provide In-solution digestion LC/MS analysis and protein database search.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein Quantification

ServiceService to provide Data interpretation and protein quantification.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Protein Sample Clean-up

ServiceService to provide ReadyPrep 2D Cleanup Kit.
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Proteomics Project Consultation

ServiceService to provide Project consultation with the Director of Proteomics – Subsequent Consultation
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - Proteomics Project Consultation

ServiceService to provide Project consultation with the Director of Proteomics – Initial Consultation
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - WAVE DNA

ServiceService to provide WAVE (DNA).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - WAVE PCR

ServiceService to provide WAVE (PCR product).
Proteomics Core
Lifespan-Rhode Island Hospital
Technical Assistance - WAVE Tissue

ServiceService to provide WAVE (tissue).
Proteomics Facility
Brown University
Bioinformatics Analysis - MASCOT

Software: Matrix Science MASCOT Search EngineSoftware for protein identification, characterization and quantitation (v.2.4.1)
Proteomics Facility
Brown University
Bioinformatics Analysis - PEAKS Studio

Software: Bioinformatics Solutions Inc. PEAKS Studio Software for de novo sequencing and database searching (v.6.0)
Proteomics Facility
Brown University
Bioinformatics Analysis - ProSight PC

Software: Thermo Scientific ProSight PC Software for "top-down" proteomics analysis (v.2.0)
Proteomics Facility
Brown University
Bioinformatics Analysis - ProteoIQ

Software: NuSep ProteoIQ Mass Spec Data AnalysisSoftware for mass spectrometry proteomic analysis (v.2.61)
Proteomics Facility
Brown University
Bioinformatics Analysis - Proteome Discoverer

Software: Thermo Scientific Proteome Discoverer Software for database searching and protein quantitation (v.1.3)
Proteomics Facility
Brown University
Calorimeter

Microcal Isothermal Titration 200 (ITC)Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
Proteomics Facility
Brown University
Calorimeter

Microcal VP Differential Scanning (DSC)Measurement of heat changes that occur in biomolecules during controlled increase or decrease in temperature.
Proteomics Facility
Brown University
Fermenter

Infors MiniforA bench-top (1-5 L) laboratory fermenter and bioreactor for bacteria and yeast.
Proteomics Facility
Brown University
Fluorometer - Spectrofluorometer

Horiba Jobin Yvon FluoroMax-4Fluorescence detection. A heated cell allows temperature studies.
Proteomics Facility
Brown University
High Performance Liquid Chromatography - Ultra High (UHPLC)

AB SCIEX Eksigent nanoLC-Ultra 2D+ UHPLCIsocratic low flow rates of 1-20 microliter/min and dual nanoflow pumps for 50-1000 nL/min. A novel pumping system eliminates the need for flow splitting, providing excellent run-to-run reproducibility. It serves as the "front end" for nanoflow LC/MS.
Proteomics Facility
Brown University
High Performance Liquid Chromatography (HPLC)

Agilent 1200 HPLC SystemHigh performance liquid chromatography system with quaternary pump and thermostatted autosampler serves as the "front end" for nanoflow LC/MS.
Proteomics Facility
Brown University
High Performance Liquid Chromatography (HPLC)

Agilent 1200 HPLC SystemHigh performance liquid chromatography system with: quaternary pump, thermostatted autosampler, thermostatted fraction collector, and a multi-wavelength UV/Vis detector. It can be used for analytical detection of biomolecules and/or their purification.
Proteomics Facility
Brown University
Liquid Chromatography System

GE Healthcare AktaPrime Plus The ÄKTA Prime Plus is a low pressure chromatography system that performs simple purifications of tagged and untagged proteins.
Proteomics Facility
Brown University
Mass Spectrometer

Thermo Scientific LTQ Orbitrap Velos Peptide/protein identification in complex samples, molecular weight determination of intact proteins, post translational modification analysis (PTM), improved quantitation of peptides in label-free, SILAC, iTRAQ or TMT experiments.
Proteomics Facility
Brown University
Spectrophotometer

