Instrument/Service

Facility	Instrument/Services	Manufacturer/Description	Functions
Benedum Stable Isotope Facility	Mass Spectrometer, Isotope Ratio	ThermoFisher (Finnigan) MAT 252 dual inlet Isotope Ratio Mass Spectrometer with automated sample reaction device for up to 48 samples and with Kiel III Carbonate interface.	Instrument primarily dedicated to the measurement of the stable isotopes of carbon and oxygen on inorganic carbonates. The facility accommodates projects both internal and external to Brown including analysis of terrestrial and marine material. The vast majority of samples analyzed are funded through external grants but I also facilitate a significant number of small unfunded, exploratory, analyses to help construct proof-of-concept data sets in preparation for proposals.
Bioinformatics Core	Bioinformatics Analysis	Service	Service to provide bioinformatics consultation, education, and training
Bioinformatics Facility	Bioinformatics Analysis	Service	Service to provide technical assistance and training in bioinformatics
Bioinformatics Facility	Bioinformatics Analysis - Ingenuity Pathway Analysis (IPA)	Software: Ingenuity Pathway Analysis (IPA)	Software for network analysis
Bryant Unistructure Science Spaces	Gas Chromatograph - Mass Spectrometer (GC - MS) Contact: Julia Crowley-Parmentier	Agilent Technologies 7890A GC and 5975C MSD	Analyze for volatile organics; pyrolysis; MSD and FID
Bryant Unistructure Science Spaces	Sample Concentrator, Purge & Trap Contact: Julia Crowley-Parmentier	Teledyne Tekmar velocity XPT sample concentrator and AQUATek 70 vial autosampler	analyze for highly volatile organics; accessory for the GC-MS
Bryant Unistructure Science Spaces	High Performance Liquid Chromatography (HPLC) Contact: Julia Crowley-Parmentier	Shumatzu	Analyze for non-volatile organics
Bryant Unistructure Science Spaces	Spectrometer Contact: Julia Crowley-Parmentier	Agilent Technologies 7700 series Inductive Coupling Plasma Mass Spectrometer( ICP-MS) with ASX-500 series autosampler	Analyze for trace elements
Bryant Unistructure Science Spaces	Solvent Extractor Contact: Julia Crowley-Parmentier	Dionex ASE 350 Accelerated Solvent Extractor (ASE)	Accelerated extractions
Bryant Unistructure Science Spaces	Concentrator Worstation Contact: Julia Crowley-Parmentier	Caliper LifeSciences Turbo Vap LV Concentration Workstation	Concentrator
Bryant Unistructure Science Spaces	Freeze Dry System Contact: Julia Crowley-Parmentier	Labconco FreeZone 4.5	Freeze dryer
Bryant Unistructure Science Spaces	Spectrophotometer Contact: Julia Crowley-Parmentier	Shimadzu UV 2600	UV/Vis spectrophotometer for quantifying concentrations
Bryant Unistructure Science Spaces	Spectrophotometer	Thermo Scientific AquaMate Plus	UV/Vis spectrophotometer for quantifying concentrations
Bryant Unistructure Science Spaces	Microscope - Electron Contact: Julia Crowley-Parmentier	JEOL JSM 6010LA Scanning Electron Microscope (SEM)	Scanning electron microscope with EDS
Bryant Unistructure Science Spaces	Critical Point Dryer Contact: Julia Crowley-Parmentier	Tousimis Sandri-PVT-3D Critical Point Dryer (CPD)	Maintain structural integrity for soft tissue use of the SEM
Bryant Unistructure Science Spaces	Sputter Coater System Contact: Julia Crowley-Parmentier	Denton Vacuum Desk V gold sputter coater and carbon coater	Coat non-conducting samples with gold or carbon for use on the SEM
Bryant Unistructure Science Spaces	Microscope Contact: Julia Crowley-Parmentier	Zeiss A1 AXIO Polarized Light Microscope and Q imaging RETIGA 400R Imager	Recordable polarized light imaging
Bryant Unistructure Science Spaces	Microscope Contact: Julia Crowley-Parmentier	Zeiss Axiovert 40CFL Inverted Microscope	Recordable inverted microscopy
Bryant Unistructure Science Spaces	Microscope Contact: Julia Crowley-Parmentier	Zeiss Primo Star with AxioCam	Recordable imaging
Bryant Unistructure Science Spaces	Anaerobic Chamber Contact: Julia Crowley-Parmentier	Microbiology International Whitley DG250 Anaerobic Workstation	Simulate anoxic environments for anaerobic work
Bryant Unistructure Science Spaces	Anaerobic Chamber Contact: Julia Crowley-Parmentier	MBRAUN Labstar Anaerobic Glovebox Workstation	simulate anoxic environments for anaerobic work
Bryant Unistructure Science Spaces	PCR Thermal Cycler Contact: Julia Crowley-Parmentier	Bio-Rad PCR Thermocycler C1000 Touch; Fraction Collector model 2110	DNA amplifier
Bryant Unistructure Science Spaces	Biological Safety Cabinet Contact: Julia Crowley-Parmentier	LABGARD ES class II, type A2 Biological Safety Cabinet	Maintain sterility and contain infectious work
Bryant Unistructure Science Spaces	Freezer Contact: Julia Crowley-Parmentier	Thermo Scientific Isotemp Basic U86-13A41 minus 70 degree freezer	Long term storage of biological specimens
CCRI Biology Labs	Autoclave	Consolidated Stills & Sterilizers 24D36	Sterilization. Chamber size is 24inch x36inch, Volume 9.4 cu. Ft
CCRI Biology Labs	Balance - Analytical	Orion Analytical Balance	Weight determination with capacity of 60g.
