Instrument/Service

Facility	Instrument/Services	Manufacturer/Description	Functions
3D Facility for Biomedical Sciences: Animation, Visualization and Printing	3D Printer	Z650 3D System/Z-corp	Produces realistic color (Powder Based) models without paint to better evaluate the look, feel, and style of product designs. Five print heads provide the widest range of accurate colors, including true black and improved color consistency from part to part. 3D print text labels or images can be directly applied onto printed models.
Benedum Stable Isotope Facility	Mass Spectrometer, Isotope Ratio	ThermoFisher (Finnigan) MAT 252 dual inlet Isotope Ratio Mass Spectrometer with automated sample reaction device for up to 48 samples and with Kiel III Carbonate interface.	Instrument primarily dedicated to the measurement of the stable isotopes of carbon and oxygen on inorganic carbonates. The facility accommodates projects both internal and external to Brown including analysis of terrestrial and marine material. The vast majority of samples analyzed are funded through external grants but I also facilitate a significant number of small unfunded, exploratory, analyses to help construct proof-of-concept data sets in preparation for proposals.
Bioinformatics Core	Bioinformatics Analysis Contact: Christopher Hemme	Service	We provide bioinformatics consultation and services to the Rhode Island INBRE community and to the general scientific community of Rhode Island. Our bioinformatics services include standard sequence analysis pipelines as well as 3D vidualization and printing of macromolecules in conjunction with the 3D Visualization Laboratory at URI. We also provide bioinformatics training both individually and in structured workshops.
Biostatistical Consulting and Research Design Services	Biostatistical Consulting and Research Design Services Contact: Heather Fournier	Service	The Clinical Research Design, Epidemiology and Biostatistics Core provides a central location for Rhode Island investigators seeking quantitative and qualitative research design and analysis support through Advance-CTR. The Biostatistics Core links investigators with multidisciplinary faculty members and experts in various methodological techniques including biostatistics, epidemiology, qualitative data techniques and measurement and evaluation in health-related research.
Biostatistics Core at Rhode Island Hospital	Biostatistics Consultation Contact: Jason Machan, PhD	Service	The Biostatistics Core at Rhode Island Hospital offers centralized biostatistics consultation services to Clinical Research Center investigators, providing or steering investigators to a broad array of resources during all phases of research. During planning, the core can provide high quality trial design, including final sculpting of specific aims and hypotheses, measure selection, power analysis, data analysis planning, and grant/proposal preparation. At the beginning of a trial, the core can assist in construction of REDCap data collection tools, databases, and data management protocols, and provide help with special technology needs, such as purchasing non-standard equipment. Throughout the trial, the core can provide decision support, assessing the impact of potential design additions or changes on final statistical inference. It can serve on or help find individuals to serve on the trial’s data and safety monitoring board (DSMB). At the conclusion of the trial, the core can assist with implementation of the data analysis plan, either by providing access to contemporary statistical analysis software and coaching, or by conducting analyses for or with investigators. During reporting/publication preparation, the core can assist in write-up, data visualization, and integration of interpretations in the broader context of the project, and help address comments from peer reviewers.
Brown University Herbarium	Herbarium	Dried and pressed plant specimens mounted on sheets of archival paper. Plant data.	The collection includes around 100,000 plant specimens and is an important depository of Rhode Island and New England collections. It is also rich in western and southern North American plants and includes special sets of historically valuable specimens from 19th and early 20th century western US expeditions. Among other important collections, the herbarium also includes a full set of Charles Wright's Cuban plants (1856-1867) and a unique and classic collection of Carex
Bryant Unistructure Science Spaces	Gas Chromatograph - Mass Spectrometer (GC - MS) Contact: Julia Crowley-Parmentier	Agilent Technologies 7890A GC and 5975C MSD	Analyze for volatile organics; pyrolysis; MSD and FID
Bryant Unistructure Science Spaces	Sample Concentrator, Purge & Trap Contact: Julia Crowley-Parmentier	Teledyne Tekmar velocity XPT sample concentrator and AQUATek 70 vial autosampler	analyze for highly volatile organics; accessory for the GC-MS
Bryant Unistructure Science Spaces	High Performance Liquid Chromatography (HPLC) Contact: Julia Crowley-Parmentier	Shumatzu	Analyze for non-volatile organics
Bryant Unistructure Science Spaces	Spectrometer Contact: Julia Crowley-Parmentier	Agilent Technologies 7700 series Inductive Coupling Plasma Mass Spectrometer( ICP-MS) with ASX-500 series autosampler	Analyze for trace elements
Bryant Unistructure Science Spaces	Solvent Extractor Contact: Julia Crowley-Parmentier	Dionex ASE 350 Accelerated Solvent Extractor (ASE)	Accelerated extractions
Bryant Unistructure Science Spaces	Concentrator Worstation Contact: Julia Crowley-Parmentier	Caliper LifeSciences Turbo Vap LV Concentration Workstation	Concentrator
Bryant Unistructure Science Spaces	Freeze Dry System Contact: Julia Crowley-Parmentier	Labconco FreeZone 4.5	Freeze dryer
Bryant Unistructure Science Spaces	Spectrophotometer Contact: Julia Crowley-Parmentier	Shimadzu UV 2600	UV/Vis spectrophotometer for quantifying concentrations
Bryant Unistructure Science Spaces	Spectrophotometer	Thermo Scientific AquaMate Plus	UV/Vis spectrophotometer for quantifying concentrations
Bryant Unistructure Science Spaces	Microscope - Electron Contact: Julia Crowley-Parmentier	JEOL JSM 6010LA Scanning Electron Microscope (SEM)	Scanning electron microscope with EDS
Bryant Unistructure Science Spaces	Critical Point Dryer Contact: Julia Crowley-Parmentier	Tousimis Sandri-PVT-3D Critical Point Dryer (CPD)	Maintain structural integrity for soft tissue use of the SEM
Bryant Unistructure Science Spaces	Sputter Coater System Contact: Julia Crowley-Parmentier	Denton Vacuum Desk V gold sputter coater and carbon coater	Coat non-conducting samples with gold or carbon for use on the SEM
Bryant Unistructure Science Spaces	Microscope Contact: Julia Crowley-Parmentier	Zeiss A1 AXIO Polarized Light Microscope and Q imaging RETIGA 400R Imager	Recordable polarized light imaging
Bryant Unistructure Science Spaces	Microscope Contact: Julia Crowley-Parmentier	Zeiss Axiovert 40CFL Inverted Microscope	Recordable inverted microscopy
Bryant Unistructure Science Spaces	Microscope Contact: Julia Crowley-Parmentier	Zeiss Primo Star with AxioCam	Recordable imaging
Bryant Unistructure Science Spaces	Anaerobic Chamber Contact: Julia Crowley-Parmentier	Microbiology International Whitley DG250 Anaerobic Workstation	Simulate anoxic environments for anaerobic work
Bryant Unistructure Science Spaces	Anaerobic Chamber Contact: Julia Crowley-Parmentier	MBRAUN Labstar Anaerobic Glovebox Workstation	simulate anoxic environments for anaerobic work
Bryant Unistructure Science Spaces	PCR Thermal Cycler Contact: Julia Crowley-Parmentier	Bio-Rad PCR Thermocycler C1000 Touch; Fraction Collector model 2110	DNA amplifier
Bryant Unistructure Science Spaces	Biological Safety Cabinet Contact: Julia Crowley-Parmentier	LABGARD ES class II, type A2 Biological Safety Cabinet	Maintain sterility and contain infectious work
Bryant Unistructure Science Spaces	Freezer Contact: Julia Crowley-Parmentier	Thermo Scientific Isotemp Basic U86-13A41 minus 70 degree freezer	Long term storage of biological specimens
CCRI Biology Labs	Autoclave	Consolidated Stills & Sterilizers 24D36	Sterilization. Chamber size is 24inch x36inch, Volume 9.4 cu. Ft
CCRI Biology Labs	Balance - Analytical	Orion Analytical Balance	Weight determination with capacity of 60g.
CCRI Biology Labs	Balance - Top Loading	EK-I Compact Balance	Weight determination (2 units)
CCRI Biology Labs	Incubator	Fisher Scientific Isotemp Digital & Analog Dry Bath Incubator	Provide controlled dry heat environment for clinical & general chemistry applications
CCRI Biology Labs	Electrophoresis System	Bio-Rad Mini-Protean Tetra Cell, Vertical protein electrophoresis gel boxes	Running Protein or DNA polyacrylamide gels
CCRI Biology Labs	Microscope	Lieder MI-500 Series Compound Inverted Microscope	Tissue Culture
CCRI Biology Labs	pH Meter	Thermo Scientific Orion 2-Star Bench Top pH Meter	General purpose measurements
CCRI Biology Labs	Blotting System, Semi-Dry	Shelton Scientific Semi-Dry Blotting System	Transfer of protein, RNA & DNA gels to a solid membrane support for visualization, 24cmx30cm.
CCRI Biology Labs	Spectrophotometer	Thermo Scientific Genesis 20 Visible Spectrophotometer	UV spectrophotometer for quantifying concentrations
CCRI Biology Labs	Transilluminator	FOTODYNE Foto Phoresis UV Transilluminator	Imaging-protein gel analysis, GFP Analysis
CCRI Biology Labs	Incubator - Shaker	Lab Companion IS-971 Floor Model Incubator Shaker	Growing of bacteria, 250 L chamber
CCRI Biology Labs	Biological Safety Cabinet	NuAire Class II Type A2	Maintain sterility and contain infectious work
Cell Analysis and Sorting Core	Flow Cytometer Contact: Alan Rothman	Miltenyi MACSQuant-10 Analytical Flow Cytometer	Analytical flow cytometry- 3 lasers, 10 parameters (8 colors, FSC, SSC)
Cell Analysis and Sorting Core	Imaging System - Plate Reader Contact: Alan Rothman	Biotek Cytation 3	Imaging plate reader; 5 colors (brightfield, GFP, RFP, DAPI, Cy5); 10x, 20x, 60x objectives
Cell Analysis and Sorting Core	Microscope Contact: Alan Rothman	Life Technologies Evos fl, Fluorescence Microscope	Fluorescence microscope; 4 colors (GFP, RFP, DAPI, Cy5); 10x, 40x, 100x objectives
Cell Analysis and Sorting Core	Cell Sorter - Magnetic Contact: Alan Rothman	Miltenyi AutoMACS	Automated cell sorter for cell suspensions labeled with magnetic beads.
Cell Analysis and Sorting Core	Microplate Reader Contact: Alan Rothman	Perkin-Elmer Envision	Multimodal plate reader- absorbance, luminescence, fluorescence, time-resolved fluorescence, AlphaScreen
Cell Analysis and Sorting Core	Flow Cytometer Contact: Alan Rothman	Analytical flow cytometric analysis; 4 lasers (blue (2), violet (4), red (3) and yellow green (5)) which allows for analysis of up to 14 different fluors (# listed in parentheses for each laser)	BD LSRII
Cell Isolation & Organ Function Core	Analyzer - Cell Metabolism	Seahorse Biosciences - XF Extracellular Flux Analyzer	XF instruments analyze mitochondrial respiration and glycolysis in live cells, generating data in just minutes. XF Technology uses solid-state sensors to simultaneously measure both oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in every well. All platforms support injection of up to 4 unique compounds per well.
Cell Isolation & Organ Function Core	Electrical Cell Impedance Sensing (ECIS) equipment	Applied BioPhysics, Model 100	Measures cell impedance using altering currents across cell monolayers and measuring the change in electrical potential. Impedance is calculated using Ohm's law.
Cell Isolation & Organ Function Core	Electrical Cell Impedance Sensing (ECIS) equipment	Applied BioPhysics, Model ECIS Z Theta	Measures cell impedance using altering currents across cell monolayers and measuring the change in electrical potential. Impedance is calculated using Ohm's law.
Cell Isolation & Organ Function Core	Imaging System - Slide Scanner	Aperio ScanScope CS Digital Slide Scanner CS	Brightfield 5 slide scanner with two workstations with Aperio brightfield imaging analysis software.
Cell Isolation & Organ Function Core	Imaging System - Slide Scanner	Aperio Scan Scope FL Fluorescent Digital Slide Scanner	5 slide scanner with Indica Labs fluorescence imaging analysis software.
Cell Isolation & Organ Function Core	Flow Cytometer	Miltenyi MACSQuant Analyzer 7	The MACSQuant Analyzer is a powerful benchtop flow cytometer for highly sensitive, multiparameter cell analysis. MACSQuant Analyzers offer fully automated instrument setup via pre-set calibration and compensation programs. Automated startup, shutdown, and cleaning cycles make for hassle-free instrument housekeeping. The MACSQuantify™ Software provides a powerful and easy-to-use user interface for instrument control, data acquisition, and fully automated analysis.
Cell Isolation & Organ Function Core	Evaporator	Buchi RotaVapor R215 Evaporator	Rotary evaporator for removing solvents.
Cell Isolation & Organ Function Core	Ventilator - Mechanical	SCIREQ Flexivent	Contains a computer-controlled precision piston pump that can intersperse mechanical ventilation with a variety of volume and pressure controlled maneuvers to obtain accurate, reproducible measurement of respiratory mechanics for pulmonary research.
Cell Isolation & Organ Function Core	Imaging System - Echocardiograph	VisualSonics, Vevo 2100 Imaging System	A high-frequency, high-resolution digital imaging platform with linear array technology and Color Doppler Mode. The Vevo 2100 Imaging System enables in vivo visualization, assessment, and measurement of anatomical structures and hemodynamic function in longitudinal imaging studies for small animal phenotyping.
Cell Isolation & Organ Function Core	Channel Cycling Metabolic System	For rodent cardiopulmonary exercise Testing	OmniTech ElectronicsModel #80 AP4RAT AccuPacer 4 Channel Rat Treadmill and #75 MS8 8
Center for Computation and Visualization	High Performance Computing Cluster	Various including IBM idataPlex High Performance Computing Cluster	HPC cycles, software development, storage, backups, high speed network hub, visualization, virtual reality, data management, server colocation, scientific support
Centralized Research Core Facility	Analyzer - Live Cell	Roche xCELLigence Real-Time Cell Analysis System	Label free live cell analyzer
Centralized Research Core Facility	Biological Safety Cabinet	NuAire, Laminar Flow Hood	Cell culture facility
Centralized Research Core Facility	Cell Counter	Nexcellom Cellometer Vision Cell Counter	Automated cell counter
Centralized Research Core Facility	Centrifuge	Beckman Avante High Speed Centrifuge	High speed centrifuge
Centralized Research Core Facility	Centrifuge	Thermo MultiFuge Centrifuge table-top	Centrifuge
Centralized Research Core Facility	Centrifuge - Ultra	Beckman Coulter Optima	Ultra centrifuge
Centralized Research Core Facility	Centrifuge - Ultra	Sorvall Micro Ultra Centrifuge	Ultra centrifuge
Centralized Research Core Facility	Evaporator	Buchi RotaVap System	Rotary evaporator
Centralized Research Core Facility	Fluorescence Activated Cell Sorter (FACS)	Becton Dickinson (BD) Biosciences FACS Verse Flow cytometer	FACS
Centralized Research Core Facility	Gel Electrophoresis	Agilent Offgel Fractionator 3100	Liquid phase Isoelectric Focusing (IEF) System
Centralized Research Core Facility	Gel Electrophoresis	Bio-Rad 2D Gel System	Two Dimensional (2D) Gel Electrophoresis
Centralized Research Core Facility	Gel Electrophoresis	Bio-Rad PAGE Electrophoresis System	One Dimensional (1D) Gel Electrophoresis
Centralized Research Core Facility	High Performance Liquid Chromatography - Ultra High (UHPLC)	Hitachi UPLC System	UPLC
Centralized Research Core Facility	Chromatography	GE AKTA Fast Protein Liquid Chromatograph (FPLC)	FPLC
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC)	Hitachi Analytical HPLC	HPLC
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC)	Hitachi Prep-HPLC System	HPLC
Centralized Research Core Facility	Chromatography	Teledyne-ISCO CombiFlash System	Flash Chromatography
Centralized Research Core Facility	Imaging System - Gel Imager	GE Imagescanner II	Gel imager
Centralized Research Core Facility	Imaging System - Gel Imager	GE Typhoon FLA 9000 Multimode Imager	Gel imager
Centralized Research Core Facility	Imaging System - Gel Imager	Li-Cor Odyssey IR Imager	IR gel imager
Centralized Research Core Facility	Liquid Chromatography - Mass Spectrometer (LC - MS)	AB SCIEX TripleTOF 4600 and Shimadzu Prominence UFLC sytem	ESI-TOF MS
Centralized Research Core Facility	Mass Spectrometer	Shimazu Axima MALDI-TOF MS/MS	MALDI MS
Centralized Research Core Facility	Mass Spectrometer	Thermo iCAPQ-a ICP-MS	Elemental Analyzer
Centralized Research Core Facility	Microplate Reader	BMG LabTech Microplate Reader	Fluorescence/UV/VIS
Centralized Research Core Facility	Microplate Reader	Molecular Devices SpectraMax M2	Fluorescence/UV/VIS
Centralized Research Core Facility	Microplate Reader	Promega GlowMax System	Chemiluminescence
Centralized Research Core Facility	Microscope	Nikon Eclipse E600 Upright Microscope	Microscope
Centralized Research Core Facility	Microscope	Nikon TE2000E /C2 Inverted Confocal	Confocal Microscope
Centralized Research Core Facility	PCR Thermal Cycler	Applied Biosystems/Life Technologies ABI Vii7- RT-PCR	RT-PCR
Centralized Research Core Facility	PCR Thermal Cycler	Eppendorf Mastercycler PCR	PCR
Centralized Research Core Facility	Protein Sequencer	Shimadzu PPSQ-31A protein sequencer	N-terminal protein sequencer
Centralized Research Core Facility	Robotic Workstation - Liquid Handler	BioTek Precision XS Sample Processor	Sample processor
Centralized Research Core Facility	Robotic Workstation - RNA/DNA	Fuji Film DNA/RNA Isolation System	DNA/RNA isolation
Centralized Research Core Facility	Scintillation Counter	PerkinElmer Microbeta1450 Scintillation Counter	Scintillation counter
Centralized Research Core Facility	Scintillation Counter	PerkinElmer Wizard 1470 Gamma Counter	Gamma counter
Centralized Research Core Facility	Spectrometer	PerkinElmer Luminescence Spectrometer LS55	Fluorescence
Centralized Research Core Facility	Spectrometer	Jasco J-1100 Circular Dichroism (CD) Spectropolarimete	CD
Centralized Research Core Facility	Spectrometer	Thermo Nicolet 380 Fourier Transformed Infrared Spectrometer (FT-IR)	FT-IR
Centralized Research Core Facility	Spectrophotometer	Beckman UV/VIS DU800	UV/VIS
Centralized Research Core Facility	Chromatography	Metrohm Ion Chromatography 940 Vario	Ion Chromatography
Centralized Research Core Facility	Spectrophotometer	Thermo Scientific NanoDrop	UV/VIS
Centralized Research Core Facility	Transfection Platform	Lonza Nucleofactor System	High-throughput transfection
Centralized Research Core Facility	Water Purification System - Deionized (DI)	Millipore Milli-Q Water System	DI water System
Centralized Research Core Facility	Western Blotting System	Bio-Rad Turbo Trans Blot system	Western Blotting
Centralized Research Core Facility	Western Blotting System	Life Technologies BenchPro Western System	Western Blotting processor
Centralized Research Core Facility	Western Blotting System	Protein Simple Simon Western	Liquid phase Western Blotting
Centralized Research Core Facility	Synthesizer, DNA/RNA	MerMade-4 Oligonucleotide synthesizer	DNA/RNA Synthesizer
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC)	Shimadzu Nexera-i HPLC system	HPLC
Centralized Research Core Facility	Microscope	EVOS FL Auto Cell Imaging System	Microscope
Centralized Research Core Facility	Spectrometer	Jasco Digital Polarimeter P2000	Polarimeter
Core Research Laboratories	Cryostat Contact: Paul Monfils	Reichert-Jung Cryocut 1800	Frozen tissue sectioning (used with Superfrost/Plus microscope slides (approximately 4-10 microns).