JASCO J-815 Circular Dichroism (CD) SpectrometerProtein folding studies, Protein conformational studies, DNA/RNA interactions, Enzyme kinetics, Purity testing of optically active substances, quantitative analysis of pharmaceuticals, natural products chemistry, biochemistry and macromolecules, rapid scanning (time resolved) experiments. Peltier device for temperature studies.
Proteomics Facility
Brown University
Spectrophotometer

Thermo Scientific NanoDrop 8000 A full spectral microvolume (microliter) UV-Vis analysis spectrophotometer for measuring DNA, RNA, and protein of 8 samples simultaneously.
Proteomics Facility
Brown University
Surface Plasmon Resonance (SPR) Sensor

General Electric Healthcare Biosciencees Biacore X 100Label-free protein interaction analysis provides unique and comprehensive data on the interactions between biomolecules. Performs quantitative kinetic analysis (rate constants), quantitative determination of affinity constants, determination of binding specificity (yes/no), and concentration analysis.
Proteomics Facility
Brown University
Technical Assistance - Protein Determination

ServiceService to determine protein concentration using Life Technologies QuBit, Thermo Scientific Pierce Protein 660, or Thermo Scientific Micro BCA
Proteomics Facility
Brown University
Technical Assistance - Protein In-Gel Digestion

ServiceService to destain, reduce and alkylate, enzyme digest and extract peptides from a gel
Proteomics Facility
Brown University
Technical Assistance - Protein In-Solution Digestion

ServiceService to denature, reduce and alkylate and enzyme digest proteins in solution
Proteomics Facility
Brown University
Technical Assistance - Protein Sample Clean-up

ServiceService to remove protein solution contaminants and/or concentrate protein samples using Bio-Rad ReadyPrep 2D,Thermo C18 Spin, Millipore ZipTip
Proteomics Facility
Brown University
Technical Assistance - Proteomics Project Consultation

ServiceService to provide Proteomics Technical Assistance
Proteomics Facility
Brown University
Technical Assistance - Proteomics Training

ServiceService to provide Proteomics Training
Research Facility
The Providence VA Medical Center
Autoclave

Tuttnauer Equipment: consumable sterilization
Research Facility
The Providence VA Medical Center
Behavioral Phenotyping - Eye Tracking System

TobiiUsed to track eye movement
Research Facility
The Providence VA Medical Center
Bioanalyzer

Agilent BioanalyzerDNA size & quantification (quality check for downstream analyses, i.e. next gen sequencing)
Research Facility
The Providence VA Medical Center
Capillary Electrophoresis

Applied BiosystemsAnalyze fragment length polymorphisms (96/384 format) (2)
Research Facility
The Providence VA Medical Center
Centrifuge

Eppendorf Refrigerated Centrifuge Alcohol precipitation
Research Facility
The Providence VA Medical Center
Centrifuge

EppendorfFor centrifuging 96/384 plates
Research Facility
The Providence VA Medical Center
DNA Sequencer

Ion Torrent/Life Technologies Personal Genome MachineNext Generation Sequencer
Research Facility
The Providence VA Medical Center
Mass Spectrometer

Sequenomhigh throughput SNP genotyping, epigenetics
Research Facility
The Providence VA Medical Center
Microarray Scanner

Illumina HiScanWhole-genome genotyping, gene expression analysis, methylation analysis
Research Facility
The Providence VA Medical Center
Microplate Reader

BioTekDNA quantification
Research Facility
The Providence VA Medical Center
Microplate Reader

Fluidigm End Point Reader High throughput SNP genotyping
Research Facility
The Providence VA Medical Center
PCR Thermal Cycler

Applied Biosystems384 well DNA amplification for downstream analysis (i.e. sequenom processes) (2 units)
Research Facility
The Providence VA Medical Center
PCR Thermal Cycler

Applied Biosystems96 well DNA amplification for downstream analysis (i.e. fragment length polymorphisms)(2 units)
Research Facility
The Providence VA Medical Center
PCR Thermal Cycler

Applied Biosystems Real Time PCRAnalyze single nucleotide polymorphisms (single locus)
Research Facility
The Providence VA Medical Center
PCR Thermal Cycler

Applied Biosystems Real Time PCRAnalyze single nucleotide polymorphisms (single locus)
Research Facility
The Providence VA Medical Center
Robotic Workstation - DNA Extraction