CCRI Biology Labs	Balance - Top Loading	EK-I Compact Balance	Weight determination (2 units)
CCRI Biology Labs	Incubator	Fisher Scientific Isotemp Digital & Analog Dry Bath Incubator	Provide controlled dry heat environment for clinical & general chemistry applications
CCRI Biology Labs	Electrophoresis System	Bio-Rad Mini-Protean Tetra Cell, Vertical protein electrophoresis gel boxes	Running Protein or DNA polyacrylamide gels
CCRI Biology Labs	Microscope	Lieder MI-500 Series Compound Inverted Microscope	Tissue Culture
CCRI Biology Labs	pH Meter	Thermo Scientific Orion 2-Star Bench Top pH Meter	General purpose measurements
CCRI Biology Labs	Blotting System, Semi-Dry	Shelton Scientific Semi-Dry Blotting System	Transfer of protein, RNA & DNA gels to a solid membrane support for visualization, 24cmx30cm.
CCRI Biology Labs	Spectrophotometer	Thermo Scientific Genesis 20 Visible Spectrophotometer	UV spectrophotometer for quantifying concentrations
CCRI Biology Labs	Transilluminator	FOTODYNE Foto Phoresis UV Transilluminator	Imaging-protein gel analysis, GFP Analysis
CCRI Biology Labs	Incubator - Shaker	Lab Companion IS-971 Floor Model Incubator Shaker	Growing of bacteria, 250 L chamber
CCRI Biology Labs	Biological Safety Cabinet	NuAire Class II Type A2	Maintain sterility and contain infectious work
Center for Computation and Visualization	High Performance Computing Cluster	IBM idataPlex High Performance Computing Cluster	Center for Computation and Visualization (CCV): HPC cycles, Storage, backups, Visualization, data management implementations, server colocation, scientific support
Centralized Research Core Facility	Analyzer - Clinical Chemistry Contact: Kim Andrews, B.A.	Randox RX Daytona Chemistry Analyzer	Clinical chemistry analyzer
Centralized Research Core Facility	Analyzer - Live Cell Contact: Kim Andrews, B.A.	Roche xCELLigence Real-Time Cell Analysis System	Label free live cell analyzer
Centralized Research Core Facility	Biological Safety Cabinet Contact: Kim Andrews, B.A.	NuAire, Laminar Flow Hood	Cell culture facility
Centralized Research Core Facility	Cell Counter Contact: Kim Andrews, B.A.	Nexcellom Cellometer Vision Cell Counter	Automated cell counter
Centralized Research Core Facility	Centrifuge Contact: Kim Andrews, B.A.	Sorvall Evolution High Speed Centrifuge	High speed centrifuge
Centralized Research Core Facility	Centrifuge Contact: Kim Andrews, B.A.	Thermo MultiFuge Centrifuge table-top	Centrifuge
Centralized Research Core Facility	Centrifuge - Ultra Contact: Kim Andrews, B.A.	Beckman Coulter Optima	Ultra centrifuge
Centralized Research Core Facility	Centrifuge - Ultra Contact: Kim Andrews, B.A.	Sorvall Micro Ultra Centrifuge	Ultra centrifuge
Centralized Research Core Facility	Evaporator Contact: Kim Andrews, B.A.	Buchi RotaVap System	Rotary evaporator
Centralized Research Core Facility	Fluorescence Activated Cell Sorter (FACS) Contact: Kim Andrews, B.A.	Becton Dickinson (BD) Biosciences FACS Verse Flow cytometer	FACS
Centralized Research Core Facility	Freeze Dry System Contact: Kim Andrews, B.A.	Labconco 12L Freeze dryer	Freeze dryer
Centralized Research Core Facility	Gel Electrophoresis Contact: Kim Andrews, B.A.	Agilent Offgel Fractionator 3100	Liquid phase Isoelectric Focusing (IEF) System
Centralized Research Core Facility	Gel Electrophoresis Contact: Kim Andrews, B.A.	Bio-Rad 2D Gel System	Two Dimensional (2D) Gel Electrophoresis
Centralized Research Core Facility	Gel Electrophoresis Contact: Kim Andrews, B.A.	Bio-Rad PAGE Electrophoresis System	One Dimensional (1D) Gel Electrophoresis
Centralized Research Core Facility	High Performance Liquid Chromatography - Ultra High (UHPLC) Contact: Kim Andrews, B.A.	Hitachi UPLC System	UPLC
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC) Contact: Kim Andrews, B.A.	GE AKTA Fast Protein Liquid Chromatograph (FPLC)	FPLC
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC) Contact: Kim Andrews, B.A.	Hitachi Analytical HPLC	HPLC
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC) Contact: Kim Andrews, B.A.	Hitachi Prep-HPLC System	HPLC
Centralized Research Core Facility	High Performance Liquid Chromatography (HPLC) Contact: Kim Andrews, B.A.	Teledyne-ISCO CombiFlash System	Flash