Core Research Laboratories	Fluorescence Activated Cell Sorter (FACS) Contact: Paul Monfils	Becton Dickinson (BD) Biosciences FACS Vantage Flow Cytometer	High-speed cell sorter. Two lasers analyze cells on 8 parameters. Side/ forward light scatter. 6 different fluorescent color detection. Simultaneously sort up to four populations of cells. Sort 1+ cell type(s) into 6, 24, and 96 well tissue culture plates.
Core Research Laboratories	Fluorescence Activated Cell Sorter (FACS) Contact: Paul Monfils	Becton Dickinson (BD) Biosciences FACSort Flow Cytometer	Analytical flow cytometer. Two lasers analyze cells on 6 parameters. Side/ forward light scatter. 4 different fluorescent color detection.
Core Research Laboratories	Histology/Tissue Processing - Biosafety Cabinet Contact: Paul Monfils	Laminar Flow Hood	Filter capable of removing 99.97% of particles greater than 0.3 microns.
Core Research Laboratories	Histology/Tissue Processing - Knife Sharpener Contact: Paul Monfils	Hecker Instruments, Inc. Knife Sharpener	Used to sharpen microtome/cryostat knife.
Core Research Laboratories	Histology/Tissue Processing - Microwave Oven Contact: Paul Monfils	Sharp Microwave Oven	Tissue microwave fixation.
Core Research Laboratories	Histology/Tissue Processing - Oven Contact: Paul Monfils	Fisher Scientific Oven	Used to melt paraffin from paraffin- embedded sections.
Core Research Laboratories	Histology/Tissue Processing - Paraffin Embedding Workstation Contact: Paul Monfils	Miles Scientific Tissue-Tek III	Paraffin embedding sample station (tissue, bone, cell pellet, etc.).
Core Research Laboratories	Histology/Tissue Processing - Tissue Processor Contact: Paul Monfils	Miles Scientific Tissue-Tek-VIP Tissue Processor	Automated sample processing (tissue, bone, cell pellet, etc.) for paraffin embedding purposes.
Core Research Laboratories	Hybridization Oven Contact: Carol Ayala	Panomics-Luminex Hybridization oven	Horizontal air flow oven for optimal temperature uniformity.
Core Research Laboratories	Imaging System - Camera Contact: Ginny Hovnesian	Diagnostics SPOT 110-2 Digital Camera	Digital Imaging of samples.
Core Research Laboratories	Imaging System - Camera Contact: Ginny Hovnesian	Olympus SPOT IDEA 3.0 MP Digital Camera	Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Core Research Laboratories	Imaging System - Camera Contact: Ginny Hovnesian	SPOT RT3 Slider -43C F-MT Digital Camera	Attached to Nikon TE-800. Digital Imaging of samples. Ideal for brightfield color imaging, fluorescence microscopy, FISH, GFP imaging, immuno- fluorescence, 3D convolution. CCD cooled to -43.3. 1.92 MP. 1-16x. 14-bit x 20MHz capture, 40MHz live mode, interline progressive scan, FireWire interface.
Core Research Laboratories	Imaging System - Dark Room Contact: Paul Monfils	Dark Room Related equipment eg., automatic processors, dryers, et al	Sample photo development.
Core Research Laboratories	Imaging System - Photo Enlarger Contact: Carol Ayala	Durst Laborator 1200 Photographic Enlarger	Sample digital imaging using high performance enlarger.
Core Research Laboratories	Microscope Contact: Carol Ayala	Bausch Lomb Stereomicrosopes	Visualization with incident light illumination.
Core Research Laboratories	Microscope Contact: Ginny Hovnesian	NIKON E-800 Fluorescent /Brightfield Microscope	Fluorescence/Brightfield- micro- scope slides only. CFI60 optical system. 0.5x magnification with 50mm field of view. Can be coupled with 2x projection lens to permit macrophotography at 1:1 magnification. Tube lens focal length of 200mm. 10 types of condensers available.
Core Research Laboratories	Microscope Contact: Ginny Hovnesian	Nikon TE 200 Inverted Fluorescent/Brightfield Microscope	Fluorescence/Brightfield Microscope- petri dish/microscope slides on cell/slice culture etc. Phase contrast and fluorescence.
Core Research Laboratories	Microscope Contact: Paul Monfils	Olympus BHTU Upright Light Microscope	Light Microscope for viewing tissue or cell samples on microscope slides. 45mm parfocal distance system, corrected for a mechanical tube length of 160mm. Two types of standard objectives, D Achromats and D Plan Achromats, magnifications of 4x, 10x, 20x, 40x, 100x. FN20. Equipped for epifluorescence microscopy.
Core Research Laboratories	Microscope Contact: Paul Monfils	Olympus IMT-2 Inverted Light Microscope	Light Microscope use to view cell/slice/tissue culture samples (microscope slide or petri dish). Inverted research microscope equipped with phase contrast optics.
Core Research Laboratories	Microscope Contact: Carol Ayala	Zeiss S-16 Light Microscope	Light Microscope used to view 1 micron sectioned resin-embedded samples.
Core Research Laboratories	Microscope	NIKON C1Si Spectral Live Cell Confocal Inverted Microscope System	For use with microscope slide. Four diode lasers that excite at 402, 488, 561, & 638 and has spectral capabilities. Suitable for tissue, live cell imaging, time events, FRAP, FRET, deconvolutions, colocalization analysis and 3D reconstructions.
Core Research Laboratories	Microscope - Electron Contact: Carol Ayala	Morgagni 268 Fully Digitized Transmission Electron Microscope (TEM)	Ultrastructural analysis (tissue, cells) on stained ultra-thin sections contrasted with uranyl acetate and lead citrate. Examined with Morgagni 268 transmission electron microscope that is fully digitized, high performance, 100 kv, and images collected with an AMT Advantage 542 CCD camera system.
Core Research Laboratories	Microtome Contact: Carol Ayala	Bausch Lomb Ultramicrotome	Sectioning resin-embedded tissue; micron-nm thickness.
Core Research Laboratories	Microtome Contact: Paul Monfils	Reichert-Jung Microtome	Paraffin embedded tissue sectioning (approximately 2-20 microns).
Core Research Laboratories	Vibratome Contact: Carol Ayala	Bausch Lomb Vibratomes	Sectioning agarose-embedded tissue.
Core Research Laboratories	Vibratome Contact: Paul Monfils	Vibratome 3000 Sectioning System	Fresh tissue sectioning. Thickness: 3- 20 microns.
Electron Microprobe Facility	Analyzer - Electron Microprobe Contact: Stephen Parman	Cameca SX100 Electron Microprobe Analyzer	The Cameca SX-100 electron microprobe is equipped with 5 wavelength dispersive spectrometers (WDS) and a Rontec energy dispersive spectrometer (EDS).The WDS spectrometers each contain two or four diffracting crystals and presently include LTAP, TAP (2), LPET (2), PET, LLIF (2), LIF, LPCO, PC1 and PC2. The last three crystals are used to measure the light elements (boron to sodium). The absolute detection limits for the instrument are approximately 50-200 ppm, depending on the element. The EDS spectrometer is capable of detecting all elements above sodium (Na). X-ray element maps can easily be acquired on the microprobe. Using 512x512 pixel maps, up to nine element maps (5 elements on WDS, 4 with EDS), plus a backscattered electron (BSE) image, can be obtained simultaneously. Maximum resolution on any one map is one micron per pixel. Utilizing the coordinate system, maps of entire thin sections can be generated.
Environmental Chemistry Facility	Analyzer - Discrete Analyzer	Westco Smartchem 200	Used to determine Nitrate/Nitrite, Phosphate, Ammonia, Silicate, and other nutrient concentrations in water samples and soil extracts.
Environmental Chemistry Facility	Analyzer - Elemental Analyzer	CE Elantech, Carbon-Nitrogen NC2100	Analysis of carbon, nitrogen, and sulfur concentration of solid samples
Environmental Chemistry Facility	Analyzer - Inorganic Carbon Analyzer	UIC, INC Inorganic Carbon Analyzer	Measures total inorganic carbon by automated acidification and coulometric detection in a wide variety of sample matrices. Solid samples ranging from low ppm to 100% inorganic carbon can be analyzed with this system.
Environmental Chemistry Facility	Analyzer - Mercury Analyzer	Milestone DMA-80 Direct Mercury Analyzer	Determines mercury content of solid and liquid samples.
Environmental Chemistry Facility	Analyzer - Water Isotope	Picarro L1102-I	Measures delta deuterium/hydrogen (D/H) ratio and delta 18O/16O in liquid water
Environmental Chemistry Facility	Freeze Dry System	Labconco FreeZone 6 Liter	For removing water and other solvents from frozen samples by sublimation.
Environmental Chemistry Facility	Liquid Chromatography System	Dionex DX500	Ion chromatography analysis of ions in marine and freshwater samples
Environmental Chemistry Facility	Microwave Digestion System	Milestone Ultrawave	Used to digest solid samples (soils, sediments, rocks, plants, tissues), for elemental analysis.
Environmental Chemistry Facility	Spectrometer - Atomic Absorption Spectrometer-Graphite Furnace (GFAAS)	Perkin Elmer AAnalyst 600 Graphite Furnace	This spectrometer is useful for measuring trace levels of metals in water and soil.
Environmental Chemistry Facility	Spectrometer - Atomic Emission Spectrometer (AES)	Jobin Yvon JY2000 Ultrace Inductively coupled plasma atomic emission spectrometer (ICP-AES)	Analysis of most elements with atomic weights above 10.
Environmental Chemistry Facility	X-Ray Fluorescence - Handheld	Innov-X Systems Alpha 4000 Handheld	Non-destructive elemental analysis on a variety sample types for concentrations of some metalsranging from about 20 ppm to 10%.
Environmental Chemistry Facility	X-Ray Fluorescence - Handheld	Olympus Delta Professional Handheld	Non-destructive elemental analysis on a variety sample types for concentrations of elements greater than 10 ppm.
Flow Cytometry and Sorting Facility	Fluorescence Activated Cell Sorter (FACS)	Becton Dickinson (BD) Biosciences FACS Aria III	Cell counting, sorting, biomarker detection. The FACSAria has four air-cooled lasers at 488nm, 561nm, 633nm, and 407nm allowing multicolor analysis of up to 19 parameters. It can sort 1 to 4 populations simultaneously and is equipped with an Automated Cell Deposition Unit, an Aerosol Management System and a refrigeration system. It can accept various sample input tubes including 1 mL microtubes, 12 x 75-mm test tubes, and 15 mL tubes into the sample and collection chambers.
Flow Cytometry Core	Cell Sorter	Beckman Coulter / Modular Flow (MoFlo) high-speed cell sorter	Rapidly sorts with a very >99% purity at sorting speeds of up to 70,000 events per second. Equipped with four lasers with the capability of detecting up to eight colors simultaneously. Capable of simultaneously “bulk” sorting one to four populations into test tubes of varying sizes. Equipped with a CyClone Automated Cell Deposition Unit which allows for rapid and accurate cell deposition into various multi-well plate formats (single cell to multiple cells per well).
Flow Cytometry Core	Flow Cytometer	Beckman Coulter / CyAn ADP flow cytometer	Configured with three lasers (blue 488nm, red 642nm and violet 405nm), and has the capability to simultaneously detect up to 9 different fluorophores.
Flow Cytometry Core	Flow Cytometer	Becton Dickinson / LSRII flow cytometer	Configured with three lasers (blue, red and UV), and has the capability to simultaneously detect up to 8 different fluorophores.
Flow Cytometry Core	Separator	Miltenyi / AutoMACS Pro Separator	Allows for the enrichment of specific cellular populations prior to downstream applications, such as cell sorting. This procedure efficiently “de-bulks” large samples which would otherwise require a significantly longer time for isolation by FACS alone.
Flow Cytometry Core	Summit and FACSDiva Flow Analysis Workstation	Dell XDP desktop computer	This separate analysis workstation enables data analysis to occur concurrent with sample acquisition by other investigators using either of the flow cytometers.
Genomics & Sequencing Center	Bioanalyzer Contact: Janet A. Atoyan, Genomics Technician	Agilent Bioanalyzer 2100	Provides fast and automated separation, sizing and quantification of DNA, RNA and proteins by miniaturized Lab-on-a-Chip electrophoresis
Genomics & Sequencing Center	Bioinformatics Analysis - DNA Sequence and Protein Analysis Contact: Janet A. Atoyan, Genomics Technician	Software: DNAStar Lasergene Core Suite	Comprehensive suite of software modules for DNA, RNA, and protein sequence analysis
Genomics & Sequencing Center	Bioinformatics Analysis - Next Generation DNA Sequence Assembly Contact: Janet A. Atoyan, Genomics Technician	Software: CLCbio Genomics Workbench	Software for analyzing, comparing, and visualizing Next Generation Sequencing data
Genomics & Sequencing Center	Centrifuge Contact: Janet A. Atoyan, Genomics Technician	Beckman Coulter Allegra 25R Refrigerated Centrifuge	Centrifuge for pelleting cells, tissues and macromolecules
Genomics & Sequencing Center	Centrifuge Contact: Janet A. Atoyan, Genomics Technician	Thermo Savant DNA110 SpeedVac Vacuum Centrifuge	Centrifugal concentration system for drying low-volume ethanol or isopropanol precipitates of DNA and RNA
Genomics & Sequencing Center	Cryostat Contact: Janet A. Atoyan, Genomics Technician	Vibratome 5000 Advanced Cryostat	Performs histological sectioning of unfixed frozen cells and tissues.
Genomics & Sequencing Center	Disrupter Contact: Janet A. Atoyan, Genomics Technician	Covaris S220 High Performance Ultrasonicator	Automated acoustic disruption and homogenization of cells and tissue samples using focused ultrasonic energy at 500 KHz. Performs DNA Shearing
Genomics & Sequencing Center	Disrupter Contact: Janet A. Atoyan, Genomics Technician	QIAGEN TissueLyser	Provides rapid and efficient disruption of cells and tissues
Genomics & Sequencing Center	DNA Sequencer Contact: Janet A. Atoyan, Genomics Technician	Applied Biosystems 3130xl & 3500xl Genetic Analyzers	DNA Sanger Sequencing & Fragment Analysis: Fluorescence-based instruments utilizing capillary electrophoresis for DNA sequencing and fragment analysis
Genomics & Sequencing Center	DNA Sequencer Contact: Janet A. Atoyan, Genomics Technician	Illumina MiSeq DNA NextGen Sequencing	Performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting
Genomics & Sequencing Center	Electrophoresis System Contact: Janet A. Atoyan, Genomics Technician	Sage Science BluePippin DNA Electrophoresis System	A preparative electrophoresis platform that separates and extracts DNA fragments using pre-cast gel cassettes
Genomics & Sequencing Center	Fluorometer Contact: Janet A. Atoyan, Genomics Technician	Invitrogen Qubit	Fluorometer that uses fluorescent dyes bound to specific molecules to quantify DNA, RNA and proteins
Genomics & Sequencing Center	Imaging System - Camera Contact: Janet A. Atoyan, Genomics Technician	Zeiss AxioCam HRc high-resolution imaging systems	A digital Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module. For use on the AxioImager upright light microscope
Genomics & Sequencing Center	Library Preparation System Contact: Janet A. Atoyan, Genomics Technician	IntegenX Apollo 324 System NextGen Sequencing (NGS) Library Preparation System	Automated liquid handling instrument dedicated to the preparation of sample libraries for Next Generation Sequencing
Genomics & Sequencing Center	Microarray Platform Contact: Janet A. Atoyan, Genomics Technician	BioLog OmniLog Phenotype Microarray System Plate Incubator/Reader	Uses Phenotype Microarrays in microtiter plates to test for unique phenotypes or cell functions
Genomics & Sequencing Center	Microscope Contact: Janet A. Atoyan, Genomics Technician	Zeiss AxioImager M2 Upright Light Microscope	For use with the AxioImager upright light microscope equipped for digital image acquisition with a Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module
Genomics & Sequencing Center	PCR Thermal Cycler Contact: Janet A. Atoyan, Genomics Technician	Agilent Mx3005P and Roche LC480 qPCR Systems	3 Quantitative PCR (qPCR) instruments. Used for highly accurate qualitative and quantitative detection of nucleic acids and gene expression .