Chemagen/Perkin Elmer Magnetic Separation ModuleDNA extraction from blood & saliva
Research Facility
The Providence VA Medical Center
Robotic Workstation - Liquid Handler

Sequenom Liquid Handler Transfers PCR chemistries to samples (96/384 format)
Research Facility
The Providence VA Medical Center
Robotic Workstation - Liquid Handler

Sequenom NanodispenserDispenses PCR product to Sequenom chip
Research Facility
The Providence VA Medical Center
Robotic Workstation - Sample Preparation

Iontorrent/Life Technologies Enrichment SystemSimplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.
Research Facility
The Providence VA Medical Center
Robotic Workstation - Sample Preparation

Iontorrent/Life Technologies One TouchSimplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.
Research Facility
The Providence VA Medical Center
Robotic Workstation - Sample Processing

Thermo Scientific Cap-it-AllCaps tubes to the optimal torque to maintain sample integrity and provide a hands free method to capping and decapping tubes quickly and easily.
Research Facility
The Providence VA Medical Center
Robotic Workstation -Liquid Handler

Beckman Coulter Lab Automation WorkstationAutomated liquid handler
Research Facility
The Providence VA Medical Center
Spectrophotometer

Thermo Scientific NanoDropDNA quantification
Rhode Island BioBank
Brown University
Bioinformatics Analysis - Freezerworks

Software: FreezerworksSample management software
Rhode Island BioBank
Brown University
Biospecimen Banking

Service Service to store biospecimens at -80 degrees, 4 degrees and in liquid nitrogen. All equipment is connected to back–up generator power and monitored 24/7 by a Rees alarm system.
Rhode Island BioBank
Brown University
Biospecimen Banking - Freezer System

Taylor Wharton LABS 40K Liquid Nitrogen Storage SystemLiquid nitrogen storage system connected to back–up generator power and monitored 24/7 by a Rees alarm system
Rhode Island BioBank
Brown University
Robotic Workstation - Sample Preparation

Qiagen QiaCubeDNA, RNA or Protein Purification
Rhode Island Nuclear Science Center
Rhode Island State Agency
Reactor, Research and Test

Contact: Jeff Davis

2 Mega-Watt, light water cooled, pool type reactorNeutron and gamma irradiation, as well as analysis
RIC - Fogarty Life Sciences Labs
Rhode Island College
Knifemaker

Contact: Breea Govenar

LKB 7800 KnifemakerSlide/Sample Preparation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microtome

Contact: Breea Govenar

Leica RM2165 Motorized Rotary MicrotomeSlide/Sample Preparation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microtome

Contact: Breea Govenar

TBS Microtome plus CryostatSlide/Sample Preparation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

American Optical Series 10 Fluorescence MicrostartMicroscopy course
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

Nikon E600 Epifluorescence with DIC/Phase and digital cameraResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

Olympus CKS41 Inverted MicroscopeTissue culture general use
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

Olympus Compound Light MicroscopeGeneral use
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

Olympus FluoView 1000 Laser Scanning Confocal MicroscopeResearch and Microscopy course
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

Olympus Inverted Epifluorescence Microscope with digital cameraTissue culture/Research
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microscope

Contact: Breea Govenar

Zeiss SteREO discovery V8 Microscope with Digital CameraResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Wet Lab / Aquarium room

Contact: Breea Govenar

Aquaria and related equipmentResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Autoclave

Contact: Breea Govenar

AutoclaveMicrobiology/Research
RIC - Fogarty Life Sciences Labs
Rhode Island College
Biological Safety Cabinet

Contact: Breea Govenar

Labconco class II Biological Safety CabinetUsed for tissue culture
RIC - Fogarty Life Sciences Labs
Rhode Island College
Biological Safety Cabinet

Contact: Breea Govenar

Sterile laminar flow hoodMicrobiology prep
RIC - Fogarty Life Sciences Labs
Rhode Island College
Centrifuge

Contact: Breea Govenar

Eppendorf 5810R Refrigerated CentrifugeUsed for tissue culture
RIC - Fogarty Life Sciences Labs
Rhode Island College
Centrifuge