Centralized Research Core Facility	Imaging System - Animal Contact: Kim Andrews, B.A.	Caliper/PE IVIS Lumina Whole Animal Imager	Whole animal imager
Centralized Research Core Facility	Imaging System - Gel Imager Contact: Kim Andrews, B.A.	GE Imagescanner II	Gel imager
Centralized Research Core Facility	Imaging System - Gel Imager Contact: Kim Andrews, B.A.	GE Typhoon FLA 9000 Multimode Imager	Gel imager
Centralized Research Core Facility	Imaging System - Gel Imager Contact: Kim Andrews, B.A.	Li-Cor Odyssey IR Imager	IR gel imager
Centralized Research Core Facility	Imaging System - Microarray Contact: Kim Andrews, B.A.	Agilent DNA Microarray Scanner	DNA array
Centralized Research Core Facility	Liquid Chromatography - Mass Spectrometer (LC - MS) Contact: Kim Andrews, B.A.	AB Sciex QSTAR LC/MS System	ESI-TOF MS
Centralized Research Core Facility	Mass Spectrometer Contact: Kim Andrews, B.A.	Shimazu Axima MALDI-TOF MS/MS	MALDI MS
Centralized Research Core Facility	Mass Spectrometer Contact: Kim Andrews, B.A.	Thermo iCAPQ-a ICP-MS	Elemental Analyzer
Centralized Research Core Facility	Microplate Reader Contact: Kim Andrews, B.A.	BMG LabTech Microplate Reader	Fluorescence/UV/VIS
Centralized Research Core Facility	Microplate Reader Contact: Kim Andrews, B.A.	Molecular Devices SpectraMax M2	Fluorescence/UV/VIS
Centralized Research Core Facility	Microplate Reader Contact: Kim Andrews, B.A.	Promega GlowMax System	Chemiluminescence
Centralized Research Core Facility	Microscope Contact: Kim Andrews, B.A.	Nikon Eclipse E600 Upright Microscope	Microscope
Centralized Research Core Facility	Microscope Contact: Kim Andrews, B.A.	Nikon TE2000E /C2 Inverted Confocal	Confocal Microscope
Centralized Research Core Facility	PCR Thermal Cycler Contact: Kim Andrews, B.A.	Applied Biosystems/Life Technologies ABI Vii7- RT-PCR	RT-PCR
Centralized Research Core Facility	PCR Thermal Cycler Contact: Kim Andrews, B.A.	Eppendorf Mastercycler PCR	PCR
Centralized Research Core Facility	Protein Sequencer Contact: Kim Andrews, B.A.	Applied Biosystems Procise 491 Protein Sequencer	N-terminal protein sequencer
Centralized Research Core Facility	Robotic Workstation - Liquid Handler Contact: Kim Andrews, B.A.	BioTek Precision XS Sample Processor	Sample processor
Centralized Research Core Facility	Robotic Workstation - RNA/DNA Contact: Kim Andrews, B.A.	Fuji Film DNA/RNA Isolation System	DNA/RNA isolation
Centralized Research Core Facility	Scintillation Counter Contact: Kim Andrews, B.A.	PerkinElmer Microbeta1450 Scintillation Counter	Scintillation counter
Centralized Research Core Facility	Scintillation Counter Contact: Kim Andrews, B.A.	PerkinElmer Wizard 1470 Gamma Counter	Gamma counter
Centralized Research Core Facility	Spectrometer Contact: Kim Andrews, B.A.	PerkinElmer Luminescence Spectrometer LS55	Fluorescence
Centralized Research Core Facility	Spectrometer Contact: Kim Andrews, B.A.	Jasco 810 Circular Dichroism (CD) Spectropolarimeter	CD
Centralized Research Core Facility	Spectrometer Contact: Kim Andrews, B.A.	Thermo Nicolet 380 Fourier Transformed Infrared Spectrometer (FT-IR)	FT-IR
Centralized Research Core Facility	Spectrophotometer Contact: Kim Andrews, B.A.	Beckman UV/VIS DU800	UV/VIS
Centralized Research Core Facility	Spectrophotometer Contact: Kim Andrews, B.A.	Thermo Scientific NanoDrop 3300	UV/VIS
Centralized Research Core Facility	Spectrophotometer Contact: Kim Andrews, B.A.	Thermo Scientific NanoDrop	UV/VIS
Centralized Research Core Facility	Transfection Platform Contact: Kim Andrews, B.A.	Lonza Nucleofactor System	High-throughput transfection
Centralized Research Core Facility	Water Purification System - Deionized (DI) Contact: Kim Andrews, B.A.	Millipore Milli-Q Water System	DI water System
Centralized Research Core Facility	Western Blotting System Contact: Kim Andrews, B.A.	Bio-Rad Turbo Trans Blot system	Western Blotting
Centralized Research Core Facility	Western Blotting System Contact: Kim Andrews, B.A.	Life Technologies BenchPro Western System	Western Blotting processor
Centralized Research Core Facility	Western Blotting System Contact: Kim Andrews, B.A.	Protein Simple Simon Western	Liquid phase Western Blotting
Core Research Laboratories	Cryostat Contact: Paul Monfils	Reichert-Jung Cryocut 1800	Frozen tissue sectioning (used with Superfrost/Plus microscope slides (approximately 4-10 microns).