Genomics & Sequencing Center	PCR Thermal Cycler Contact: Janet A. Atoyan, Genomics Technician	Eppendorf Mastercycler ep Gradient S and MJ Research PTC-100	(3) Thermal cyclers in 96-well format; peltier elements control the temperature of the block for PCR chemistry
Genomics & Sequencing Center	PCR Workstation Contact: Janet A. Atoyan, Genomics Technician	AirClean Systems 600 PCR Workstation	Combination workstation provides an ISO 5 (FS209E) Class 100 clean air environment and UV light sterilization
Genomics & Sequencing Center	Robotic Workstation - Automated Pipetting Contact: Janet A. Atoyan, Genomics Technician	Eppendorf epMotion 5075 VAC Pipetting Workstation	Automated pipetting workstation enables fast and reproducible liquid handling for a variety of applications
Genomics & Sequencing Center	Robotic Workstation - Sample Preparation Contact: Janet A. Atoyan, Genomics Technician	QIAGEN QIAcube Spin Column Robot	Automated protocols for purification of plasmid DNA, genomic DNA, RNA, viral nucleic acids, and proteins
Genomics & Sequencing Center	Spectrophotometer Contact: Janet A. Atoyan, Genomics Technician	Thermo Scientific NanoDrop 8000	Spectrophotometer that accurately measures up to eight individual 1-2 microliter samples simultaneously
Genomics Facility	Bioanalyzer Contact: Christoph Schorl	Agilent Bioanalyzer 2100	Microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cells
Genomics Facility	Capillary Electrophoresis Contact: Christoph Schorl	Advanced Analytical, Fragment Analyzer	Analyze DNA fragments for Next-Gen Sequencing, genotyping, checking RNA quality and quantity, and working with microsatellite simple sequence repeats (SSRs).
Genomics Facility	Cell Counter Contact: Christoph Schorl	Life Technologies Automated Countess Cell Counter	Measure cell count and viability (live, dead, and total cells) using the standard trypan blue technique.
Genomics Facility	Centrifuge Contact: Christoph Schorl	Sorvall Legend T Benchtop	Low to medium speed centrifugation
Genomics Facility	Centrifuge - Ultra Contact: Christoph Schorl	Beckman Coulter Optima Max	High speed centrifugation with MLA130, TLA110 & TLA100 Rotors
Genomics Facility	Disrupter Contact: Christoph Schorl	Covaris S220 High Performance Ultrasonicator	DNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization
Genomics Facility	Fluorescence Activated Cell Sorter (FACS) Contact: Christoph Schorl	Becton Dickinson (BD) Biosciences FACS Calibur	Flow cytometry cell analysis and cell sorting
Genomics Facility	Hybridization Oven Contact: Christoph Schorl	Agilent G2534A	Microarray hybridization oven
Genomics Facility	Imaging System Contact: Christoph Schorl	LiCor Odyssey Clx Infrared	Western blot analysis, EMSA, protein arrays, In-Cell Western Assays, On-Cell Westerns, in vivo imaging, Coomassie gel documentation, DNA gel documentation, and tissue section analysis.
Genomics Facility	Imaging System Contact: Christoph Schorl	Molecular Dynamics Typhoon 9410	Imaging system for gel sandwiches agarose and polyacrylamide gels membranes, microplates and microarrays.
Genomics Facility	Microarray Platform Contact: Christoph Schorl	Affymetrix Gene Chip Instrument System	A fully integrated platform for Affymetrix microarrays
Genomics Facility	Microarray Scanner Contact: Christoph Schorl	Molecular Devices GenePix Scanner 4000B	Two color microarray scanner
Genomics Facility	Microplate Reader Contact: Christoph Schorl	Molecular Devices Spectra Max M5	Detects UV-Visible Absorbance (Abs), Fluorescence Intensity (FI), Time-Resolved Fluorescence (TRF), Fluorescence Polarization (FP), Glow Luminescence (Lumi)
Genomics Facility	PCR Thermal Cycler Contact: Christoph Schorl	Applied Biosystems 7900 Fast Real Time PCR System	96- and 384-well fast real time, quantitative PCR formats
Genomics Facility	PCR Thermal Cycler Contact: Christoph Schorl	Applied Biosystems viia-7-real-time-system	Medium to high throughput 96- and 384-well fast real time quantitative PCR formats, medium to high throughput
Genomics Facility	PCR Thermal Cycler Contact: Christoph Schorl	Applied Biosystems Viia-7-real-time-system	Medium to high throughput 96- and 384-well fast real time quantitative PCR formats, medium to high throughput
Genomics Facility	Spectrophotometer Contact: Christoph Schorl	Thermo Scientific Nanodrop One	A microvolume spectrophotometer for measuring DNA, RNA, and protein.
Genomics Facility	Technical Assistance - Affmetrix Microarray Contact: Christoph Schorl	Service	Service to provide Affymetrix gene expression array service
Genomics Facility	NGS library quality control Contact: Christoph Schorl	Service	Analysis of library size distribution and qPCR quantification
Genomics Facility	Technical Assistance - Next Generation (NextGen) Sequencing (NGS) Contact: Christoph Schorl	Service	Service to provide Illumina platform based NextGen sequencing
Genomics Facility	Microplate Reader Contact: Christoph Schorl	BioTek Cytation 3 Cell Imaging Multi-Mode Reader	UV-Vis absorbance, Fluorescence intensity, Luminescence, Fluorescence polarization, Time-resolved fluorescence
Good Manufacturing Practice (GMP) Facility (RWMC)	Cell production	Service	Produce gene modified T-cell (capacity > 1011 cells/ batch)
Good Manufacturing Practice (GMP) Facility (RWMC)	BiAb production	Service	Bispecific antibodies production by biochemical conjugation
Good Manufacturing Practice (GMP) Facility (RWMC)	Bio-safety Cabinets
Good Manufacturing Practice (GMP) Facility (RWMC)	Laminar Flow Work Station
Good Manufacturing Practice (GMP) Facility (RWMC)	CO2 Incubators (reach-in)
Good Manufacturing Practice (GMP) Facility (RWMC)	Wave Bioreactors
Good Manufacturing Practice (GMP) Facility (RWMC)	Freezers		Liquid Nitrogen Freezers, -80oC Freezers, -20oC Freezers
Good Manufacturing Practice (GMP) Facility (RWMC)	Cell Harvester
Good Manufacturing Practice (GMP) Facility (RWMC)	Sterile Tube Sealer
Good Manufacturing Practice (GMP) Facility (RWMC)	Sterile Tube Connector
Good Manufacturing Practice (GMP) Facility (RWMC)	Peristaltic Pump
Good Manufacturing Practice (GMP) Facility (RWMC)	ELISA plate reader
Good Manufacturing Practice (GMP) Facility (RWMC)	Radioactivity room
Good Manufacturing Practice (GMP) Facility (RWMC)	Microscopes
Good Manufacturing Practice (GMP) Facility (RWMC)	Centrifuge
Hospital-Imaging Research and Education Service (HI-RES) Facility	Image Analysis and Education Contact: Daniel Dickstein MD FAAP	The Hospital-Imaging Research and Education Service (HI-RES) Facility has two image analysis and education centers, one at Rhode Island Hospital and the other at Butler Hospital. The Rhode Island Hospital site features advanced computing for image analysis, an image processing server, conference room and three offices. The Butler Hospital site consists of two room that house eight computers equipped for image analysis. HI-RES also utilizes Brown University’s high performance computing center (HPC).	Research mission: To foster collaborative imaging research both in/within stakeholder departments and also to foster collaborative links to Brown University campus-based researchers This has the potential to include trainees interested in hands-on research projects as well as hospital-based faculty. Education mission: To bolster the interdisciplinary education of hospital-based trainees in the use of imaging, particularly neuroimaging, to advance the understanding of the biological basis of neurodevelopmental disorders. This will include didactic sessions, journal clubs and hands-on sessions with trainees, including medical residents and PhD- trainees.
Hospital-Imaging Research and Education Service (HI-RES) Facility (Butler Hospital)	Image Analysis and Education Contact: Daniel Dickstein MD FAAP	The Hospital-Imaging Research and Education Service (HI-RES) Facility has two image analysis and education centers, one at Rhode Island Hospital and the other at Butler Hospital. The Rhode Island Hospital site features advanced computing for image analysis, an image processing server, conference room and three offices. The Butler Hospital site consists of two room that house eight computers equipped for image analysis. HI-RES also utilizes Brown University’s high performance computing center (HPC).	Research mission: To foster collaborative imaging research both in/within stakeholder departments and also to foster collaborative links to Brown University campus-based researchers This has the potential to include trainees interested in hands-on research projects as well as hospital-based faculty. Education mission: To bolster the interdisciplinary education of hospital-based trainees in the use of imaging, particularly neuroimaging, to advance the understanding of the biological basis of neurodevelopmental disorders. This will include didactic sessions, journal clubs and hands-on sessions with trainees, including medical residents and PhD- trainees
Imaging Core (RWMC)	Confocal Microscope	Zeiss / LSM 700 confocal microscope	A four laser, point scanning confocal with a single pinhole. It is in an inverted configuration to facilitate live cell imaging. Uses a variable secondary dichroic (VSD) beamsplitter, which enables efficient yet rapid detection of up to four different color signals. This system uses a sliding dichroic mirror to rapidly direct specific wavelengths to selected photodetectors. This technology allows use of the entire emission spectrum for imaging, while simultaneously preventing crosstalk between closely positioned fluorophore emission spectra.
Imaging Core (RWMC)	Optical Microscope	Zeiss / Axioplan 2 optical microscope	The Zeiss Axiovert 200M microscope is an inverted fluorescence microscope with motorized Z-axis acquisition and a filter wheel with Rhodamine, FITC, DAPI, and bright field. Objective lenses include 10x/0.3, 20x/0.4, 40x/1.3 oil, and 63x/1.4 oil DIC. The system is equipped with the AxioVision v4.6.3 acquisition software.
Imaging Core (RWMC)	In Vivo Imaging System	PerkinElmer / IVIS Model 100 Imaging System	Equipped with a Fluorescence Kit, an Anesthesia System, and the Living Image Acquisition/Analysis software. Non-invasively monitor, in real time, bio-luminescence and fluorescence within small animal models and in vitro specimens. The instrument can non-invasively monitor up to 5 mice simultaneously, and monitor in vivo multiple fluorescent and bio-luminescent reporters simultaneously. The IVIS model 100 system is controlled by the Living Image Acquisition/Analysis Software Package, allowing for advanced quantification and analysis of all data acquired from each animal.
Leduc Bioimaging Facility	Bioinformatics Analysis - Molecular Devices, MetaMorph	Software: Molecular Devices, MetaMorph	Software for microscopy automation & image analysis
Leduc Bioimaging Facility	Critical Point Dryer	Ladd Research Industries	Removes liquid from biological specimens for SEM
Leduc Bioimaging Facility	Glow Discharge Unit	Emitech K100X	Adds a charge to make TEM samples hydrophilic
Leduc Bioimaging Facility	Microscope	Olympus MultiPhoton Laser Scanning	Deep optical sectioning of fluorescently labeled samples with SIM photoactivation
Leduc Bioimaging Facility	Microscope	Zeiss Axiovert 200M Fluorescence	Imaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss Axiovert 200M Fluorescence	Imaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss LSM 510 Meta Confocal	Optical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss LSM 710 Confocal	Optical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss Lumar Stereo Fluorescence	Imaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope - Electron	Hitachi S-2700 Scanning Electron Microscope (SEM)	Transmission electron microscopy with PCI Digital Imaging Accessory
Leduc Bioimaging Facility	Microscope - Electron	Philips 410 Transmission Electron Microscope (TEM)	Scanning electron microscopy with AMT Camera Accessory
Leduc Bioimaging Facility	Microtome	Reichert Ultramicrotome	Ultrathin sectioning for TEM
Leduc Bioimaging Facility	Microtome Diamond Knife Set	Diatome DKS	Used on Reichert microtome to cut ultrathin sections for TEM
Leduc Bioimaging Facility	Sputter Coater System	Emitech K550	Covers an EM specimen with a thin layer of conducting material
Leduc Bioimaging Facility	Technical Assistance - Bioimaging	Service	Service to provide Bioimaging Technical Assistance
Leduc Bioimaging Facility	Technical Assistance - Bioimaging Training	Service	Service to provide Bioimaging Training
Leduc Bioimaging Facility	Microscope	Zeiss LSM 800 Confocal	Optical sectioning of samples labeled with fluorescent indicators
Magnetic Resonance Imaging Facility	Magnetic Resonance Imaging (MRI) Scanner	Siemens 3 Tesla Prisma fit	Brain structure and function in normal and clinical populations as well as studies of other body systems, non-invasive animal imaging and materials science.
Marine Science Research Facility	Analyzer - Dissolved Gas Contact: Rodrigue Spinette	Bay Instruments Membrane Inlet Mass Spectrometer- Dissolved Gas Analyzer	Mass Spectrometer: Quantifies dissolved gases
Marine Science Research Facility	Analyzer - Multiparameter Water Analyzer Contact: Rodrigue Spinette	YSI Professional Plus Hand Held Multiparameter Water Meter	Measures temperature, salinity, dissolved oxygen (DO), and pH
Marine Science Research Facility	Analyzer - Nutrient Contact: Rodrigue Spinette	Lachat QuickChem 8500 Flow Injection Nutrient Auto Analyzer	Measures dissolved nutrients in water, Ammonia, Phosphate, Nitrite, Nitrate, and Silicate
Marine Science Research Facility	Aquatic Culture - Algae and Live Feed Room Contact: Ed Baker	Various manufacturers	K-walls, small rearing tanks for live feed, flowing seawater and freshwater
Marine Science Research Facility	Aquatic Culture - Phytoplankton Culture Wheels Contact: Ed Baker	Various manufacturers	Motorized and water driven, clear plexiglass, ambient and experimental temperature control, can accommodate culture bottles of differing sizes (1-3L)
Marine Science Research Facility	Dechlorination System - Freshwater Contact: Ed Baker	Various manufacturers	2 Freshwater dechlorination tanks
Marine Science Research Facility	Disrupter Contact: Rodrigue Spinette	Biospec Mini Bead Beater	Shakes tubes with beads to disrupt cells, DNA , RNA
Marine Science Research Facility	Disrupter Contact: Rodrigue Spinette	Branson Digital Ultasonic Liquid Sonifier	Disrupts cells
Marine Science Research Facility	Environmental Chamber Contact: Ed Baker	EnvironAir Environmental Chamber	100 sq ft Temperature control, Two range 4-24 C, Two range -4-24 C (to simulate polar conditions), On generator back up and emergency monitoring systems. (4 Units)
Marine Science Research Facility	Flowing Seawater System Contact: Ed Baker	Various manufacturers	Raw-Ambient temperature and Filtered- Chilled, Heated, Ambient. UV treated, air supply, emergency monitoring systems
Marine Science Research Facility	Fluorescence Activated Cell Sorter (FACS) Contact: Rodrigue Spinette	Becton Dickinson (BD) Biosciences Influx Flow Cytometer and Cell Sorter	Measures light scatter and fluorescence of cells. Sorts cells based on measured properties.
Marine Science Research Facility	Fluorometer Contact: Rodrigue Spinette	Satlantic Fluorescence Induction Relaxation Fluorometer (FIRE)	Measures variable fluorescence in phytoplankton
Marine Science Research Facility	Fluorometer Contact: Rodrigue Spinette	Turner Designs 10-AU (Chlorophyll) Field Fluorometer	Measures extracted or in vivo chlorophyll fluorescence of samples, Field-portable, can be set up for continuous-flow monitoring or discrete sample analyses
Marine Science Research Facility	Fluorometer Contact: Rodrigue Spinette	Life Technologies Qubit Fluorometer	Quantifies DNA, RNA, and protein
Marine Science Research Facility	Freezer - Walk-in Contact: Ed Baker	-20 C Walk-In Freezer	185 sq ft Long term storage, On generator back up and emergency monitoring systems
Marine Science Research Facility	Homogenizer Contact: Rodrigue Spinette	Polytron Homogenizer PT-10-35-GT	Breaks down plant and animal tissue for analysis, and performs homogenization, dispersion, mixing, and prepares emulsions
Marine Science Research Facility	Cell Counter Contact: Rodrigue Spinette	Sizing and counting of particles suspended in liquid samples	Beckman Coulter Multisizer 4
Marine Science Research Facility	Imaging System - Camera Contact: Rodrigue Spinette	Allied Digital Stingray Firewire Microscope Camera	Captures video and still images (C-mount)
Marine Science Research Facility	Analyzer - Fluid Particle Counter and Imager Contact: Rodrigue Spinette	Fluid Imaging Technologies FlowCam	Imaging Particle Analysis: counts and records images of particles in liquid samples
Marine Science Research Facility	Incubator Contact: Rodrigue Spinette	Percival Incubator/Growth Chamber	Temperature and light controlled incubator for environmental applications
Marine Science Research Facility	Microplate Reader Contact: Rodrigue Spinette	Molecular Devices Spectramax M5	Measures Fluorescence Intensity, Absorbance, Time Resolved Fluorescence, Fluorescence Polarization and Luminescence in cuvettes and multiple sized microplates.