Contact: Breea Govenar

Sorvall Discovery M120SE Mini UltracentrifugeResearch/Cell fractionation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Centrifuge

Contact: Breea Govenar

Sorvall Superspeed RC2 CentrifugeGeneral use
RIC - Fogarty Life Sciences Labs
Rhode Island College
Centrifuge

Contact: Breea Govenar

Sorvall Superspeed RC5 Plus CentrifugeResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Centrifuge

Contact: Breea Govenar

Thermo IEC Centra CL3R Refrigerated CentrifugeGenetics and Cell & Molec courses
RIC - Fogarty Life Sciences Labs
Rhode Island College
Cold Room

Contact: Breea Govenar

Walk-In Cold RoomLarge cold room for experimentation and storage
RIC - Fogarty Life Sciences Labs
Rhode Island College
Dishwasher

Contact: Breea Govenar

DishwasherMicrobiology/Research
RIC - Fogarty Life Sciences Labs
Rhode Island College
Disrupter

Contact: Breea Govenar

French Pressure Cell PressResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Disrupter

Contact: Breea Govenar

Polytron Tissue GrinderSlide/Sample Preparation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Disrupter

Contact: Breea Govenar

SonicatorGeneral use and research
RIC - Fogarty Life Sciences Labs
Rhode Island College
Disrupter

Contact: Breea Govenar

Sonicator with cupResearch and graduate courses
RIC - Fogarty Life Sciences Labs
Rhode Island College
Electroporation System

Contact: Breea Govenar

BioRad Micropulser ElectroporatorResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Freeze Dryer

Contact: Breea Govenar

ATMO VAC 5009 freeze dryerSlide/Sample Preparation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Freezer

Contact: Breea Govenar

Thermolyne Liquid Nitrogen cryogenic storage systemCell storage
RIC - Fogarty Life Sciences Labs
Rhode Island College
Freezer

Contact: Breea Govenar

Ultralow FreezerUsed for freezing biological samples, 6 units
RIC - Fogarty Life Sciences Labs
Rhode Island College
Gel Imager

Contact: Breea Govenar

InGenius Syngene Gel Documentation SystemResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Ice Machine

Contact: Breea Govenar

Ice MachineGeneral use
RIC - Fogarty Life Sciences Labs
Rhode Island College
Imaging System - Dark Room

Contact: Breea Govenar

Imaging System - Dark RoomGel imaging and analysis
RIC - Fogarty Life Sciences Labs
Rhode Island College
Incubator

Contact: Breea Govenar

Non CO2 IncubatorUsed for tissue culture
RIC - Fogarty Life Sciences Labs
Rhode Island College
Incubator

Contact: Breea Govenar

Thermo CO2 Incubators Used for tissue culture, 2 units
RIC - Fogarty Life Sciences Labs
Rhode Island College
Incubator

Contact: Breea Govenar

Refrigerated IncubatorUsed for tissue culture
RIC - Fogarty Life Sciences Labs
Rhode Island College
Laboratory - Tissue Culture

Contact: Breea Govenar

Tissue Culture RoomA room outfitted with tissue culture instrumentation
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microplate Reader

Contact: Breea Govenar

Lenovo Automated Plate ReaderResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Microplate Reader

Contact: Breea Govenar

Thermo Labsystems Multiskan MMCC/340 plate readerResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Oven

Contact: Breea Govenar

Drying OvenGeneral use
RIC - Fogarty Life Sciences Labs
Rhode Island College
PCR Thermal Cycler

Contact: Breea Govenar

BioRad IQS Real time PCR thermocyclerResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
PCR Thermal Cycler

Contact: Breea Govenar

Eppendorf Gradient Mastercycler PCR instrumentation, 2 units
RIC - Fogarty Life Sciences Labs
Rhode Island College
Shakers

Contact: Breea Govenar

Incubator/ShakersMultiple units
RIC - Fogarty Life Sciences Labs
Rhode Island College
Spectrophotometer

Contact: Breea Govenar

BioRad SmartSpec PlusResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Spectrophotometer

Contact: Breea Govenar

Eppendorf BiophotometerGectrophotometerseral use
RIC - Fogarty Life Sciences Labs
Rhode Island College
Spectrophotometer