Core Research Laboratories	Fluorescence Activated Cell Sorter (FACS) Contact: Paul Monfils	Becton Dickinson (BD) Biosciences FACS Vantage Flow Cytometer	High-speed cell sorter. Two lasers analyze cells on 8 parameters. Side/ forward light scatter. 6 different fluorescent color detection. Simultaneously sort up to four populations of cells. Sort 1+ cell type(s) into 6, 24, and 96 well tissue culture plates.
Core Research Laboratories	Fluorescence Activated Cell Sorter (FACS) Contact: Paul Monfils	Becton Dickinson (BD) Biosciences FACSort Flow Cytometer	Analytical flow cytometer. Two lasers analyze cells on 6 parameters. Side/ forward light scatter. 4 different fluorescent color detection.
Core Research Laboratories	Histology/Tissue Processing - Biosafety Cabinet Contact: Paul Monfils	Laminar Flow Hood	Filter capable of removing 99.97% of particles greater than 0.3 microns.
Core Research Laboratories	Histology/Tissue Processing - Knife Sharpener Contact: Paul Monfils	Hecker Instruments, Inc. Knife Sharpener	Used to sharpen microtome/cryostat knife.
Core Research Laboratories	Histology/Tissue Processing - Microwave Oven Contact: Paul Monfils	Sharp Microwave Oven	Tissue microwave fixation.
Core Research Laboratories	Histology/Tissue Processing - Oven Contact: Paul Monfils	Fisher Scientific Oven	Used to melt paraffin from paraffin- embedded sections.
Core Research Laboratories	Histology/Tissue Processing - Paraffin Embedding Workstation Contact: Paul Monfils	Miles Scientific Tissue-Tek III	Paraffin embedding sample station (tissue, bone, cell pellet, etc.).
Core Research Laboratories	Histology/Tissue Processing - Tissue Processor Contact: Paul Monfils	Miles Scientific Tissue-Tek-VIP Tissue Processor	Automated sample processing (tissue, bone, cell pellet, etc.) for paraffin embedding purposes.
Core Research Laboratories	Hybridization Oven Contact: Carol Ayala	Panomics-Luminex Hybridization oven	Horizontal air flow oven for optimal temperature uniformity.
Core Research Laboratories	Imaging System - Camera Contact: Ginny Hovnesian	Diagnostics SPOT 110-2 Digital Camera	Digital Imaging of samples.
Core Research Laboratories	Imaging System - Camera Contact: Ginny Hovnesian	Olympus SPOT IDEA 3.0 MP Digital Camera	Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Core Research Laboratories	Imaging System - Camera Contact: Ginny Hovnesian	SPOT RT3 Slider -43C F-MT Digital Camera	Attached to Nikon TE-800. Digital Imaging of samples. Ideal for brightfield color imaging, fluorescence microscopy, FISH, GFP imaging, immuno- fluorescence, 3D convolution. CCD cooled to -43.3. 1.92 MP. 1-16x. 14-bit x 20MHz capture, 40MHz live mode, interline progressive scan, FireWire interface.
Core Research Laboratories	Imaging System - Dark Room Contact: Paul Monfils	Dark Room Related equipment eg., automatic processors, dryers, et al	Sample photo development.
Core Research Laboratories	Imaging System - Photo Enlarger Contact: Carol Ayala	Durst Laborator 1200 Photographic Enlarger	Sample digital imaging using high performance enlarger.
Core Research Laboratories	Microscope Contact: Carol Ayala	Bausch Lomb Stereomicrosopes	Visualization with incident light illumination.
Core Research Laboratories	Microscope Contact: Ginny Hovnesian	NIKON E-800 Fluorescent /Brightfield Microscope	Fluorescence/Brightfield- micro- scope slides only. CFI60 optical system. 0.5x magnification with 50mm field of view. Can be coupled with 2x projection lens to permit macrophotography at 1:1 magnification. Tube lens focal length of 200mm. 10 types of condensers available.