Marine Science Research Facility	Microscope Contact: Rodrigue Spinette	Nikon inverted Microscope	Microscopy: Works with Stingray Camera
Marine Science Research Facility	Microscope Contact: Rodrigue Spinette	Olympus SZX16 Stereo Microscope	Microscopy. Works with Stingray Camera
Marine Science Research Facility	PCR Thermal Cycler Contact: Rodrigue Spinette	Eppendorf Master Cycler Pro	Replicates DNA
Marine Science Research Facility	PCR Thermal Cycler Contact: Rodrigue Spinette	Stratagene QPCR Mx3000P	Analysis of gene expression, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Quantitative PCR Filters- FAM/Syber Green, Rox, Hex, CY3, CY5
Marine Science Research Facility	Photoperiod controller Contact: Ed Baker	Various manufacturers	Wattstopper controller(Blount), Various individual timers
Marine Science Research Facility	Pier Access Contact: Ed Baker	Access to Graduate School of Oceanography pier	Access to pier for deployment, collection, testing. Water depths 18-15 feet to intertidal zone
Marine Science Research Facility	Radiometer Contact: Rodrigue Spinette	Biospherical Instruments Quantum Scalar Laboratory (QSL) Radiometer - PAR Light Meter	Measures Photosynthetically Active Radiation (PAR)
Marine Science Research Facility	Shaker Contact: Rodrigue Spinette	Thermo Max-Q Orbital Shaker Table	Orbital shaker with 18x24 in platform and variety of clamps
Marine Science Research Facility	Shaker Contact: Rodrigue Spinette	Thermo Max Q Incubated Shaker	Heated incubated shaker
Marine Science Research Facility	Spectrometer Contact: Rodrigue Spinette	Ocean Optics Jaz Spectrometer	Optical sensing instrumentation that measures light wavelengths. Its unique features and expandable platform makes it uniquely suited for field applications, remote sensing, process flow and quality assurance.
Marine Science Research Facility	Spectrophotometer Contact: Rodrigue Spinette	Thermo Scientific NanoDrop 1000	Microvolume UV-Vis spectrophotometer that quantifies DNA, RNA, and protein from small 1-2 microliter sample size
Marine Science Research Facility	Tank - Laminar Flow Contact: Ed Baker	Laminar Flow Tank	1000 gal, Seawater or Freshwater, Multiple speeds with precision control. Experimental chamber visable from 5 sides
Marine Science Research Facility	Tank - Mesocosm Contact: Ed Baker	Various manufacturers	10, 5 ft deep outdoor mesocosms, with available raw ambient seawater flow
Marine Science Research Facility	Vacuum Manifold Contact: Rodrigue Spinette	Vacuum Filter Manifold	Allows for filtration of 5 ports simultaneously, 25 and 47 mm filter cups available
Marine Science Research Facility	Worksation - Marine General Wet Lab Contact: Ed Baker	Various manufacturers	3 Buildings, 7,000 sq ft indoor, and nearly unlimited outdoor space, Multiple insulated tank sizes, various sized aquaria, possible to perform simultaneous replicates
Marine Science Research Facility	Workstation - Marine Pathology and Transgenics Laboratory and Systems Contact: Ed Baker	Various manufacturers	Ozone treated effluent and separate effluent drain
Marine Science Research Facility	Microscope	Epifluorescence and phase microscopy with digital camera system	Nikon Eclipse Ni epifluorescence microscope
Marine Science Research Facility	Gas Chromatograph - Mass Spectrometer (GC - MS) Contact: David Adelman	Identifies and enumerates chemical constituents of samples	Agilent Technologies 7890B/5977A GC/MSD
Marine Science Research Facility	Gel Imager Contact: Rodrigue Spinette	Fluorescence gel imaging system	Carestream Molecular Imaging Gel Logic 212 Pro
Marine Science Research Facility	Cell Counter Contact: Rodrigue Spinette	Sizing and counting of particles suspended in liquid samples	Beckman Coulter Multisizer 4
Marine Science Research Facility	Microscope Contact: Rodrigue Spinette	Epifluorescence and phase microscopy with digital camera system	Nikon Eclipse Ni epifluorescence microscope
Marine Science Research Facility	Gel Imager Contact: Rodrigue Spinette	Fluorescence gel imaging system	Carestream Molecular Imaging Gel Logic 212 Pro
Mass Spectrometer Analytical Facility	Mass Spectrometer Contact: Alberto Saal	Thermo Scientific Multi-collector inductively coupled plasma mass spectrometer, ICP-MS, Neptune Plus	This is a multi-collector ICP-MS equipped with nine Faraday cups and eight ion counters, which allows us to monitor multiple masses simultaneously providing precise isotope ratio measurement.
Mass Spectrometer Analytical Facility	Mass Spectrometer Contact: Alberto Saal	Thermo Scientific Quadrupole inductively coupled plasma mass spectrometer, ICP-MS, X-series-2	This is a single collector ICP-MS that allows us to measure precise elemental composition at sub-ppb level concentration.
Mass Spectrometer Analytical Facility	Laser Ablation Contact: Alberto Saal	Photon-machines Analyte G2, 193 nm excimer laser ablation	This 193 nm wave-length excimer laser allows us to perform in-situ analysis on a solid sample with a beam diameter as small as 3 �m. To determine the elemental abundances the laser is coupled with the single collector inductively coupled plasma mass spectrometer ICPMS and to determine the isotope ratios the laser is coupled with multi collector ICPMS.
Mass Spectrometer Analytical Facility	Clean lab, Trace metal free Contact: Alberto Saal	Pico Trace	This Clean Lab is equipped with Millipore water filtration system that provides greater than 18MΩ Milli-Q water. The working stations in this Clean Lab meet ISO class 4 standard (equivalent to FS class 10) allowing us to perform ultra-low blank chemical analysis.
Mass Spectrometry Facility	Gas Chromatograph - Mass Spectrometer (GC - MS)	Hewlett-Packard (Agilent) GCD 1800C	This system is suitable for separation of complex mixtures by gas chromatography (GC) and identification by mass spectrometry. It is limited to low molecular weight and volatile molecules (mass range 450 Da).
Mass Spectrometry Facility	Liquid Chromatography - Mass Spectrometer (LC - MS)	Agilent 6530 Mass TOF	This system consist of Agilent 1260 infinite HPLC and Agilent 1260 infinite nanoglow LC/chipcube nanoelectrospray MS interface, and 6530 Accurate Mass Q-TOF mass spectrometer . This instrument can detect and identify compounds in amounts smaller than two trillionths of a gram (2 picograms), making the Agilent 6530 a powerful tool for food safety, toxicology and other measurements where minute amounts of compounds must be identified.
Mass Spectrometry Facility	Mass Spectrometer	JEOL JMS-600H double focusing magnetic sector	The JMS-600H is a compact double-focusing, high-resolution, magnetic sector mass spectrometer. This instrument is equipped with electron impact ionization (EI), Chemical Ionization (CI), and fast atom bombardment ionization (FAB) for characterization of synthetic organic, inorganic, and biological molecules. This instrument is also used for routine exact mass measurement of organic molecules.
Mass Spectrometry Facility	Mass Spectrometer	Thermo LXQ linear ion trap with Surveyor HPLC system	The LXQ has capabilities similar to the conventional 3D ion trap such as LCQ Deca. It is based on linear ion trap technology that has faster cycle time. It is capable of data-dependent LC/MSn analysis.
Mass Spectrometry Facility	Mass Spectrometer	Thermo LCQ Deca XP Max ion trap with Shimadzu HPLC system	The LCQ Deca XP Max is equipped with electrospray (ESI) and APCI ionization sources. It is capable of mass analysis of a broad range of molecules that are relatively polar, nonvolatile and thermally labile. This instrument is used for routine molecular weight determination of compounds from organic, inorganic, natural products, small proteins and peptides, and oligonucleotides.
Mass Spectrometry Facility	Mass Spectrometer	The Bruker autoflex Speed is a linear time-of-flight (TOF) mass spectrometer equipped with a matrix-assisted laser desorption ionization (MALDI) ion source. This instrument is routinely used for analysis of organic molecules, natural products, and macromolecules, including recombinant proteins, oligonucleotides, polysaccharides and synthetic polymers.	Bruker Autoflex Speed Linear (L) Matrix Assisted Laser Desorption Ionization-Time of Flight mass spectrometer (MALDI-TOF MS).
Mass Spectrometry Facility	Gas Chromatograph - Mass Spectrometer (GC - MS)	This system is suitable for separation of complex mixtures by gas chromatography (GC) and identification by mass spectrometry. It is limited to low molecular weight and volatile molecules (mass range 1050 Da).	Agilent 5977A
Media Prep Kitchen	Media Prep Kitchen for Drosophila	Service	The Brown Fly Facility is dedicated to providing investigators with high quality media for Drosophila research. The media kitchen is equipped with a food service quality steam kettle fitted with stirring unit, a Steris autoclave and a Lancer Washer fitted with custom racks for glass vials. Media is dispensed using Filamatic and Materflex/ Digistalic pumps. In the centralized kitchen, a standard cornmeal, sucrose, yeast medium is prepared and dispensed into different sized culture vessels. Media is prepared in a steam-jacketed food kettle and pumped into trays of glass vials (10ml), plastic vials (10ml) or into plastic bottles (30ml) depending on research needs. Media is prepared according to a strict protocol that ensures consistency in diet and the absence of any bacterial, fungal or insect contamination. Researchers using glass vials return them to the facility where they are autoclaved, washed, and filled again.
Molecular Biology and Imaging Core	Fluorescence Activated Cell Sorter (FACS)	Thermo Scientific Attune NXT	Analytical flow cytometer: 3 lasers, 11 colors, with 96 well plate handler capability
Molecular Biology and Imaging Core	Confocal Microscope	Andor CSU-W1 spinning disk confocal system	The Spinning disk confocal microscope is a Nikon Ti-E (inverted) with Perfect Focus and motorized stage, with an Andor Zyla 4.2 plus SCMOS camera, an Andor CSU-W1 spinning disk with 405, 488 and 561 nm laser lines, as well as a SpectraX LED widefield light source and controlled by NIS-Elements software. This system is suitable for fast confocal imaging and live cell imaging, with low phototoxicity and long term focus stability. A stage incubator with CO2 and temperature control is available for maintenance of physiological conditions during live cell imaging.
Molecular Biology and Imaging Core	Fluorescence Activated Cell Sorter (FACS)	Becton Dickinson (BD) Biosciences FACSCanto	Analytical Flow Cytometer: 2 lasers, 6 colors
Molecular Biology and Imaging Core	Gel Imager	Bio-Rad Chemidoc XRS	The ChemiDoc XRS+ system is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab software to optimize imager performance for fast, integrated, and automated image capture and analysis of various samples.
Molecular Biology and Imaging Core	Gel Imager	Bio-Rad Molecular Imager FX system	Imager with 50 micron resolution and a 5 order of magnitude linear dynamic range for fluorescence and radioisotopic imaging. You can also image and accurately quantitate chemiluminescent samples.
Molecular Biology and Imaging Core	Magnetic cell sorter	Miltenyi AutoMACS	Automated cell sorter, for separating cell suspensions labeled with magnetic beads
Molecular Biology and Imaging Core	Microplate Reader	Molecular Devices Spectramax Gemini EM Fluorescence Microplate Reader	Enables top and bottom reading of microplates over a greater range of fluorescence intensities�all without the use of filters.
Molecular Biology and Imaging Core	Microplate Reader	Perkin Elmer TopCount NXT Microplate Scintillation and Luminescence Counter	TopCount NXT analyzes two, six, or twelve samples at a time, and counts samples in 24-, 96-, and 384-well microplates, as well as microcentrifuge tubes. It can count gammas, betas, or luminescent samples.
Molecular Biology and Imaging Core	Microscope	Leica MZ FLIII Stereo Fluorescent dissection microscope	Dissection microscope with Leica color camera DC300F.
Molecular Biology and Imaging Core	Microscope	Nikon 80i Upright Fluorescence Microscope	Upright microscope with color CCD camera Spot Insight 2
Molecular Biology and Imaging Core	Microscope	Nikon TE2000E Inverted fluorescence,	A live cell imaging microscope, with cooled CCD camera Roper CoolSnap HQ
Molecular Biology and Imaging Core	Microscope	Zeiss AxioImager M2 Upright Microscope,	Upright microscope with color CCD camera AxioCam MRC.
Molecular Biology and Imaging Core	Microscope	Nikon TE2000E Inverted fluorescence,	A Multicolor fluorescence widefield microscope, with stage incubator, specialized in live cell imaging
Molecular Biology and Imaging Core	PCR Thermal Cycler	Applied Biosystems ABI 7500	96-well quantitative PCR
Molecular Biology and Imaging Core	Spectrophotometer	Bio-Rad smartspec	90-260 V, UV/visible benchtop spectrophotometer for nucleic acid and protein quantitation, wavelength range 200�800 nm, built-in thermal printer
Molecular Biology and Imaging Core	Spectrophotometer	Thermo Scientific NanoDrop 2000	A full spectral microvolume UV-Vis analysis spectrophotometer for measuring DNA, RNA, and�protein.
Molecular Biology and Imaging Core	Suspension Array System	Bio-Rad BioPlex 200	Detection and quantification of multiple analytes (proteins and peptides, or nucleic acids) in a single sample volume.�
Molecular Biology and Imaging Core	Cryostat	Frozen tissue sections	Thermo Shandon Cryotome E
Molecular Biology and Imaging Core	Microtome	Paraffin embedded tissue sections	Thermo Shandon Finesse ME
Molecular Biology and Imaging Core	Histology/Tissue Processing - Paraffin Embedding Workstation	Tissue processing	Thermo Shandon Histocenter 2
Molecular Biology and Imaging Core	Centrifuge - Cyto	Thin layer preparation from cell suspensions	Thermo Scientific Cytospin 4 Cytocentrifuge
Molecular Biology and Imaging Core	Nanoparticle counter	Malvern Nanosight NS300	Analysis of size distribution and concentration of nanoparticles from 10nm to 2000nm in diameter. A 532nm green laser also allows the detection of red fluorescent particles. A syringe pump allows sample analysis under constant flow, increasing reliability and reproducibility of data.
Molecular Biology and Imaging Core	Gel imager	The ChemiDoc MP system is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab software to optimize imager performance for fast, integrated, and automated image capture and analysis of various samples.	Bio-Rad Chemidoc MP
Molecular Biology and Imaging Core	Cell counter	The Auto T4 is a PC-based instrument for one-step 4x bright field image capture and analysis. This state-of-the-art cell counter performs count, size, and Trypan Blue viability analyses that are 10x faster and more accurate than manual counting. This instrument is ideal for cell lines and purified primary cells, including MCF-7 breast cancer cells, PC3 prostate cancer cells, and 1600 other cell types, due to its advanced software that assesses clumpy cells and omits debris	Nexcelom Cellometer
Molecular Biology and Nanomedicine Facility	Microplate Reader Contact: Cherie Charbonneau	Molecular Devices SpectraMax M2e plate reader	Features top and bottom read capability for absorbance, fluoresence, luminescence, and time-resolved fluorescence.
Molecular Biology and Nanomedicine Facility	Hybridization Oven Contact: Cherie Charbonneau	Fisher Scientific Isotemp hybridization chamber	Temperature range of +7C to 85C. Includes a rotisserie.
Molecular Biology and Nanomedicine Facility	Shaker Contact: Cherie Charbonneau	Lab Companion SI-600 Incubated Shaker	Bacterial culture shaker with a temperature of ambient to +60C.
Molecular Biology and Nanomedicine Facility	Luminometer Contact: Cherie Charbonneau	Promega Glomax 20/20 luminometer�with printer	Ultrasensitive luminescence detection in a single microcentrifuge tube (1.5ml) format.
Molecular Biology and Nanomedicine Facility	PCR Thermal Cycler Contact: Cherie Charbonneau	Bioer Life ECO thermal cycler	This thermal cycler has a 96 well format with a 2C/sec ramp rate.
Molecular Biology and Nanomedicine Facility	PCR Thermal Cycler Contact: Cherie Charbonneau	Applied Biosystems ProFlex thermal cycler	This thermal cycler has a 3x32 well format that allows for 3 separate programs to be run. The ramp rate is 6C/sec.
Molecular Biology and Nanomedicine Facility	PCR Thermal Cycler Contact: Cherie Charbonneau	Applied Biosystems Veriti thermal cycler	This thermal cycler has a 96 well format with 3.9C/sec ramp rate.
Molecular Biology and Nanomedicine Facility	Imaging system Contact: Cherie Charbonneau	LI-COR Odyssey Classic Infared Imaging system	This near-infared fluorescent detector can be used for quantitative western blots, gel shift assays, coomassie stains, tissue section and small animal imaging.
Molecular Biology and Nanomedicine Facility	Gel Imager Contact: Cherie Charbonneau	UVP GelCam 310 Bioimaging digital gel documentation system	High resolution 2.0 GelCam 310 CCD with manual zoom lens for fluorscent and colorimetric gel imaging. EtBr filter included.