Contact: Breea Govenar

Spectronic 21 D UV/VISResearch
RIC - Fogarty Life Sciences Labs
Rhode Island College
Spectrophotometer

Contact: Breea Govenar

Therm Spectronic Genesys UV/VIS Scanning Research, 6 units
RIC - Fogarty Life Sciences Labs
Rhode Island College
Spectrophotometer

Contact: Breea Govenar

Thermo Scientific NanoDrop ND-1000 UV/VIS, 2 units
RIC - Fogarty Life Sciences Labs
Rhode Island College
Water Purification System

Contact: Breea Govenar

Barnstead Still Water PurifierGeneral use for teaching labs
RIC - Fogarty Life Sciences Labs
Rhode Island College
Water Purification System

Contact: Breea Govenar

Millipore DirectQ (X2)Tissue culture
RIC - Fogarty Life Sciences Labs
Rhode Island College
Water Purification System

Contact: Breea Govenar

Millipore NanoPure Diamond 2nd floor research use
RIC - Fogarty Life Sciences Labs
Rhode Island College
Imaging System - X-ray Film

Contact: Breea Govenar

X-ray film processorBlot imaging
RISD Media Resources
Rhode Island School of Design
Imaging System - Audio|Visual

Kodak zi 10 Video Camera (8 units)Portable HD pocket camcorder, batteries, adaptor cables, cases, accessories
RISD Media Resources
Rhode Island School of Design
Imaging System - Audio|Visual

H4N ZOOM Audio Recorder (5 Units)High performance portable digital audio recorder, batteries, adaptor cables, cases, accessories
RISD Media Resources
Rhode Island School of Design
Imaging System - Audio|Visual

ZOOM Q3 Video Camera (7 Units)Portable palm camcorder, batteries, adaptor cables, cases, accessories
RISD Media Resources
Rhode Island School of Design
Imaging System - Audio|Visual

EPS-SonyPMWEX1R-01 (2 Units)High performance HD CMOS solid state video camera, batteries, portable hard drive, adaptor cables, cases, studio lighting equipment, accessories
RISD Nature Lab
Rhode Island School of Design
Aquatic System

Marine Ecological Habitats Closed-System Aquarium560 L closed-system recirculating marine holding tanks with temperature control (2 units)
RISD Nature Lab
Rhode Island School of Design
Microscope

Phenom G2Pro Scanning Electron Microscope (SEM)Desktop Scanning Electron Microscope with ProSuite tiling and remote access software
RISD Nature Lab
Rhode Island School of Design
Microscope

Olympus SZX16 StereomicroscopeLight microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging software
RISD Nature Lab
Rhode Island School of Design
Microscope

Olympus IX51 Inverted Fluorescent/Brightfield Microscope Fluorescence/brightfield microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging software
RISD Nature Lab
Rhode Island School of Design
Microscope

Olympus CH30 Upright Light Microscope Upright light microscope with 3.3 MP Jenoptik digital camera, Canon Vixia HFS20 HD video camera, computer workstation, graphics and imaging software (2 units)
RISD Nature Lab
Rhode Island School of Design
Microscope

Olympus SZ40 StereomicroscopeLight microscope with 3.3 MP Jenoptik digital camera, computer workstation, graphics and imaging software
RISD Nature Lab
Rhode Island School of Design
Microscope

Olympus SZ30 Stereomicroscope Light microscope with LED illuminator (24 units)
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping

Service A high-throughput behavioral testing facility that integrates high-level computer vision, computer learning, and custom built hardware solutions with behavioral testing to automate tracking, cataloging, and analysis of both home cage behavior and standard rodent testing paradigms to characterize preclinical models of disorders, test novel pharmacological and genetic rescue strategies in rodent models.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - 4x Operant Chambers

Med AssociatesCan be used to train mice on operant tasks (equipped with water dipper system) for reinforcement learning, as well as grid floor and speaker system for fear conditioning experiments
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - 2x Open Field

Fabricated in house Used to monitor activity in novel settings and to assay anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - 3-chamber Social Preference

Fabricated in house Used to assess a mouse preference for being in close proximity to another mouse.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Barnes Maze