Core Research Laboratories	Microscope Contact: Ginny Hovnesian	Nikon TE 200 Inverted Fluorescent/Brightfield Microscope	Fluorescence/Brightfield Microscope- petri dish/microscope slides on cell/slice culture etc. Phase contrast and fluorescence.
Core Research Laboratories	Microscope Contact: Paul Monfils	Olympus BHTU Upright Light Microscope	Light Microscope for viewing tissue or cell samples on microscope slides. 45mm parfocal distance system, corrected for a mechanical tube length of 160mm. Two types of standard objectives, D Achromats and D Plan Achromats, magnifications of 4x, 10x, 20x, 40x, 100x. FN20. Equipped for epifluorescence microscopy.
Core Research Laboratories	Microscope Contact: Paul Monfils	Olympus IMT-2 Inverted Light Microscope	Light Microscope use to view cell/slice/tissue culture samples (microscope slide or petri dish). Inverted research microscope equipped with phase contrast optics.
Core Research Laboratories	Microscope Contact: Carol Ayala	Zeiss S-16 Light Microscope	Light Microscope used to view 1 micron sectioned resin-embedded samples.
Core Research Laboratories	Microscope	NIKON C1Si Spectral Live Cell Confocal Inverted Microscope System	For use with microscope slide. Four diode lasers that excite at 402, 488, 561, & 638 and has spectral capabilities. Suitable for tissue, live cell imaging, time events, FRAP, FRET, deconvolutions, colocalization analysis and 3D reconstructions.
Core Research Laboratories	Microscope - Electron Contact: Carol Ayala	Morgagni 268 Fully Digitized Transmission Electron Microscope (TEM)	Ultrastructural analysis (tissue, cells) on stained ultra-thin sections contrasted with uranyl acetate and lead citrate. Examined with Morgagni 268 transmission electron microscope that is fully digitized, high performance, 100 kv, and images collected with an AMT Advantage 542 CCD camera system.
Core Research Laboratories	Microtome Contact: Carol Ayala	Bausch Lomb Ultramicrotome	Sectioning resin-embedded tissue; micron-nm thickness.
Core Research Laboratories	Microtome Contact: Paul Monfils	Reichert-Jung Microtome	Paraffin embedded tissue sectioning (approximately 2-20 microns).
Core Research Laboratories	Vibratome Contact: Carol Ayala	Bausch Lomb Vibratomes	Sectioning agarose-embedded tissue.
Core Research Laboratories	Vibratome Contact: Paul Monfils	Vibratome 3000 Sectioning System	Fresh tissue sectioning. Thickness: 3- 20 microns.
DNA Sequencing Facility	DNA Sequencer	Illumina Sequencing System, GAIIx	DNA, transcriptome and gene regulation analysis
DNA Sequencing Facility	DNA Sequencer	Illumina Sequencing System, HiSeq2000	DNA, transcriptome and gene regulation analysis
DNA Sequencing Facility	DNA Sequencer	Illumina Sequencing System, HiSeq2500	DNA, transcriptome and gene regulation analysis
Environmental Chemistry Facility	Analyzer - Discrete Analyzer	Westco Smartchem 200	Used to determine Nitrate/Nitrite, Phosphate, Ammonia, Silicate, and other nutrient concentrations in water samples and soil extracts.
Environmental Chemistry Facility	Analyzer - Elemental Analyzer	CE Elantech, Carbon-Nitrogen NC2100	Analysis of carbon, nitrogen, and sulfur concentration of solid samples
Environmental Chemistry Facility	Analyzer - Inorganic Carbon Analyzer	UIC, INC Inorganic Carbon Analyzer	Measures total inorganic carbon by automated acidification and coulometric detection in a wide variety of sample matrices. Solid samples ranging from low ppm to 100% inorganic carbon can be analyzed with this system.
Environmental Chemistry Facility	Analyzer - Mercury Analyzer	Milestone DMA-80 Direct Mercury Analyzer	Determines mercury content of solid and liquid samples.
Environmental Chemistry Facility	Analyzer - Water Isotope	Picarro L1102-I	Measures delta deuterium/hydrogen (D/H) ratio and delta 18O/16O in liquid water
Environmental Chemistry Facility	Freeze Dry System	Labconco FreeZone 6 Liter	For removing water and other solvents from frozen samples by sublimation.
Environmental Chemistry Facility	Liquid Chromatography System	Dionex DX500	Ion chromatography analysis of ions in marine and freshwater samples
Environmental Chemistry Facility	Microwave Digestion System	Milestone Ultrawave	Used to digest solid samples (soils, sediments, rocks, plants, tissues), for elemental analysis.
Environmental Chemistry Facility	Spectrometer - Atomic Absorption Spectrometer-Graphite Furnace (GFAAS)	Perkin Elmer AAnalyst 600 Graphite Furnace	This spectrometer is useful for measuring trace levels of metals in water and soil.
Environmental Chemistry Facility	Spectrometer - Atomic Emission Spectrometer (AES)	Jobin Yvon JY2000 Ultrace Inductively coupled plasma atomic emission spectrometer (ICP-AES)	Analysis of most elements with atomic weights above 10.