Molecular Biology and Nanomedicine Facility	PCR Thermal Cycler Contact: Cherie Charbonneau	MJ Opticon 2 real-time PCR system.	This 96-well system accepts low-profile tubes or plates. There are two fluorophore channels with emission spectra in the 523-543 nm range and 540-700nm.
Molecular Biology and Nanomedicine Facility	Incubator Contact: Cherie Charbonneau	(4) NuAire IR water-jacketed CO2 incubators (NU-8500)	This incubator provides an optimal in-vitro growth environment for both cell and tissue culture while minimizing dessication through a closed loop HEPA filtration system.
Molecular Biology and Nanomedicine Facility	Biological Safety Cabinet Contact: Cherie Charbonneau	(4) NuAire Bio Safety Cabinets (Class II, Type A/B3)	These biological safety cabinets reduce exposure to airborne biological or particulate chemical agents in low to moderate risk-hazard research and/or drug preparations.
Molecular Biology and Nanomedicine Facility	Centrifuge Contact: Cherie Charbonneau	Sorvall Legend X1R centrifuge	Process samples for diverse laboratory applications with rotors for 1.5ml eppendorf tubes, 15, and 50ml conical tubes. Refrigerated with a max speed of 152000 rpm.
Molecular Biology and Nanomedicine Facility	Autoclave Contact: Cherie Charbonneau	Amerex HVE-50 top loading autoclave sterilizer	This is a 50L, self-contained, portable, top-loading autoclave with auto-exhaust and warming cycles.
Molecular Biology and Nanomedicine Facility	Microscope Contact: Cherie Charbonneau	Nikon Eclipse TS-100F Inverted Microscope	This phase contrast microscope used for tissue culture is also equipped with FITC and TRITC filters to capture fluorescent images in SPOT imaging software.
Molecular Biology and Nanomedicine Facility	Microscope Contact: Cherie Charbonneau	Nikon Eclipse 90i Upright Research Microscope	This microscope is equipped with two cameras (color and monochromatic) and is ideal for brightfield and/or epi-fluorescent images of whole tissues etc with 4x, 10x, 20x and 40x dry objectives. The filter cubes available are DAPI, FITC, and TRITC.
Molecular Biology and Nanomedicine Facility	Flow Cytometer Contact: Cherie Charbonneau	Becton Dickinson - Accuri	This system is equipped with a blue and red laser, two light scatter detectors, and fluorescence detectors with optical filters optimized for FITC, PE, PerCP, and APC. The user does not need to adjust detector voltages and there is a wide dynamic range of digitally collected data (7.2 decades).
Molecular Biology and Nanomedicine Facility	Bioanalyzer Contact: Cherie Charbonneau	Invitrogen Luminex 200 with xMap technology	This is a versatile, efficient standard in multiplexing with the ability to use magnetic or polystyrene beads on up to 100 targets/sample.
Molecular Biology and Nanomedicine Facility	pH Meter Contact: Cherie Charbonneau	Orion pH meter 920	pH range of -2 to 19.99 and oxygen range of -2 to 19.99ppm. Autocalibration buffers of 4.01, 7, and 10.01.
Molecular Biology and Nanomedicine Facility	pH meter Contact: Cherie Charbonneau	Hanna Instruments 2209	This pH meter features manual pH calibration and temperature compensation.
Molecular Biology and Nanomedicine Facility	Microtome Contact: Cherie Charbonneau	Thermo Scientific Shandon Finesse 325 manual microtome	With a lightly balanced flywheel it is ideal for routine paraffin sectioning.
Molecular Biology and Nanomedicine Facility	Cutter Contact: Cherie Charbonneau	Buehler-Isomet Cutter	The IsoMet Low Speed Cutter is a precision sectioning saw designed for cutting various types of materials with minimal deformation. Its low kerf loss capability and great versatility in holding all types of sample shapes and configurations, gives today's laboratory a precision sectioning tool capable of cutting viturally any material including brittle or ductile metals, composites, cements, laminates, plastics, electronic devices and biomaterials. The Cutter is equipped with a diamond studded carborundum wheel and Buehler Ecomet 4 grinder/polisher with Automet 2 powerhead.
Molecular Biology and Nanomedicine Facility	Imaging system Contact: Cherie Charbonneau	PerkinElmer FMT 4000 Fluorescence Tomography System.	The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. The system comes with four excitation laser channels (635, 680, 750, and 790 nm) and is useful for a range of applications including oncology, inflammation, and cardiovascular disease. It is ideal for researchers who are well-versed in 3D fluorescence tomography and require the widest range of in vivo applications and imaging agents.
Molecular Biology and Nanomedicine Facility	Imaging system Contact: Cherie Charbonneau	Faxitorn Pre-clinical imaging system	Ultra-high resolution x-ray imaging is an important tool in investigating�a variety of disease states. From metastatic cancer to arthritis and�osteoporosis, small animal models are commonly used. Both in vivo and�ex vivo planar imaging is used to screen, track, and evaluate structural�changes in these studies. Cabinet x-ray systems allow researchers to�take images directly in the vivarium to protect the integrity of the colony. �These planar imaging systems are less expensive, subject animals to�lower doses, and provide faster results than microCT systems.
Molecular Biology and Nanomedicine Facility	Incubator Contact: Cherie Charbonneau	GQF 1502 Sportsman egg incubator	This is a complete incubator and hatching system with 3 automatically turned racks. It has an accurate digital thermostat with LCD of humidity and temperature.
Molecular Biology and Nanomedicine Facility	Homogenizer Contact: Cherie Charbonneau	Fisher Scientific, Powergen 125 Tissue Homogenizer	Process volumes from 0.03 to 100mL. Variable speed control to 30,000rpm for efficient cell disruption. Disposable plastic generators eliminate sample cross-contamination. Flat-bottom stainless-steel generators process liquid or soft tissues.
Molecular Biology and Nanomedicine Facility	Microscope Contact: Cherie Charbonneau	Olympus SZ61 Zoom Stereomicroscope	Greenough design with two optical paths inclined at an inward angle. Magnification range 0.67X to 4.5X; zoom ratio 6.7:1; FN 22. Working distance of 100mm; observation tube angle 45 degrees; right and left eyepiece tubes interlocked; interpupillary distance adjustment 50-76mm; forward positioned zoom adjustment knobs with zoom magnification graduations. With 0.5x cmount for documentation.
Molecular Biology and Nanomedicine Facility	Fume Hood Contact: Cherie Charbonneau	Thermo Scientific Hamilton SafeAire II	Chemical hood and ultra-high vacuum system for organic synthesis
Molecular Biology and Nanomedicine Facility	Evaporator Contact: Cherie Charbonneau	Buchi R-124 Rotovapor	Rotary evaporator comes complete with a 45 degree water condenser and a 1L condensing and evaporating flask.
Molecular Biology and Nanomedicine Facility	Circulator Contact: Cherie Charbonneau	VWR Recirculating Chiller, Model 1160A	Stable cooling for many common heat removal applications such as rotary evaporators and vacuum systems (-10 to 40C).
Molecular Biology and Nanomedicine Facility	High Performance Liquid Chromatography (HPLC) Contact: Cherie Charbonneau	Agilent Technologies, 1260 Infinity HPLC system	A maximum pressure of 600 bar to utilize smaller particle size columns for higher resolution and faster separations.
Molecular Biology and Nanomedicine Facility	Disrupter Contact: Cherie Charbonneau	Qsonica 700W sonicator with 5.5" cup horn	This sonicator has full amplitude control from 1-100%.
Molecular Biology and Nanomedicine Facility	Imaging system Contact: Cherie Charbonneau	Xtreme back illuminated 4MP with x-ray for small animal imaging	High sensitivity luminescence, fluorescence, radioisotopic, and radiographic imaging for up to 5 mice at a time. Isofluarne and temperature controlled chamber for the mice.
Molecular Biology and Nanomedicine Facility	PCR Thermal Cycler, Digital Contact: Cherie Charbonneau	RainDrop Digital PCR by RainDance	The RainDrop is composed of a Source instrument that can generate 10million droplets/sample and the Sense instrument, which can detect whether the PCR reactions are positive or negative for your fluorophore. Multiplexing is possible for the 8 samples that are run at a time on the microfluidics chip.
Molecular Biology and Nanomedicine Facility	PCR Thermal Cycler Contact: Cherie Charbonneau	BioRad CFX96 Real-Time PCR system	This real-time PCR instrument allows for up to 5-target multiplexing in sample volumes as small as 10ul. It also has a thermal gradient feature in a 96-well format.
Molecular Biology and Nanomedicine Facility	Spectrophotmeter Contact: Cherie Charbonneau	Thermo Scientific NanoDrop 2000c	This is a full spectrum, UV-Vis spectrophotometer used to quantify and assess the purity of DNA, RNA, protein, and more at sample volumes as low as 0.5ul.
Molecular Biology and Nanomedicine Facility	Bioreactor Contact: Cherie Charbonneau	Flexcell FX5000 Tension System	This is a computer-regulated bioreactor that uses vacuum pressure to apply either cyclic or static strain to cells cultured on flexible-bottomed culture plates.
Molecular Biology and Nanomedicine Facility	Lyophilizer Contact: Cherie Charbonneau	Labconco FreeZone Plus 2.5L Cascade Benchtop Freeze Dry System	This system is for light sample loads with low eutectic points. It can remove up to 1.8L of water in 24hrs and holds 2.5L of ice before defrosting is required.
Molecular Characterization Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Agilent NMRS 500 with OneNMR probe	Optimized for small molecule NMR
Molecular Characterization Facility	Nuclear Magnetic Resonance (NMR) Spectrometer Contact: Dr. Al Bach	Agilent NMRS 500 with OneNMR Probe	NMR Spectroscopy
Molecular Characterization Facility	Nuclear Magnetic Resonance (NMR) Spectrometer Contact: Dr. Al Bach	Bruker Avance III 300 with BBO probe	Optimized for small molecule NMR
Molecular Characterization Facility	Mass Spectrometer Contact: Dr. Al Bach	ABSciex Qtrap 4500 Triple Quadrapole LC/MS	Has Shimadzu HPLC system attached
Molecular Core (RWMC)	Sequence Detection System	Applied Biosystem / PRISM 7000 Sequence Detection System	The ABI7000 Sequence Detection System (Q-PCR / RT-PCR) is a sequence detection instrument capable of quantitative and qualitative detection with fluorescent-based PCR chemistries. This instrument is capable of quantitative detection using real-time analysis, and qualitative detection using end-point and dissociation-curve analysis. It can be used with TaqMan probe-based chemistry or intercalating dyes such as SYBR Green. The 7000 SDS instrument combines thermal cycling, fluorescence detection, and application specific software. It detects accumulated polymerase chain reaction (PCR) product cycle-by-cycle, thus making quantification available immediately after completion of PCR, without the need for further process analysis. The instrument utilizes a 96 block configuration.
Molecular Core (RWMC)	Molecular Imager	Bio-Rad / ChemiDoc Molecular Imager	A gel imaging system which is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab™ software and can accommodate a wide array of samples, from large polyacrylamide gels to small agarose gels and various blots. The system is an ideal accompaniment to PCR, purification, and electrophoresis systems, enabling image analysis and documentation of restriction digests, amplified nucleic acids, genetic fingerprinting, RFLPs, and protein purification and characterization.
Molecular Pathology Core	Tissue Processing Contact: Paula Weston, M.A.	Service	Paraffin Processing - automated and manual, Placing tissue in cassettes, Glycol Methacrylate Processing, Routine TEM processing, Enhanced contrast TEM, Immunogold labeling
Molecular Pathology Core	Sectioning Contact: Paula Weston, M.A.	Service	Paraffin sectioning, Glycol sectioning Frozen prep and sectioning, TEM ultrathin sectioning
Molecular Pathology Core	Tissue Processor Contact: Paula Weston, M.A.	Leica ASP300 S AutomatedTissue Processor	Tissue processing for paraffin embedding
Molecular Pathology Core	Paraffin Embedding Center Contact: Paula Weston, M.A.	Leica EG1150C Paraffin Embedding Center	Paraffin embedding
Molecular Pathology Core	Automated Microtome Contact: Paula Weston, M.A.	Microm HM 355S Automated Microtome	Paraffin sectioning
Molecular Pathology Core	Automated Microtome Contact: Paula Weston, M.A.	Leica RM2265 Automated Microtome	Paraffin and plastic sectioning
Molecular Pathology Core	Cryostat Contact: Paula Weston, M.A.	Leica CM3050S Cryostat	Sectioning of fixed and unfixed frozen samples
Molecular Pathology Core	Vibratome Contact: Paula Weston, M.A.	Leica VT 1000S Vibratome	Sectioning of fixed and unfixed samples
Molecular Pathology Core	-80 degree C Freezer Contact: Paula Weston, M.A.	Revco -80 C Freezer	Sample storage
Molecular Pathology Core	Light microscope with projector Contact: Paula Weston, M.A.	Nikon Eclipse 50i light microscope with a projector	Collaborative analyses of histological slides and digital imaging capability
Molecular Pathology Core	Laser Capture Microdissection Contact: Paula Weston, M.A.	Arcturus PixCell IIe Laser Capture Microdissection	Capture of specific cell types for RNA, DNA and Protein analysis
Molecular Pathology Core	Slide scanner Contact: Paula Weston, M.A.	Aperio ScanScope CS slide scanner	This microscope uses a 20x objective to produce high-resolution digital scans of histological slides.
Molecular Pathology Core	Staining Contact: Paula Weston, M.A.	Service	H&E staining Cat 1 and 2 staining, PAS staining, Lectin staining, TUNEL staining, Immunolabeling, TEM heavy metal staining
Molecular Pathology Core Laboratory	Bioanalyzer	Agilent Bioanalyzer 2100	The Agilent 2100 Bioanalyzer system provides sizing, quantitation and quality control of DNA, RNA, proteins and cells on a single platform, providing high quality digital data.
Molecular Pathology Core Laboratory	Biological Safety Cabinet	HEPA filter and NuAire laminar flow hood	Filter capable of removing 99.97% of particles greater than 0.3 micronss.
Molecular Pathology Core Laboratory	Biospecimen Banking - Freezer	ThermoForma Freezer - 80 C #8606	Sample storage
Molecular Pathology Core Laboratory	Biospecimen Banking - Freezer	ThermoForma Freezer -20 C #3801	Sample storage
Molecular Pathology Core Laboratory	Biospecimen Banking - Freezer	ThermoForma Refrigerator #3771	Sample storage
Molecular Pathology Core Laboratory	Biospecimen Banking - Refrigerator	ThermoForma Ultra 932 Lo Freezer -80 C (2)	Sample storage
Molecular Pathology Core Laboratory	Centrifuge	Eppendorf 5424 Microcentrifuge	Aerosol-tight rotor. Max rcf: 20,238 x g. Automatic lid opening following application sequence. Low access height: 23 cm. Short spin, rpm/rcf setting as required
Molecular Pathology Core Laboratory	Centrifuge	ThermoForma refrigerated Microcentrifuge	Working temperatures from -5 C to +40 C.
Molecular Pathology Core Laboratory	Cryostat	Leica Cryostat CM1850	Frozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.
Molecular Pathology Core Laboratory	Histology/Tissue Processing - Balance	Mettler (PB303-S) semimicro balance	Mass range of 0.01 mg- 120 g.
Molecular Pathology Core Laboratory	Histology/Tissue Processing - Histobath	Fisher Histobath 134	Prevents development of microscopic ice crystals and sample distortion.
Molecular Pathology Core Laboratory	Histology/Tissue Processing - Microwave Oven	Amana (RFS18MPS) Microwave Oven	Tissue microwave fixation.
Molecular Pathology Core Laboratory	Histology/Tissue Processing - Microwave Oven	GE Microwave oven (JE1460BF001)	Tissue microwave fixation.
Molecular Pathology Core Laboratory	Imaging System - Camera	Polaroid camera	Instant recording of gels.
Molecular Pathology Core Laboratory	Imaging System - Slide Scanner	Aperio ScanScope Slide Scanner CS2	Generates full color, high resolution digital images (cells, tissues and tissue arrays). 5 slide capacity. Image analysis software available. Stored and catalogued in searchable image data base.
Molecular Pathology Core Laboratory	Incubator	Fisher Scientific Dry Bath Incubator	Precise temperature control for temperatures up to 130 C. Built in temperature sensing probe for improved temperature accuracy and control.
Molecular Pathology Core Laboratory	Laser Capture Microdissection System	Arcturus XT Laser Capture Microdissection System	Automated IR and UV laser capture. Microdissection and cutting of cells for RNA, DNA and protein isolation. One modular platform with laser capture and cutting. Optional live-cell modules and camera. Any slide type. Wide range of objectives available, 2x-100x dry and 100x oil immersion.
Molecular Pathology Core Laboratory	Microscope	Olympus Fluorescent Microscope BX41	Image Pro Imaging Software. Excitation available 330-385nm, 460-490nm, 510-550nm. Magnifications of 20,40, 100, 200 power. Both reflected light and sample fluorescence may be viewed through and recorded at the microscope.
Molecular Pathology Core Laboratory	Microscope	Olympus BX41 General Use Microscope	Optical system: UIS2. Built in transmitted Koehler illuminator, 6V/30W bulb. Stage height movement by roller guide, stroke per rotation: 36.8mm. Full stroke range: 25mm. FN20, tube inclination 30 degrees. Stage size: 188 x 134 mm.
Molecular Pathology Core Laboratory	Microtome	Finesse 325 Microtome	Used to prepare samples for observation under transmitted light or electron radiation. Microtome material varies depending on the specimen being sliced and the desired thickness of the sections cut.