Fabricated in house Used to assess spatial learning and memory in rodent models.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Cold Swim Stress

Fabricated in house Used to monitor anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Cylinder Test

Fabricated in house Used to assess motor coordination and balance
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Early Life Drug Exposure

Fabricated in house Used to assess the impact of pharmacological agents on cognitive, motor, and affective development.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Early Life Stress (Maternal Bedding Restriction)

Fabricated in house Used to induce later development of anxiety and depressive-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Early Life Stress (Variable shock)

Fabricated in house Used to assess elevated levels of anxiety and depressive-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Elevated Zero Maze

Fabricated in house Used to monitor rodent anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Estrous Cycling (Vaginal Cytology)

Fabricated in house Used to assess stage of estrous cycle of rodent models.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Exercise Induced Anorexia

Fabricated in house Use of running and food restriction to induce lower levels of body fat and food consumption
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Five Lane Forced Treadmill

Columbus InstrumentsUsed to induce exercise stress to assess motor fatigue and locomotor abilities.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Five Lane Rotarod

Med AssociatesUsed to assess motor pattern learning and coordination.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Flurothyl Induced Seizures

Fabricated in house Used to assess monitored induction of tonic and clonic seizures
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Forced Swim

Fabricated in house Used to assess depressive-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Formalin Test (Pain)

Fabricated in house Used to assess chronic pain
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Grip Strength Meter

Columbus InstrumentsUsed to assess grip strength
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Hargreaves Method to Assess Allodinia

IITCUsed to assess thermal sensitivity and efficacy of analgesics to decease pain sensitivity
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Homecage Monitoring

Fabricated in house Used for long term monitoring of homecage activity of mice. Can provide longitudinal data regarding (eating, resting, grooming, drinking, walking, climbing, rearing, and micromovements). Will be used as a proxy for other more acute tests.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Homecage Wheel Running

Lafayette InstrumentsUsed to assess general levels of locomotor activity and as a proxy to measure changes in circadian rhythms.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Hot Plate Analgesia Meter

BasilleUsed to assess thermal sensitivity.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Light /Dark Box

Fabricated in house Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Marble Burying

Fabricated in house Used to assess anxiety-like behavior and OCD-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Maternal Deprivation

Fabricated in house Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Maternal Separation

Fabricated in house Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Morris Water Maze

Fabricated in house Used to assess spatial learning and memory
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Non-invasive Blood Pressure Monitoring

Columbus InstrumentsTail cuff and apparatus for repeated measurement of blood pressure in mice.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Novel Object Identity

Fabricated in house Used to assess working memory
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Novel Object Location

Fabricated in house Used to assess spatial learning and memory
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Novelty Induced Hypophagia

Fabricated in house Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Novelty Suppressed Feeding

Fabricated in house Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Olfactory Cross-habituation

Fabricated in house Used to assess olfactory acuity.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Olfactory Perceptual Learning

Fabricated in house Used to assess ability to learn to discriminate closely related odor pairs.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Predator Odor Stress

Fabricated in house Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Resident Intruder Aggression

Fabricated in house Used to assess propensity for aggressive behavior.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Restraint Stress

Fabricated in house Used to assess hippocampal atrophy and increased anxiety and depressive-like behavior.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Righting Reflex

Fabricated in house Used to assess coordination and ability to right from a prone position.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Shock Threshold

Fabricated in house Used to assess changes in pain sensitivity
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Single Lane Rotarod

Med AssociatesUsed to assess motor pattern learning and coordination.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Social Defeat Stress

Fabricated in house Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Social Disruption Stress

Fabricated in house Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Social Odor Discrimination

Fabricated in house Used to assess ability to detect and discriminate between odorants of conspecifics.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Sucrose Preference

Fabricated in house Used to asses depressive-like behavior (anhedonia).
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Tail Suspension

Fabricated in house Method to assess depressive-like behavior
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Visual Cliff

Fabricated in house Used to assess depth perception and avoidance learning during visual development.
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - von Frey Filaments

BiosebUsed to assess tactile sensitivity
Rodent Behavioral Phenotyping Facility
Brown University
Behavioral Phenotyping - Wire-hang

Fabricated in house Used to assess animals strength and endurance.
RWU Lab Spaces
Roger Williams University
Fluorescence Activated Cell Sorter (FACS)