Environmental Chemistry Facility	X-Ray Fluorescence - Handheld	Innov-X Systems Alpha 4000 Handheld	Non-destructive elemental analysis on a variety sample types for concentrations of some metalsranging from about 20 ppm to 10%.
Environmental Chemistry Facility	X-ray Fluorescence Spectrometer	Phillips PW1480 wavelength dispersive sequential diffractometer with a PW1510 autosampler	This system is used mainly for elemental analysis of finely ground sediments, soils, or rocks (sample sizes >3 g), prepared as pressed powders.
Flow Cytometry and Sorting Facility	Fluorescence Activated Cell Sorter (FACS)	Becton Dickinson (BD) Biosciences FACS Aria II	Cell counting, sorting, biomarker detection
Genomics & Sequencing Center	Bioanalyzer Contact: Janet A. Atoyan, Genomics Technician	Agilent Bioanalyzer 2100	Provides fast and automated separation, sizing and quantification of DNA, RNA and proteins by miniaturized Lab-on-a-Chip electrophoresis
Genomics & Sequencing Center	Bioinformatics Analysis - DNA Sequence and Protein Analysis Contact: Janet A. Atoyan, Genomics Technician	Software: DNAStar Lasergene Core Suite	Comprehensive suite of software modules for DNA, RNA, and protein sequence analysis
Genomics & Sequencing Center	Bioinformatics Analysis - Next Generation DNA Sequence Assembly Contact: Janet A. Atoyan, Genomics Technician	Software: CLCbio Genomics Workbench	Software for analyzing, comparing, and visualizing Next Generation Sequencing data
Genomics & Sequencing Center	Centrifuge Contact: Janet A. Atoyan, Genomics Technician	Beckman Coulter Allegra 25R Refrigerated Centrifuge	Centrifuge for pelleting cells, tissues and macromolecules
Genomics & Sequencing Center	Centrifuge Contact: Janet A. Atoyan, Genomics Technician	Thermo Savant DNA110 SpeedVac Vacuum Centrifuge	Centrifugal concentration system for drying low-volume ethanol or isopropanol precipitates of DNA and RNA
Genomics & Sequencing Center	Cryostat Contact: Janet A. Atoyan, Genomics Technician	Vibratome 5000 Advanced Cryostat	Performs histological sectioning of unfixed frozen cells and tissues.
Genomics & Sequencing Center	Disrupter Contact: Janet A. Atoyan, Genomics Technician	Covaris S220 High Performance Ultrasonicator	Automated acoustic disruption and homogenization of cells and tissue samples using focused ultrasonic energy at 500 KHz. Performs DNA Shearing
Genomics & Sequencing Center	Disrupter Contact: Janet A. Atoyan, Genomics Technician	QIAGEN TissueLyser	Provides rapid and efficient disruption of cells and tissues
Genomics & Sequencing Center	DNA Sequencer Contact: Janet A. Atoyan, Genomics Technician	Applied Biosystems 3130xl & 3500xl Genetic Analyzers	DNA Sanger Sequencing & Fragment Analysis: Fluorescence-based instruments utilizing capillary electrophoresis for DNA sequencing and fragment analysis
Genomics & Sequencing Center	DNA Sequencer Contact: Janet A. Atoyan, Genomics Technician	Illumina MiSeq DNA NextGen Sequencing	Performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting
Genomics & Sequencing Center	Electrophoresis System Contact: Janet A. Atoyan, Genomics Technician	Sage Science BluePippin DNA Electrophoresis System	A preparative electrophoresis platform that separates and extracts DNA fragments using pre-cast gel cassettes
Genomics & Sequencing Center	Fluorometer Contact: Janet A. Atoyan, Genomics Technician	Invitrogen Qubit	Fluorometer that uses fluorescent dyes bound to specific molecules to quantify DNA, RNA and proteins
Genomics & Sequencing Center	Imaging System - Camera Contact: Janet A. Atoyan, Genomics Technician	Zeiss AxioCam HRc high-resolution imaging systems	A digital Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module. For use on the AxioImager upright light microscope
Genomics & Sequencing Center	Library Preparation System Contact: Janet A. Atoyan, Genomics Technician	IntegenX Apollo 324 System NextGen Sequencing (NGS) Library Preparation System	Automated liquid handling instrument dedicated to the preparation of sample libraries for Next Generation Sequencing
Genomics & Sequencing Center	Microarray Platform Contact: Janet A. Atoyan, Genomics Technician	BioLog OmniLog Phenotype Microarray System Plate Incubator/Reader	Uses Phenotype Microarrays in microtiter plates to test for unique phenotypes or cell functions
Genomics & Sequencing Center	Microscope Contact: Janet A. Atoyan, Genomics Technician	Zeiss AxioImager M2 Upright Light Microscope	For use with the AxioImager upright light microscope equipped for digital image acquisition with a Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module
Genomics & Sequencing Center	PCR Thermal Cycler Contact: Janet A. Atoyan, Genomics Technician	Agilent Mx3005P and Roche LC480 qPCR Systems	3 Quantitative PCR (qPCR) instruments. Used for highly accurate qualitative and quantitative detection of nucleic acids and gene expression .