Molecular Pathology Core Laboratory	PCR Thermal Cycler	Bio-Rad C1000 Touch Thermal Cycler	The C1000 Touch thermal cycler offers superior performance and a large color touch screen for easy programming. This fully modular platform is able to accommodate different throughput needs with easily interchangeable reaction modules that swap in seconds without tools. Each PCR module has a fully adjustable heated lid that supports a wide range of vessels and sealers, including low-profile and standard-height PCR plates.
Molecular Pathology Core Laboratory	pH Meter	Accumet pH meter	pH meter.
Molecular Pathology Core Laboratory	Robotic Workstation - Barcoding	Ventana Discovery System	Automated staining module using bar code technology. Total automation in IHC staining of frozen/ paraffin embedded tissue, FISH and ISH using DNA, RNA or oligonucleotide probes on tissue or microarrays (gene expression).
Molecular Pathology Core Laboratory	Spectrophotometer	Eppendorf BioPhotometer	50 microliter volumes. Automatic calculation of dilution factors. Measures wave lengths: 230, 260, 280, 340, 405, 490, 550, 595, 650 nm. Spectral bandwidth: 5nm at 230-340nm, 7nm at 405-650nm. Photometric random error +/- 0.002A at 0A, +/- 0.005A at 1A.
Molecular Pathology Core Laboratory	Suspension Array System	Beecher Manual Tissue Microarrayer	Generates multiple specimen slides that can contain hundreds of individual tissues. Up to 100 tissue cores per paraffin block. Use for same histochemical and molecular detection techniques as with regular sections.
Molecular Pathology Core Laboratory	Vacuum Oven	Napco Model 5831 vacuum oven	Capacity: 0.45 cu ft. Temp range: 35 C to 200 C. 30-in Hg vacuum capability. Vacuum bleed valves permit pulling of vacuums as high as 30 inches H. Full view observation window with latched door and built in safety to prevent thermal runaway.
Molecular Pathology Core Laboratory	Waterbath	PolyScience refrigerated/heated (9106) circulating waterbath	These quality baths are ideal for calibration, electrophoresis, rotary evaporation, viscometry, or other applications requiring cooling or heating. Standard Digital Controller Bath features ±0.05°C temperature stability down to -20°C
Molecular Pathology Core Laboratory	PCR Thermal Cycler	Available for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies.	Agilent Mx3005P qPCR System
Molecular Pathology Core Laboratory	Spectrophotometer	Thermo Scientific NanoDrop 2000	Wide spectral range (190-840nm) for measuring a variety of samples types. Only requires 0.5 - 2 µL of your sample. Pre-configured methods for DNA, Protein A280, Microarray, Protein and Labels, Pierce 660, Bradford, BCA, and Lowry. No dilutions required, even for highly concentrated samples. Fast measurement time of less than 5 seconds, 10 -15 seconds from sample pipetting to wiping the pedestal clean.
Molecular Pathology Core Laboratory	Imaging System- Image Analysis Software	Allows processing and analysis of a 2D and 3D (limited) images (brightfield/IHC, fluorescent, other) for qualitative and quantitative in both spatial and frequency domains	Media Cybernetics Image-Pro Premier
Mouse Transgenic and Gene Targeting Facility	Biological Safety Cabinet	NuAire Safety Cabinets Class 2 Type A/B3	Transgenics and gene targeting safety cabinets (2 units)
Mouse Transgenic and Gene Targeting Facility	Centrifuge	Thermo IEC Centra CL3R Refrigerated Centrifuge	Transgenics and gene targeting refrigerated centrifuge
Mouse Transgenic and Gene Targeting Facility	Electroporation System	Bio-Rad Gene Pulsar II	Transgenics and gene targeting electroporation system
Mouse Transgenic and Gene Targeting Facility	Freezer	Custom BioGenic Systems Liquid Nitrogen (LN2) Freezer	Transgenics and gene targeting liquid nitrogen freezer
Mouse Transgenic and Gene Targeting Facility	Freezer	Thermo Fisher Scientific -80 C	Transgenics and gene targeting -80 C freezer
Mouse Transgenic and Gene Targeting Facility	Freezer	Frigidaire -20 C Freezer	Transgenics and gene targeting freezer
Mouse Transgenic and Gene Targeting Facility	Gene Targeting	Service	Gene targeting services through transfection and microinjection of murine embryonic stem (ES) cells to produce germline knockout (KO) or knockin (KI) mice
Mouse Transgenic and Gene Targeting Facility	Incubator	NuAire CO2 water jacketed Incubators	Transgenics and gene targeting incubators (3 units)
Mouse Transgenic and Gene Targeting Facility	Microinjector	Eppendorf FemtoJet Microinjection System	Transgenics and gene targeting pronuclear injection system
Mouse Transgenic and Gene Targeting Facility	Micromanipulator	Eppendorf Transferman NK 2 Micromanipulators	Transgenics and gene targeting micromanipulators (2 units)
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon Eclipse TE200 Inverted Microscope	Transgenics and gene targeting microinjection microscope
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon Eclipse TS100 (cell culture scope)	Transgenics and gene targeting cell culture scope
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon SMZ1500 Zoom Stereomicroscopes	Transgenics and gene targeting dissecting microscopes (2 units)
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon SMZ800 Zoom Stereomicroscopes	Transgenics and gene targeting surgical microscope
Mouse Transgenic and Gene Targeting Facility	Technical Assistance - Karyotyping	Service	Service to determine euploidy of murine embryonic stem (ES) cells prior to microinjection
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - CRISPR Design and Reagent Preparation	Service	Service to provide consultation, design a CRISPR model, synthesize sgRNAs and prepare microinjection mix
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - CRISPR Donor Construction	Service	Service to construct a donor DNA for a CRISPR model
Mouse Transgenic and Gene Targeting Facility	Technical Assistance -Transgenics and Gene Targeting	Service	Service to provide custom services related to microinjection, ES cell culture, mouse surgery, or mouse reproduction. The core facility will provide services and/or training related to our capabilities that are not specifically covered by our service list. These services are available for an hourly fee. Examples include: production of MEFs (murine embryonic fibroblasts), polar body biopsy, reproductive surgery, blastomere injection, frozen embryo shipment, training
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Cryopreserved Mouse Embryo Recovery	Service	Service to thaw and implant previously cryopreserved mouse embryos
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Cryopreserved Mouse Embryo Storage	Service	Service to store cryopreserved mouse embryos in liquid nitrogen (LN2)
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Derivation of Mouse Embryonic Stem (ES) cell lines	Service	Service to produce embryonic stem (ES) cells from an existing mouse line key words: murine embryonic stem cells
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Embryonic Stem (ES) Cell Injection	Service	Service to produce chimeric mice for analysis through microinjection of murine embryonic stem (ES) cells into blastocyst stage embryos.
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mouse Colony Expansion	Service	Service to use superovulation and surgical implantation to produce large cohorts of age matched mice for experimentation or to quickly expand a mouse colony
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mouse Embryo Cryopreservation	Service	Service to cryopreserve valuable mouse lines for storage or shipment to other investigators.
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mouse In vitro Fertilization (IVF)	Service	Service to perform in vitro fertilization of mouse embryos
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Rederivation of Mouse Lines	Service	Service to rederive mouse lines obtained from a source other than a Brown University approved vendor. Rederived mouse lines may be housed in any campus mouse facility.
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Transgenic Production	Service	Service to perform pronuclear microinjection of 0.5 dpc mouse embryos to produce transgenic or CRISPR founders on an FVB/N or C57/BL6 background. Custom backgrounds also available.
Mouse Transgenic and Gene Targeting Facility	Water Purification System	Milli Q Biocel	Transgenics and gene targeting water purification
Mouse Transgenic and Gene Targeting Facility	Waterbath	Thermo Scientific Precision 260 Circulating Waterbath	Transgenics and gene targeting circulating waterbath
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - CRISPR Genotyping	Service	Service to genotype founders and G1 progeny from a CRISPR project
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - CRISPR Founder TA cloning & Sequencing	Service	Service to subclone and sequence a PCR amplicon from founders of a CRISPR project
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mating for Germline Transmission	Service	Service to breed chimera from mouse ES cell injection or founders from a CRISPR project with WT mice for germline transmission
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Sperm Cryopreservation	Service	Service to cryopreserve sperm from males provided by investigators
Multiplex Facility	Behavioral Phenotyping - Four Lane Rotarod	Emitter-Columbus Rotamex 5 Controller	Used to assess motor coordination and balance
Multiplex Facility	Behavioral Phenotyping - Morris Water Maze	Fabricated in house	Opaque white pool with platform for behavioral swim test.
Multiplex Facility	Biospecimen Banking - Freezer	HHP Barcoding Instrument	Barcode samples for identification. File Pro software.
Multiplex Facility	Centrifuge	Beckman- Coulter Allegra 64R Refrigerated Centrifuge	For use with 50 mL conical tubes.
Multiplex Facility	Cryostat	Leica Cryostat	Frozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.
Multiplex Facility	Disrupter	Siegen Tissue Lyser	Disrupts multiple biological samples through high speed shaking in plastic tubes with steel, tungsten carbide, or glass beads. Up to 48 samples can be processed simultaneously.
Multiplex Facility	Imaging System	Applied Scientific Instrumentation MS-1000	XY stage designed to provide a high resolution, and highly repeatable, means of controlling the X and Y position of a microscope stage
Multiplex Facility	Imaging System - Camera	Olympus U-CMAD3 camera	Connected to Olympus Inverted CKX31 Fluorescent Microscope. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Multiplex Facility	Imaging System - Camera	Sony 3CCD Exwave HAD Digital Camera	Connected to Olympus BX60. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Multiplex Facility	Imaging System - Camera	Stereologer 200	1/3" type DSP 3-CCD PAL color video camera with improved camera sensitivity (F8 at 2000 lx). Resolution of 800 TVL and a high S/N ratio of 61 dB.
Multiplex Facility	Microplate Reader	Molecular Dynamics M5 Spectracount	Cross talk (96-well): 3X 10-5, sensitivity: <20 attomol ATP per well, <0.2 firely luciferase per well, spectral range: 380-630 nm.
Multiplex Facility	Microplate Reader	Packard-Perkin Elmer Topcount	Analysis of cell proliferation, receptor binding assays, solid phase RIA/LIA, reporter gene assays, 51Cr release assays, HPLC fraction analysis, scintillation proximity assays, etc.
Multiplex Facility	Microplate Reader	Molecular Devices UV Max Microplate Reader	96-wellplate reader. Spectral range: 405-630 nm.
Multiplex Facility	Microscope	Olympus BX60	High-resolution digital pictures using conventional manual filter cubes or more versatile automated filter wheels, and can superimpose multi-color pictures
Multiplex Facility	Microscope	Olympus Inverted CKX31 Fluorescent Microscope	Inverted microscope with the capability of a fluorescence illuminator for GFP; documentation of images with digital imaging and video monitoring. Use for petri dishes, culture flasks, and multi-well plates.
Multiplex Facility	Microscope	Olympus Inverted Fluorescent microscope	FN22. 9mm stroke, coaxial coarse and fine focusing knobs. Long working distance universal condenser.
Multiplex Facility	PCR Thermal Cycler	Roche Lightcycler 4810	Exchangeable 96 or 384 multiwell plate format. Ideal for multiplexing and automated workflows. Provides various methods for gene detection, gene expression analysis, genetic variation analysis and array data validation.
Multiplex Facility	Robotic Workstation - DNA Extraction	QUIAGEN Biorobot EZ1	Fully automated purification of genomic DNA from human whole blood and viral nucleic acids from serum or plasma samples.
Multiplex Facility	Robotic Workstation - Pipetting	Eppendorf EpMotion 5070	Automated pipetting. Four deck positions can hold tips, reagent reservoirs, single tubes, tube racks, micro-plates, or PCR plates with up to 384 wells. Suited for serial dilutions, reagent distribution, transfer from tubes to plates and normalization.
Multiplex Facility	Robotic Workstation - Pipetting	Tecan Genesis 200 Robot	Automated robot for pipetting tasks. Two arms- the LiHa (liquid handler) and the RoMa (robot manipulator). LiHa- conductivity-sensing 8-channel pipetting arm dispenses volumes of 5-1000 �L; RoMa- manipulating arm picks up and moves objects on the workstation.
Multiplex Facility	Spectrophotometer	Thermo Scientific NanoDrop 2000	Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter.
Multiplex Facility	Suspension Array	Luminex Magpix	Reads magnetic bead�based immunoassays. Automated reading of 96-well plates (~60 min/plate). Multiplex analysis of up to 50 biomolecules in a single sample.
Multiplex Facility	Suspension Array	Bio-Rad BioPlex 100	Automated reading of 96-well plates, up to 9,600 data points in about 35 min. Multiplex analysis of up to 100 biomolecules in a single sample via suspension array.
Multiplex Facility	Suspension Array System	Bio-Rad Vacuum manifold	Vacuum purification platform for single 96-well plates or individual luer-ended spin columns. Compatible with Bio-Plex 200 suspension array system.
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 300 Avance	z-BBI probe, (least sensitivte 1H and indirect detection to all broadband nuclei)
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 600 Avance III HD Ascend	z-BBFO probe for all nuclei (most sensitive for all nuclei)
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 400 Avance III Ultra-Shield	z-BBFO (2nd most sensitive for 1H and broadband nuclei)
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 400 Avance Ultra-Shield	z-BBO (3rd best sensitivity for broadband nuclei)
PC - Albertus Magnus Hall Labs	Environmental Chamber Contact: Maia Bailey	Percival Scientific	1 unit
PC - Albertus Magnus Hall Labs	Environmental Chamber Contact: Maia Bailey	Percival Scientific, AR-22L Growth Chamber	For Arabidopsis
PC - Albertus Magnus Hall Labs	Imaging - Camera Contact: Pat Ewanchuk	Fastec HiSpec1, Low-Light High-Speed Camera	Innovative Low-Light High-Speed Camera. Monochrome with 2GB Memory, C-Mount, includes ImageBLITZ Auto Trigger, Burst Trigger Mode, Multi- Sequence Record Mode (1280 x 1024 at 506fps) 2 Units
PC - Albertus Magnus Hall Labs	Microscope - Electron Contact: Joe DeGiorgis	Philips EM-300 Transmission Electron Microscope (TEM)	Transmission electron microscopy
PC - Albertus Magnus Hall Labs	Laboratory - Prep Lab Contact: Joe DeGiorgis	Electron Microscopy Prep Lab	Laboratory space for preparing samples for electron microscopy
PC - Albertus Magnus Hall Labs	Microscope - Electron Contact: Joe DeGiorgis	Amray-1000 Scanning Electron Microscope (SEM)	Scanning Electron Microscope equipped with EDEX for elemental analysis and a digital imaging system, a Zeiss Axiophot equipped for bright field, dark field, DIC and fluorescence microscopy with a digital imaging system
PC - Albertus Magnus Hall Labs	Microtome Contact: Joe DeGiorgis	Porter-Blum MT-2B Ultramicrotome	Porter-Blum MT-2B UltraMicrotomes, 2 Units
PC - Albertus Magnus Hall Labs	Aquatic System Contact: Pat Ewanchuk	Aquatic Habitats Glass Tank System and Life Support Controller	Glass tank system and life support controller with low water level protection (18-10 gallon tanks)
PC - Albertus Magnus Hall Labs	Visualization- Camera lucida Contact: James Waters	Drawing tube, for MZ and M� series, the object and the drawing surface are visible at the same time, suitable for drawing for left and right �handed persons, work is possible in the daylight, documents can be mirrored� in	Leica
PC - Albertus Magnus Hall Labs	Respiratory physiology- Li-7000 CO2/H2O Analyzer Contact: James Waters	The LI-7000 is a high performance, dual cell, differential gas analyzer. It uses a dichroic beam splitter and two separate detectors to measure infrared absorption by CO2 and H2O in the same gas stream. The LI-7000 is ideally suited for applications that demand high speed, high precision measurements in absolute and/or differential modes, including plant and insect gas exchange using chamber-based methods, atmospheric-surface flux eddy covariance and Bowen ratio techniques, vertical profiling, and general atmospheric monitoring.?	LI-COR Biosciences
PC - Hickey Hall Labs	DNA Sequencer Contact: Elisabeth Arevalo	ABI Prism 3100 Genetic Analyzer	Used for DNA sequencing and fragment analysis. The ABI PRISM 3100 Genetic Analyzer is an automated capillary electrophoresis system that can separate, detect, and analyze up to 16 capillaries of fluorescently labeled DNA fragments in one run.
PC - Hickey Hall Labs	PCR Thermal Cycler Contact: Charles Toth	Stratagene Mx3000p Real-time PCR Thermal Cycler	This instrument is available for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Agilent�s qPCR software, MxPro, provides users with an intuitive interface, quick experiment design, powerful data analysis and easy report generation
PC - Hickey Hall Labs	Fluorescence Activated Cell Sorter (FACS) Contact: Charles Toth	Flow Cytometer- Accuri C6	The BD Accuri C6 is a personal flow cytometer that is easy to use, simple to maintain, and affordable.
PC - Hickey Hall Labs	Cold Room Contact: Charles Toth	Walk-In Cold Room
PC - Hickey Hall Labs	Analyzer - Cell Metabolism Contact: Marla Tipping	Seahorse Biosciencies, XFe Extracellular Flux Analyzers, XFe96	Platform for metabolic assays that simultaneously measures the two major energy producing pathways of the cell - mitochondrial respiration and glycolysis - in a microplate, in real-time.