Contact: Marcie Marston

Millipore Guava easyCyte Flow CytometerFlow Cytometer
RWU Lab Spaces
Roger Williams University
Gas Chromatograph - Mass Spectrometer (GC - MS)

Contact: Nancy Breen

Agilent 5890 Gas Chromatograph - Mass Spectrometer (GC - MS) wth Mass Selective Detetor (MSD)GC MS for teaching and research
RWU Lab Spaces
Roger Williams University
High Performance Liquid Chromatography (HPLC)

Contact: Nancy Breen

Waters 2695 High Performance Liquid Chromatograph-MS / ZQ Micromass Mass SpectrometerLC - MS for teaching and research
RWU Lab Spaces
Roger Williams University
Gas Chromatograph

Contact: Nancy Breen

Agilent 7890 Gas Chromatography with DB-23 columnGC for fatty acid analysis
Structural Biology Facility
Brown University
Nuclear Magnetic Resonance (NMR) Spectrometer

Bruker 500 Avance II, with TCI cryoprobeAn NMR spectrometer optimized for studying proteins in solution. This spectrometer is most useful for tracking binding interactions, measuring dynamic properties of proteins, and assigning protein resonances. Capable of using 5 mm and 3 mm tubes. Also suitable for proton NMR of small molecules and natural products.
Structural Biology Facility
Brown University
Nuclear Magnetic Resonance (NMR) Spectrometer

Bruker 850 MHz Avance III HD, with TCI cryoprobeAn NMR spectrometer optimized for studying proteins in solution. This spectrometer is ideal for determining protein structures and measuring protein dynamics. Its extreme sensitivity allows studies on otherwise intractable samples. Capable of using 5 mm, 3 mm, and shaped NMR tubes. Also suitable for proton NMR of small molecules and natural products
Structural Biology Facility
Brown University
X-ray Diffraction System

Rigaku ACTOR robot and Saturn 944 HG CCD
Structural Biology Facility
Brown University
X-ray Scattering System

Rigaku BioSAXS 1000 with Pilatus 100K detectorAn instrument useful for collecting small- and wide- angle X-ray scattering data for proteins in aqueous solution. This instrument is useful for assessing molecular size and shape. Temperature controller available.
Tissue Banking Core
Lifespan-Rhode Island Hospital
Bioinformatics Analysis - Database

Software: Database developed in Filemaker ProDatabase and tissue inventory management on a Dell computer workstation
Tissue Banking Core
Lifespan-Rhode Island Hospital
Biospecimen Banking - Biosafety Cabinet

Dissecting hoodHood dedicated to sterile tissue cutting with biohazard protection.
Tissue Banking Core
Lifespan-Rhode Island Hospital
Biospecimen Banking - Freezer System

Forma 195878 LN2 backup for bank freezersSystems inject liquid LN2 into cabinet when cabinet temperature warms to preset level, adjustable in 1 C increments to -150 C.
Tissue Banking Core
Lifespan-Rhode Island Hospital
Biospecimen Banking - Freezing Bath

Low temp isopentane bathBath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.
Tissue Banking Core
Lifespan-Rhode Island Hospital
Histology/Tissue Processing - Freezing Bath

Low temp isopentane bathBath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.
X-ray Reconstruction of Moving Morphology Facility (XROMM)
Brown University
Computed Tomography (CT) Scanner

Animage Fidex VeterinaryVeterinary CT Scanner designed for animals in the size range from rats to dogs. In vivo scanning of anesthetized animals is possible.
X-ray Reconstruction of Moving Morphology Facility (XROMM)
Brown University
Videoradiography Room

Custom made biplanar3D x-ray motion analysis methods that combine skeletal movement data from in vivo x-ray videos with skeletal morphology from 3D bone scans (e.g. computed tomography (CT) or laser scans).
X-ray Reconstruction of Moving Morphology Facility (XROMM)
Brown University
X-ray Fluoroscopes

Radiological Imaging Mobile C-Arm X-ray Two retrofitted with 30-cm image intensifiers and high-speed video cameras for measuring accurate 3D skeletal kinematics of small to medium-sized animals.