Genomics & Sequencing Center	PCR Thermal Cycler Contact: Janet A. Atoyan, Genomics Technician	Eppendorf Mastercycler ep Gradient S and MJ Research PTC-100	(3) Thermal cyclers in 96-well format; peltier elements control the temperature of the block for PCR chemistry
Genomics & Sequencing Center	PCR Workstation Contact: Janet A. Atoyan, Genomics Technician	AirClean Systems 600 PCR Workstation	Combination workstation provides an ISO 5 (FS209E) Class 100 clean air environment and UV light sterilization
Genomics & Sequencing Center	Robotic Workstation - Automated Pipetting Contact: Janet A. Atoyan, Genomics Technician	Eppendorf epMotion 5075 VAC Pipetting Workstation	Automated pipetting workstation enables fast and reproducible liquid handling for a variety of applications
Genomics & Sequencing Center	Robotic Workstation - Sample Preparation Contact: Janet A. Atoyan, Genomics Technician	QIAGEN QIAcube Spin Column Robot	Automated protocols for purification of plasmid DNA, genomic DNA, RNA, viral nucleic acids, and proteins
Genomics & Sequencing Center	Spectrophotometer Contact: Janet A. Atoyan, Genomics Technician	Thermo Scientific NanoDrop 8000	Spectrophotometer that accurately measures up to eight individual 1-2 microliter samples simultaneously
Genomics Facility	Bioanalyzer	Agilent Bioanalyzer 2100	Microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cells
Genomics Facility	Capillary Electrophoresis	Advanced Analytical, Fragment Analyzer	Analyze DNA fragments for Next-Gen Sequencing, genotyping, checking RNA quality and quantity, and working with microsatellite simple sequence repeats (SSRs).
Genomics Facility	Cell Counter	Life Technologies Automated Countess Cell Counter	Measure cell count and viability (live, dead, and total cells) using the standard trypan blue technique.
Genomics Facility	Centrifuge	Sorvall Legend T Benchtop	Low to medium speed centrifugation
Genomics Facility	Centrifuge - Ultra	Beckman Coulter Optima Max	High speed centrifugation with MLA130, TLA110 & TLA100 Rotors
Genomics Facility	Disrupter	Covaris S220 High Performance Ultrasonicator	DNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization
Genomics Facility	Fluorescence Activated Cell Sorter (FACS)	Becton Dickinson (BD) Biosciences FACS Calibur	Flow cytometry cell analysis and cell sorting
Genomics Facility	Hybridization Oven	Agilent G2534A	Microarray hybridization oven
Genomics Facility	Imaging System	LiCor Odyssey Clx Infrared	Western blot analysis, EMSA, protein arrays, In-Cell Western Assays, On-Cell Westerns, in vivo imaging, Coomassie gel documentation, DNA gel documentation, and tissue section analysis.
Genomics Facility	Imaging System	Molecular Dynamics Typhoon 9410	Imaging system for gel sandwiches agarose and polyacrylamide gels membranes, microplates and microarrays.
Genomics Facility	Microarray Platform	Affymetrix Gene Chip Instrument System	A fully integrated platform for Affymetrix microarrays
Genomics Facility	Microarray Scanner	Molecular Devices GenePix Scanner 4000B	Two color microarray scanner
Genomics Facility	Microplate Reader	Molecular Devices Spectra Max M5	Detects UV-Visible Absorbance (Abs), Fluorescence Intensity (FI), Time-Resolved Fluorescence (TRF), Fluorescence Polarization (FP), Glow Luminescence (Lumi)
Genomics Facility	PCR Thermal Cycler	Applied Biosystems 7900 Fast Real Time PCR System	96- and 384-well fast real time, quantitative PCR formats with fully automated robotic loading
Genomics Facility	PCR Thermal Cycler	Applied Biosystems viia-7-real-time-system	Medium to high throughput 96- and 384-well fast real time quantitative PCR formats with fully automated robotic loading, medium to high throughput
Genomics Facility	PCR Thermal Cycler	Eppendorf Gradient Mastercycler	Gradient cycler enables the temperature across the entire block to be varied within a range of up to 20 C; it can be programmed with every temperature step. For use by genomics facility personnel.
Genomics Facility	Spectrophotometer	Thermo Scientific NanoDrop 1000	A microvolume spectrophotometer for measuring DNA, RNA, and protein.