PC - Hickey Hall Labs	Laboratory - Tissue Culture Contact: Charles Toth	Tissue Culture Laboratory	Space and instrumentation for tissue culture preparation
PC - Hickey Hall Labs	Imaging System - Gel Imager Contact: Yinsheng Wan	Licor Odyssey IR (Infrared) Imaging System	Instrumentation for quantitating western blots.
PC - Hickey Hall Labs	Fluorescence Activated Cell Sorter (FACS) Contact: Nicanor Austriaco	Cellometer Vision Image Cytometry	The Vision CBA System combines the simplicity of image cytometry with the power of flow analysis software to offer user-friendly cell-based assays
PC - Hickey Hall Labs	Spectrophotometer Contact: Charles Toth	Thermo Scientific NanoDrop	UV/VIS
PC - Sowa Hall Labs	Microscope Contact: Joe DeGiorgis	Zeiss LMS 700 Flexible Confocal Microscope	Performs fluorescence measurements, creates optical sections of samples and combines them into 3D image stacks.
Plant Environmental Center	Greenhouse, Plant Environmental Center Contact: Chris Claussen	Plant environmental center with seven separate, computer controlled rooms where conditions like lighting, temperature, and humidity can be fine tuned; an additional 17 controlled plant growth environments provided by growth chambers (15) and walk-in growth rooms (2)	A plant environmental center with a suite of supporting facilities, including a classroom, a "headhouse" for potting and other prep work,and growth chambers for plants.
Proteomics Facility	Bioinformatics Analysis - Mascot Server	Software: Matrix Science Mascot Search Engine	Software for protein identification, characterization and quantitation (v.2.5)
Proteomics Facility	Bioinformatics Analysis - PEAKS Studio	Software: Bioinformatics Solutions Inc. PEAKS Studio	Software for de novo sequencing and database searching (v.7.0)
Proteomics Facility	Bioinformatics Analysis - ProSight PC Contact: Mandar T Naik	Software: Thermo Scientific ProSight PC	Software for Top-Down proteomics analysis (v.2.0)
Proteomics Facility	Bioinformatics Analysis - ProteoIQ	Software: NuSep ProteoIQ Mass Spec Data Analysis	Software for mass spectrometry proteomic analysis (v.2.7)
Proteomics Facility	Bioinformatics Analysis - Proteome Discoverer	Software: Thermo Scientific Proteome Discoverer	Software for database searching and protein quantitation (v.1.4)
Proteomics Facility	Calorimeter	Microcal Isothermal Titration 200 (ITC)	Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
Proteomics Facility	Calorimeter	Microcal VP Differential Scanning (DSC)	Measurement of heat changes that occur in biomolecules during controlled increase or decrease in temperature.
Proteomics Facility	Fermenter	Infors Minifor	A bench-top (1-5 L) laboratory fermenter and bioreactor for bacteria and yeast.
Proteomics Facility	Fluorometer - Spectrofluorometer	Horiba Jobin Yvon FluoroMax-4	Fluorescence detection. A heated cell allows temperature studies.
Proteomics Facility	High Performance Liquid Chromatography (HPLC)	Agilent 1200 HPLC System	High performance liquid chromatography system with: quaternary pump, thermostatted autosampler, thermostatted fraction collector, and a multi-wavelength UV/Vis detector. It can be used for analytical detection of biomolecules and/or their purification.
Proteomics Facility	Liquid Chromatography System	GE Healthcare AktaPrime Plus	The KTA Prime Plus is a low pressure chromatography system that performs simple purifications of tagged and untagged proteins.
Proteomics Facility	Spectrophotometer	JASCO J-815 Circular Dichroism (CD) Spectrometer	Protein folding studies, Protein conformational studies, DNA/RNA interactions, Enzyme kinetics, Purity testing of optically active substances, quantitative analysis of pharmaceuticals, natural products chemistry, biochemistry and macromolecules, rapid scanning (time resolved) experiments. Peltier device for temperature studies.
Proteomics Facility	Spectrometer	Thermo Scientific NanoDrop 8000	A full spectral microvolume (microliter) UV-Vis analysis spectrophotometer for measuring DNA, RNA, and protein of 8 samples simultaneously.
Proteomics Facility	Surface Plasmon Resonance (SPR) Sensor	GE Healthcare Biosciencees Biacore X 100	Label-free protein interaction analysis provides unique and comprehensive data on the interactions between biomolecules. Performs quantitative kinetic analysis (rate constants), quantitative determination of affinity constants, determination of binding specificity (yes/no), and concentration analysis.
Proteomics Facility	Technical Assistance - Proteomics Project Consultation	Service	Service to provide Proteomics Technical Assistance
Proteomics Facility	Technical Assistance - Proteomics Training	Service	Service to provide Proteomics Training
Proteomics Facility	Bioinformatics Analysis - Mascot Distiller	Software for peptide and protein quantitation (v.2.5.1)	Software: Matrix Science Mascot Distiller
Proteomics Facility	Bioinformatics Analysis - Scaffold	Software for mass spectrometry proteomic analysis (v.4.3.4)	Software: Proteome Software Scaffold Q+S
Proteomics Laboratory	Bioanalyzer Contact: Nagib Ahsan, PhD	Agilent Bioanalyzer 2100	Microfluidics platform (electrophoresis and flow cytometry) for sizing, quantification, and QC of DNA, RNA, proteins, and cells. Sample size= 1-4 microliters.
Proteomics Laboratory	Bioinformatics Analysis - MASCOT Contact: Nagib Ahsan, PhD	Software: Matrix Science MASCOT Search Engine	Software for MS data analysis through statistical evaluation of matches between observed and projected peptide fragments.
Proteomics Laboratory	Bioinformatics Analysis - ProteoIQ Contact: Nagib Ahsan, PhD	Software: NuSep ProteoIQ Mass Spec Data Analysis	Software for post-analysis of MASCOT results. Protein and peptide probabilities generated and protein relative quantitation is performed by spectral counting. Normalized and with standard deviations.
Proteomics Laboratory	Bioinformatics Analysis - Workstation Contact: Nagib Ahsan, PhD	Hardware: HP HPZ 800 Workstation	Software (2 workstations available) used in conjunction with ProteoIQ, DXMS, MASCOT analysis.
Proteomics Laboratory	Gel Imager Contact: Nagib Ahsan, PhD	Bio-Rad Molecular Imager VersaDoc	Quantitative digital imaging system for single or multi-color images. Includes multiplexed samples (1-D or 2-D gels), chemiluminescent and chemifluorescent blots, and microplates.
Proteomics Laboratory	High Performance Liquid Chromatography (HPLC) Contact: Nagib Ahsan, PhD	Bio-Rad DuoFlow Biologic HPLC	Medium-pressure chromatography system. 100/120 V, F10 workstation, mixer, AVR7-3 valve, UV detector with flow cell and filters. Flow rate= 0.01-10 ml/min.
Proteomics Laboratory	High Performance Liquid Chromatography (HPLC) Contact: Nagib Ahsan, PhD	Transgenomic Wave DHPLC System	Detect mutations/ polymorphisms by Denaturing High Performance Liquid Chromatography (DHPLC). Uses SURVEYOR nuclease cleavage. Identifies single nucleotide polymorphisms (SNPs) or small insertions/ deletions.
Proteomics Laboratory	High Performance Liquid Chromatography (HPLC) Contact: Nagib Ahsan, PhD	Dionex UltiMate3000 Nano HPLC	Single gradient and x2 dual configurations. Eluted directly into MS. Min detection= fmole; Min flow rate= 20 nL/min; Max pressure = 800 bar.
Proteomics Laboratory	Liquid Chromatography- Mass Spectrometer (LC-MS) Contact: Nagib Ahsan, PhD	Thermo Scientific Q Exactive Plus Mass Spectrometer	Benchtop LC-MS/MS. Combination of high-performance quadrupole with high resolution, accurate-mass (HR/AM) Orbitrap. Max resolving power= 140,000; max scan speed= 12Hz, Intra-scan dynamic range > 5000:, Quadrupole mass filter.
Proteomics Laboratory	Mass Spectrometer Contact: Nagib Ahsan, PhD	AB SCIEX QSTAR XL Mass Spectrometer	Identification and analysis of protein structure/conformational change by deuterium exchange mass spectrometry (DXMS). LC/MS/MS- Ionization by MALDI or ESI after HPLC (Dionex) and analyzed by quadrupole and TOF.
Proteomics Laboratory	Mass Spectrometer Contact: Nagib Ahsan, PhD	Brucker UltrafleXtreme: Imaging Mass Spectrometry	MALDI-IMS for tissue imaging, intact proteins analysis, protein spatial distribution, glycoproteomics, or biologics (1-2000 Hz repetition rates) of non-injured vs. injured tissues. MALDI/TOF/TOF analysis for proteomic profiling. Minimum diameter = 10 microns.
Proteomics Laboratory	Robotic Workstation -Liquid Handler Contact: Nagib Ahsan, PhD	Perkin Elmer JANUS Automated Workstation	Automated Sterile Liquid Handler. 2 arm system, with 4- or 8-tip arm plus a 96/384 MDT arm. Arms include 4-tip or 8-tip dispense arms for transfer from tubes to vials to plates.
Proteomics Laboratory	Spectrophotometer Contact: Nagib Ahsan, PhD	Amersham Biosciences UV/Visible Spectrophotometer Ultrospec 1100	Wavelength range: 200-900 nm. Spectral bandwidth: 5 nm Wavelength accuracy - 2 nm. Wavelength reproducibility: - 0.5 nm.
Proteomics Laboratory	Spectrophotometer Contact: Nagib Ahsan, PhD	Thermo Scientific NanoDrop 2000	Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter.
Proteomics Laboratory	Suspension Array System Contact: Nagib Ahsan, PhD	Bruker ImagePrep matrix sprayer	Matrix deposition device for MALDI Imaging. Average droplet size ? 20 microns, all droplet dia. are < 50 microns. Lateral resolution of 50 microns in tissue.
Proteomics Laboratory	Technical Assistance - 1D SDS PAGE Coomasie Contact: Nagib Ahsan, PhD	Service	Service to provide 1D gel (SDS-PAGE) Coomasie Staining.
Proteomics Laboratory	Technical Assistance - 1D SDS PAGE Silver Stain Contact: Nagib Ahsan, PhD	Service	Service to provide 1D gel (SDS-PAGE) Silver Stain MS compatible.
Proteomics Laboratory	Technical Assistance - Gel Imaging Contact: Nagib Ahsan, PhD	Service	Service to provide Gel imaging by VersaDoc.
Proteomics Laboratory	Technical Assistance - Mass Spectrometry Contact: Nagib Ahsan, PhD	Service	Service to provide ImagingMass Spectrometry Data Analysis.
Proteomics Laboratory	Technical Assistance - Protein Determination Contact: Nagib Ahsan, PhD	Service	Service to provide Protein Determination (BCA assay).
Proteomics Laboratory	Technical Assistance - Protein Extraction Contact: Nagib Ahsan, PhD	Service	Service to provide ReadyPrep Protein Extraction Kit (Sequential Extraction).
Proteomics Laboratory	Technical Assistance - Protein Extraction Contact: Nagib Ahsan, PhD	Service	Service to provide ReadyPrep Protein Extraction Kit (Total Protein).
Proteomics Laboratory	Technical Assistance - Protein In-Gel Digestion Contact: Nagib Ahsan, PhD	Service	Service to provide In-gel digestion LC/MS analysis and protein database search.
Proteomics Laboratory	Technical Assistance - Protein In-Solution Digestion Contact: Nagib Ahsan, PhD	Service	Service to provide In-solution digestion LC/MS analysis and protein database search.
Proteomics Laboratory	Technical Assistance - Protein Quantification Contact: Nagib Ahsan, PhD	Service	Service to provide Data interpretation and protein quantification.
Proteomics Laboratory	Technical Assistance - Protein Sample Clean-up Contact: Nagib Ahsan, PhD	Service	Service to provide ReadyPrep 2D Cleanup Kit.
Proteomics Laboratory	Technical Assistance - Proteomics Project Consultation Contact: Nagib Ahsan, PhD	Service	Service to provide Project consultation with the Director of Proteomics - Subsequent Consultation
Proteomics Laboratory	Technical Assistance - Proteomics Project Consultation Contact: Nagib Ahsan, PhD	Service	Service to provide Project consultation with the Director of Proteomics - Initial Consultation
Research Facility	Autoclave	Tuttnauer	Equipment: consumable sterilization
Research Facility	Behavioral Phenotyping - Eye Tracking System	Tobii	Used to track eye movement
Research Facility	Bioanalyzer	Agilent Bioanalyzer	DNA size & quantification (quality check for downstream analyses, i.e. next gen sequencing)
Research Facility	Capillary Electrophoresis	Applied Biosystems 3500	Analyze fragment length polymorphisms (96 format) (2)
Research Facility	Centrifuge	Eppendorf Refrigerated Centrifuge	Alcohol precipitation
Research Facility	Centrifuge	Eppendorf	For centrifuging 96/384 plates
Research Facility	DNA Sequencer	Ion Torrent/Life Technologies Personal Genome Machine	Next Generation Sequencer
Research Facility	Mass Spectrometer	Sequenom	high throughput SNP genotyping, epigenetics
Research Facility	Microarray Scanner	Illumina HiScan	Whole-genome genotyping, gene expression analysis, methylation analysis
Research Facility	Microplate Reader	BioTek	DNA quantification
Research Facility	Microplate Reader	Fluidigm End Point Reader	High throughput SNP genotyping
Research Facility	PCR Thermal Cycler	Applied Biosystems	384 well DNA amplification for downstream analysis (i.e. sequenom processes) (2 units)
Research Facility	PCR Thermal Cycler	Applied Biosystems	96 well DNA amplification for downstream analysis (i.e. fragment length polymorphisms)(2 units)
Research Facility	PCR Thermal Cycler	Applied Biosystems Real Time PCR	Analyze single nucleotide polymorphisms (single locus)
Research Facility	PCR Thermal Cycler	Applied Biosystems Real Time PCR	Analyze single nucleotide polymorphisms (single locus)
Research Facility	Robotic Workstation - DNA Extraction	Chemagen/Perkin Elmer Magnetic Separation Module	DNA extraction from blood & saliva
Research Facility	Robotic Workstation - Liquid Handler	Sequenom Liquid Handler	Transfers PCR chemistries to samples (96/384 format)
Research Facility	Robotic Workstation - Liquid Handler	Sequenom Nanodispenser	Dispenses PCR product to Sequenom chip
Research Facility	Robotic Workstation - Sample Preparation	Iontorrent/Life Technologies Enrichment System	Simplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.
Research Facility	Robotic Workstation - Sample Preparation	Iontorrent/Life Technologies One Touch	Simplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.
Research Facility	Robotic Workstation - Sample Processing	Thermo Scientific Cap-it-All	Caps tubes to the optimal torque to maintain sample integrity and provide a hands free method to capping and decapping tubes quickly and easily.
Research Facility	Robotic Workstation -Liquid Handler	Beckman Coulter Lab Automation Workstation	Automated liquid handler
Research Facility	Spectrophotometer	Thermo Scientific NanoDrop	DNA quantification
Research Facility	DNA Sequencer Contact: Kayla Dwyer	Qiagen Pyromark Q96 ID	Quantitative analysis of genetic/epigenetic DNA modifications using Pyrosequencing technology
Research Facility	Quant Studio 12K Flex PCR Thermal Cycler	Analyze single nucleotide polymorphisms (single locus) (96/384 format)	Applied Biosystems Real Time PCR
Research Facility	Robotic Workstation-Sample Preparation	Simplifies the workflows for the Illumina HiScan system by providing an automated solution for scalable and reproducible sample preparation.	Tecan Freedom Evo
Rhode Island BioBank	Bioinformatics Analysis - Freezerworks	Software: Freezerworks version 2015Ascent	Sample management software
Rhode Island BioBank	Biospecimen Banking	Service	Service to store biospecimens at -80 degrees, 4 degrees and in liquid nitrogen. All equipment is connected to back-up generator power and monitored 24/7 by a Rees alarm system.
Rhode Island BioBank	2 Biospecimen Banking - Freezer System2	Taylor Wharton LABS 40K Liquid Nitrogen Storage System	Liquid nitrogen biospecimen storage system. Holds up to 40,000 1ml samples
Rhode Island BioBank	3 Biospecimen Banking - Freezer Systems	Biospecimen Storage at -80 degrees. Holds up to 50,000 1ml samples	Thermo Scientific HERAfreezer 24 cu. Ft. -80 degree freezer
Rhode Island BioBank	3 Biospecimen Banking- Refrigerators	Biospecimen Storage at 4 degrees.	LABREPCO FUTURA Platinum Series 52 cu. ft. 4 degree hinged glass door refrigerator
Rhode Island BioBank	Robotic Workstation - Sample Preparation	Qiagen QiaCube	DNA, RNA or Protein Purification
Rhode Island Nuclear Science Center	Reactor, Research and Test Contact: Cameron Goodwin	2 Mega-Watt, light water cooled, pool type reactor	Neutron and gamma irradiation and experimental set-up, as well as analysis
RIC - Fogarty Life Sciences Labs	Knifemaker Contact: Breea Govenar	LKB 7800 Knifemaker	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Microtome Contact: Breea Govenar	Leica RM2165 Motorized Rotary Microtome	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Microtome Contact: Breea Govenar	TBS Microtome plus Cryostat	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	American Optical Series 10 Fluorescence Microstart	Microscopy course
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Nikon E600 Epifluorescence with DIC/Phase and digital camera	Research
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus CKS41 Inverted Microscope	Tissue culture general use
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus Compound Light Microscope	General use
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus FluoView 1000 Laser Scanning Confocal Microscope	Research and Microscopy course
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus Inverted Epifluorescence Microscope with digital camera	Tissue culture/Research
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Zeiss SteREO discovery V8 Microscope with Digital Camera	Research
RIC - Fogarty Life Sciences Labs	Wet Lab / Aquarium room Contact: Breea Govenar	Aquaria and related equipment	Research
RIC - Fogarty Life Sciences Labs	Autoclave Contact: Breea Govenar	Autoclave	Microbiology/Research
RIC - Fogarty Life Sciences Labs	Biological Safety Cabinet Contact: Breea Govenar	Labconco class II Biological Safety Cabinet	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Biological Safety Cabinet Contact: Breea Govenar	Sterile laminar flow hood	Microbiology prep
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Eppendorf 5810R Refrigerated Centrifuge	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Sorvall Discovery M120SE Mini Ultracentrifuge	Research/Cell fractionation
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Sorvall Superspeed RC2 Centrifuge	General use
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Sorvall Superspeed RC5 Plus Centrifuge	Research
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Thermo IEC Centra CL3R Refrigerated Centrifuge	Genetics and Cell & Molec courses
RIC - Fogarty Life Sciences Labs	Cold Room Contact: Breea Govenar	Walk-In Cold Room	Large cold room for experimentation and storage
RIC - Fogarty Life Sciences Labs	Dishwasher Contact: Breea Govenar	Dishwasher	Microbiology/Research
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	French Pressure Cell Press	Research
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	Polytron Tissue Grinder	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	Sonicator	General use and research
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	Sonicator with cup	Research and graduate courses
RIC - Fogarty Life Sciences Labs	Electroporation System Contact: Breea Govenar	BioRad Micropulser Electroporator	Research
RIC - Fogarty Life Sciences Labs	Freeze Dryer Contact: Breea Govenar	ATMO VAC 5009 freeze dryer	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Freezer Contact: Breea Govenar	Thermolyne Liquid Nitrogen cryogenic storage system	Cell storage
RIC - Fogarty Life Sciences Labs	Freezer Contact: Breea Govenar	Ultralow Freezer	Used for freezing biological samples, 6 units
RIC - Fogarty Life Sciences Labs	Gel Imager Contact: Breea Govenar	InGenius Syngene Gel Documentation System	Research
RIC - Fogarty Life Sciences Labs	Ice Machine Contact: Breea Govenar	Ice Machine	General use
RIC - Fogarty Life Sciences Labs	Imaging System - Dark Room Contact: Breea Govenar	Imaging System - Dark Room	Gel imaging and analysis
RIC - Fogarty Life Sciences Labs	Incubator Contact: Breea Govenar	Non CO2 Incubator	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Incubator Contact: Breea Govenar	Thermo CO2 Incubators	Used for tissue culture, 2 units
RIC - Fogarty Life Sciences Labs	Incubator Contact: Breea Govenar	Refrigerated Incubator	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Laboratory - Tissue Culture Contact: Breea Govenar	Tissue Culture Room	A room outfitted with tissue culture instrumentation
RIC - Fogarty Life Sciences Labs	Microplate Reader Contact: Breea Govenar	Lenovo Automated Plate Reader	Research
RIC - Fogarty Life Sciences Labs	Microplate Reader Contact: Breea Govenar	Thermo Labsystems Multiskan MMCC/340 plate reader	Research
RIC - Fogarty Life Sciences Labs	Oven Contact: Breea Govenar	Drying Oven	General use
RIC - Fogarty Life Sciences Labs	PCR Thermal Cycler Contact: Breea Govenar	BioRad IQS Real time PCR thermocycler	Research
RIC - Fogarty Life Sciences Labs	PCR Thermal Cycler Contact: Breea Govenar	Eppendorf Gradient Mastercycler	PCR instrumentation, 2 units
RIC - Fogarty Life Sciences Labs	Shakers Contact: Breea Govenar	Incubator/Shakers	Multiple units
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	BioRad SmartSpec Plus	Research
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Eppendorf Biophotometer	Gectrophotometerseral use
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Spectronic 21 D UV/VIS	Research
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Therm Spectronic Genesys UV/VIS Scanning	Research, 6 units
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Thermo Scientific NanoDrop ND-1000	UV/VIS, 2 units
RIC - Fogarty Life Sciences Labs	Water Purification System Contact: Breea Govenar	Barnstead Still Water Purifier	General use for teaching labs
RIC - Fogarty Life Sciences Labs	Water Purification System Contact: Breea Govenar	Millipore DirectQ (X2)	Tissue culture
RIC - Fogarty Life Sciences Labs	Water Purification System Contact: Breea Govenar	Millipore NanoPure Diamond	2nd floor research use
RIC - Fogarty Life Sciences Labs	Imaging System - X-ray Film Contact: Breea Govenar	X-ray film processor	Blot imaging
RISD Media Resources	Imaging System - Audio\|Visual	Kodak zi 10 Video Camera (8 units)	Portable HD pocket camcorder, batteries, adaptor cables, cases, accessories
RISD Media Resources	Imaging System - Audio\|Visual	H4N ZOOM Audio Recorder (5 Units)	High performance portable digital audio recorder, batteries, adaptor cables, cases, accessories
RISD Media Resources	Imaging System - Audio\|Visual	ZOOM Q3 Video Camera (7 Units)	Portable palm camcorder, batteries, adaptor cables, cases, accessories
RISD Media Resources	Imaging System - Audio\|Visual	EPS-SonyPMWEX1R-01 (2 Units)	High performance HD CMOS solid state video camera, batteries, portable hard drive, adaptor cables, cases, studio lighting equipment, accessories
RISD Nature Lab	Aquatic System	Marine Ecological Habitats Closed-System Aquarium	560 L closed-system recirculating marine holding tanks with temperature control (2 units)
RISD Nature Lab	Microscope	Phenom G2Pro Scanning Electron Microscope (SEM)	Desktop Scanning Electron Microscope with ProSuite tiling and remote access software
RISD Nature Lab	Microscope	Olympus SZX16 Stereomicroscope	Light microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging software
RISD Nature Lab	Microscope	Olympus IX51 Inverted Fluorescent/Brightfield Microscope	Fluorescence/brightfield microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging software
RISD Nature Lab	Microscope	Olympus CH30 Upright Light Microscope	Upright light microscope with 5 MP Jenoptik digital camera, Canon Vixia HFS20 HD video camera, computer workstation, graphics and imaging software (2 units)
RISD Nature Lab	Microscope	Olympus SZ40 Stereomicroscope	Light microscope with 5 MP Jenoptik digital camera, computer workstation, graphics and imaging software
RISD Nature Lab	Microscope	Olympus SZ30 Stereomicroscope	Light microscope with LED illuminator (24 units)
RISD Nature Lab	GPS Unit	Trimble Geo 7x Subfoot GPS	Survey-grade high resolution handheld GPS unit with sub-foot accuracy
RISD Nature Lab	GPS Unit	Garmin eTrex 30 (10 units)	Mapping grade gps unit for student use
RISD Nature Lab	Videocamera - High Speed	Edgertronic - monochrome	High speed videocamera for capturing slow motion footage. Capable of Resolutions up to 1280x1024, frame rates at lower resolution up to nearly 18,000 fps
RISD Nature Lab	Videocamera - High Speed	Edgertronic - color	High speed videocamera for capturing slow motion footage. Capable of Resolutions up to 1280x1024, frame rates at lower resolution up to nearly 18,000 fps
RISD Nature Lab	Videocamera - High Speed	Phantom Miro M120	Digital high speed video camera, resolution up to 1920x1080 at 800fps
RISD Nature Lab	Scanner, 3D	Artec Spider	High resolution 3D scanner designed specifically for CAD users
RISD Nature Lab	Scanner, 3D	Structure Sensor	Scanners (3) for use with iPad Air, capable of 3D scanning objects and entire rooms
RISD Nature Lab	Workstation, Computer Geographic Information System (GIS)	EPC workstations (3)	Computer workstations outfitted with ArcGIS, auto cad and the full adobe creative suite
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping	Service	A high-throughput behavioral testing facility that integrates high-level computer vision, computer learning, and custom built hardware solutions with behavioral testing to automate tracking, cataloging, and analysis of both home cage behavior and standard rodent testing paradigms to characterize preclinical models of disorders, test novel pharmacological and genetic rescue strategies in rodent models.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - 4x Operant Chambers	Med Associates	Can be used to train mice on operant tasks (equipped with water dipper system) for reinforcement learning, as well as grid floor and speaker system for fear conditioning experiments
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - 2x Open Field	Fabricated in house	Used to monitor activity in novel settings and to assay anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - 3-chamber Social Preference	Fabricated in house	Used to assess a mouse preference for being in close proximity to another mouse.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Barnes Maze	Fabricated in house	Used to assess spatial learning and memory in rodent models.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Cold Swim Stress	Fabricated in house	Used to monitor anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Cylinder Test	Fabricated in house	Used to assess motor coordination and balance
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Early Life Drug Exposure	Fabricated in house	Used to assess the impact of pharmacological agents on cognitive, motor, and affective development.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Early Life Stress (Maternal Bedding Restriction)	Fabricated in house	Used to induce later development of anxiety and depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Early Life Stress (Variable shock)	Fabricated in house	Used to assess elevated levels of anxiety and depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Elevated Zero Maze	Fabricated in house	Used to monitor rodent anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Estrous Cycling (Vaginal Cytology)	Fabricated in house	Used to assess stage of estrous cycle of rodent models.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Exercise Induced Anorexia	Fabricated in house	Use of running and food restriction to induce lower levels of body fat and food consumption
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Five Lane Forced Treadmill	Columbus Instruments	Used to induce exercise stress to assess motor fatigue and locomotor abilities.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Five Lane Rotarod	Med Associates	Used to assess motor pattern learning and coordination.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Flurothyl Induced Seizures	Fabricated in house	Used to assess monitored induction of tonic and clonic seizures
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Forced Swim	Fabricated in house	Used to assess depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Formalin Test (Pain)	Fabricated in house	Used to assess chronic pain
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Grip Strength Meter	Columbus Instruments	Used to assess grip strength
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Hargreaves Method to Assess Allodinia	IITC	Used to assess thermal sensitivity and efficacy of analgesics to decease pain sensitivity
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Homecage Monitoring	Fabricated in house	Used for long term monitoring of homecage activity of mice. Can provide longitudinal data regarding (eating, resting, grooming, drinking, walking, climbing, rearing, and micromovements). Will be used as a proxy for other more acute tests.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Homecage Wheel Running	Lafayette Instruments	Used to assess general levels of locomotor activity and as a proxy to measure changes in circadian rhythms.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Hot Plate Analgesia Meter	Basille	Used to assess thermal sensitivity.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Light /Dark Box	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Marble Burying	Fabricated in house	Used to assess anxiety-like behavior and OCD-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Maternal Deprivation	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Maternal Separation	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Morris Water Maze	Fabricated in house	Used to assess spatial learning and memory
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Non-invasive Blood Pressure Monitoring	Columbus Instruments	Tail cuff and apparatus for repeated measurement of blood pressure in mice.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novel Object Identity	Fabricated in house	Used to assess working memory
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novel Object Location	Fabricated in house	Used to assess spatial learning and memory
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novelty Induced Hypophagia	Fabricated in house	Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novelty Suppressed Feeding	Fabricated in house	Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Olfactory Cross-habituation	Fabricated in house	Used to assess olfactory acuity.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Olfactory Perceptual Learning	Fabricated in house	Used to assess ability to learn to discriminate closely related odor pairs.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Predator Odor Stress	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Resident Intruder Aggression	Fabricated in house	Used to assess propensity for aggressive behavior.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Restraint Stress	Fabricated in house	Used to assess hippocampal atrophy and increased anxiety and depressive-like behavior.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Righting Reflex	Fabricated in house	Used to assess coordination and ability to right from a prone position.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Shock Threshold	Fabricated in house	Used to assess changes in pain sensitivity
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Single Lane Rotarod	Med Associates	Used to assess motor pattern learning and coordination.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Social Defeat Stress	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Social Disruption Stress	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Social Odor Discrimination	Fabricated in house	Used to assess ability to detect and discriminate between odorants of conspecifics.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Sucrose Preference	Fabricated in house	Used to asses depressive-like behavior (anhedonia).
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Tail Suspension	Fabricated in house	Method to assess depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Visual Cliff	Fabricated in house	Used to assess depth perception and avoidance learning during visual development.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - von Frey Filaments	Bioseb	Used to assess tactile sensitivity
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Wire-hang	Fabricated in house	Used to assess animals strength and endurance.
RWU Lab Spaces	Flow Cytometer Contact: Marcie Marston	Millipore Guava easyCyte Flow Cytometer	Flow Cytometer
RWU Lab Spaces	Gas Chromatograph - Mass Spectrometer (GC - MS) Contact: Nancy Breen	Agilent 5890 Gas Chromatograph - Mass Spectrometer (GC - MS) wth Mass Selective Detetor (MSD)	GC MS for teaching and research
RWU Lab Spaces	High Performance Liquid Chromatography (HPLC) Contact: Nancy Breen	Waters 2695 High Performance Liquid Chromatograph-MS / ZQ Micromass Mass Spectrometer	LC - MS for teaching and research
RWU Lab Spaces	Gas Chromatograph Contact: Nancy Breen	Agilent 7890 Gas Chromatography with DB-23 column	GC for fatty acid analysis
Salve Regina Biology and Biomedical Sciences	Flow Cytometer	Millipore Guava EasyCyte 8 Flow Cytometer	Single blue (488 nm), dual blue and red (642 nm), or triple blue, red, and violet (405 nm) excitation lasers provide up to 12 simultaneous detection parameters, including 10 fluorescent colors plus forward and side scatter for size and granularity determination. The guava easyCyte family also meets your sample throughput needs by offering both single sample and multi-sample processing.
Statistical Consulting Unit (SCU)	Statistical Consulting	Service	The Statistical Consulting Unit (SCU) offers a variety of services. We operate a free clinic where each client will be offered a free one-hour initial consultation. The initial consultation is a face-to-face meeting between the client(s) and two SCU consultants. For some projects, this initial consultation will be the only assistance that is required. For others, the purpose of the free consultation will include assessing the project needs and the scope of work required, as well as estimating the project cost. For those projects usually require assistance in data analysis and manuscript preparation, we will provide these services for an agreed upon fee, as explained in the Rates link of this website. The SCU will act as a point-of-contact for investigators interested in establishing a collaborative relationship with Center for Statistical Sciences faculty, who will be serving as the co-PIs or co-investigators on grant proposals. The SCU will refer the investigators to faculty who are best suited to serve such roles.
Statistics and Data Management Core	Technical Assistance - Statistics and Data Management Contact: Sangshin Park, PhD	Service	This Core provides consultation and assistance in managing and analyzing research data, such as the large datasets, and in linking these data with clinical predictors and outcomes collected in the field. The Core also performs more sophisticated data analytic approaches, including hierarchical, repeated measures modeling and Principal Components Analysis.
Structural Biology Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 500 Avance II, with TCI cryoprobe	An NMR spectrometer optimized for studying proteins in solution. This spectrometer is most useful for tracking binding interactions, measuring dynamic properties of proteins, and assigning protein resonances. Capable of using 5 mm and 3 mm tubes. Also suitable for proton NMR of small molecules and natural products.
Structural Biology Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 850 MHz Avance III HD, with TCI cryoprobe	An NMR spectrometer optimized for studying proteins in solution. This spectrometer is ideal for determining protein structures and measuring protein dynamics. Its extreme sensitivity allows studies on otherwise intractable samples. Capable of using 5 mm, 3 mm, and shaped NMR tubes. Also suitable for proton NMR of small molecules and natural products
Structural Biology Facility	X-ray Diffraction System	Rigaku ACTOR robot and Saturn 944 HG CCD	An instrument useful for obtaining X-ray diffraction patterns of proteins and other biomacromolecules under cryogenic or room-temperature conditions. Rapid screening and sorting of up to 80 candidate crystals is possible.
Tissue Bank Core Facility (RWMU)	Specimen access	Service
Tissue Bank Core Facility (RWMU)	Tissue Banking	Service	Service
Tissue Banking Core	Bioinformatics Analysis - Database	Software: Database developed in Filemaker Pro	Database and tissue inventory management on a Dell computer workstation
Tissue Banking Core	Biospecimen Banking - Biosafety Cabinet	Dissecting hood	Hood dedicated to sterile tissue cutting with biohazard protection.
Tissue Banking Core	Biospecimen Banking - Freezer System	Forma 195878 LN2 backup for bank freezers	Systems inject liquid LN2 into cabinet when cabinet temperature warms to preset level, adjustable in 1 C increments to -150 C.
Tissue Banking Core	Biospecimen Banking - Freezing Bath	Low temp isopentane bath	Bath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.
Tissue Banking Core	Histology/Tissue Processing - Freezing Bath	Low temp isopentane bath	Bath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.
X-ray Reconstruction of Moving Morphology Facility (XROMM)	Computed Tomography (CT) Scanner	Animage Fidex Veterinary	Veterinary CT Scanner designed for animals in the size range from rats to dogs. In vivo scanning of anesthetized animals is possible.
X-ray Reconstruction of Moving Morphology Facility (XROMM)	Videoradiography Room	Custom made biplanar	3D x-ray motion analysis methods that combine skeletal movement data from in vivo x-ray videos with skeletal morphology from 3D bone scans (e.g. computed tomography (CT) or laser scans).
X-ray Reconstruction of Moving Morphology Facility (XROMM)	X-ray Fluoroscopes	Radiological Imaging Mobile C-Arm X-ray	Two retrofitted with 30-cm image intensifiers and high-speed video cameras for measuring accurate 3D skeletal kinematics of small to medium-sized animals.

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