Genomics Facility	Technical Assistance - Affymetrix Microarray	Service	Service to provide Affymetrix gene expression array service
Genomics Facility	Technical Assistance - Genomics and DNA Sequencing Training	Service	Service to provide Genomics and DNA Sequencing Training
Genomics Facility	Technical Assistance - Next Generation (NextGen) Sequencing (NGS)	Service	Service to provide Illumina platform based NextGen sequencing
Leduc Bioimaging Facility	Bioinformatics Analysis - Molecular Devices, MetaMorph	Software: Molecular Devices, MetaMorph	Software for microscopy automation & image analysis
Leduc Bioimaging Facility	Critical Point Dryer	Ladd Research Industries	Removes liquid from biological specimens for SEM
Leduc Bioimaging Facility	Glow Discharge Unit	Emitech K100X	Adds a charge to make TEM samples hydrophilic
Leduc Bioimaging Facility	Microscope	Leica TCS SP2 Confocal	Optical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Olympus MultiPhoton Laser Scanning	Deep optical sectioning of fluorescently labeled samples with SIM photoactivation
Leduc Bioimaging Facility	Microscope	Zeiss Axiovert 200M Fluorescence	Imaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss Axiovert 200M Fluorescence	Imaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss LSM 410 Confocal	Optical sectioning of samples labeled with fluorescent indicators with Microcosm UV laser upgrade
Leduc Bioimaging Facility	Microscope	Zeiss LSM 510 Meta Confocal	Optical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss LSM 710 Confocal	Optical sectioning of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope	Zeiss Lumar Stereo Fluorescence	Imaging of samples labeled with fluorescent indicators
Leduc Bioimaging Facility	Microscope - Electron	Hitachi S-2700 Scanning Electron Microscope (SEM)	Transmission electron microscopy with PCI Digital Imaging Accessory
Leduc Bioimaging Facility	Microscope - Electron	Philips 410 Transmission Electron Microscope (TEM)	Scanning electron microscopy with AMT Camera Accessory
Leduc Bioimaging Facility	Microtome	Reichert Ultramicrotome	Ultrathin sectioning for TEM
Leduc Bioimaging Facility	Microtome Diamond Knife Set	Diatome DKS	Used on Reichert microtome to cut ultrathin sections for TEM
Leduc Bioimaging Facility	Sputter Coater System	Emitech K550	Covers an EM specimen with a thin layer of conducting material
Leduc Bioimaging Facility	Technical Assistance - Bioimaging	Service	Service to provide Bioimaging Technical Assistance
Leduc Bioimaging Facility	Technical Assistance - Bioimaging Training	Service	Service to provide Bioimaging Training
Magnetic Resonance Imaging Facility	Magnetic Resonance Imaging (MRI) Scanner	Siemens 3 Tesla TIM Trio.	Brain structure and function in normal and clinical populations as well as studies of other body systems, non-invasive animal imaging and materials science.
Marine Science Research Facility	Analyzer - Dissolved Gas Contact: Malcolm McFarland	Bay Instruments Membrane Inlet Mass Spectrometer- Dissolved Gas Analyzer	Mass Spectrometer: Quantifies dissolved gases
Marine Science Research Facility	Analyzer - Multiparameter Water Analyzer Contact: Malcolm McFarland	YSI Professional Plus Hand Held Multiparameter Water Meter	Measures temperature, salinity, dissolved oxygen (DO), and pH
Marine Science Research Facility	Analyzer - Nutrient Contact: Malcolm McFarland	Lachat QuickChem 8500 Flow Injection Nutrient Auto Analyzer	Measures dissolved nutrients in water, Ammonia, Phosphate, Nitrite, Nitrate, and Silicate
Marine Science Research Facility	Aquatic Culture - Algae and Live Feed Room Contact: Danielle Duquette	Various manufacturers	K-walls, small rearing tanks for live feed, flowing seawater and freshwater
Marine Science Research Facility	Aquatic Culture - Phytoplankton Culture Wheels Contact: Danielle Duquette	Various manufacturers	Motorized and water driven, clear plexiglass, ambient and experimental temperature control, can accommodate culture bottles of differing sizes (1-3L)
Marine Science Research Facility	Dechlorination System - Freshwater Contact: Danielle Duquette	Various manufacturers	2 Freshwater dechlorination tanks
Marine Science Research Facility	Disrupter Contact: Malcolm McFarland	Biospec Mini Bead Beater	Shakes tubes with beads to disrupt cells, DNA , RNA
Marine Science Research Facility	Disrupter Contact: Malcolm McFarland	Branson Digital Ultasonic Liquid Sonifier	Disrupts cells
Marine Science Research Facility	Environmental Chamber Contact: Danielle Duquette	EnvironAir Environmental Chamber	100 sq ft Temperature control, Two range 4-24 C, Two range -4-24 C (to simulate polar conditions), On generator back up and emergency monitoring systems. (4 Units)
Marine Science Research Facility	Flowing Seawater System Contact: Danielle Duquette	Various manufacturers	Raw-Ambient temperature and Filtered- Chilled, Heated, Ambient. UV treated, air supply, emergency monitoring systems
Marine Science Research Facility	Fluorescence Activated Cell Sorter (FACS) Contact: Andrea Drzewianowski	Becton Dickinson (BD) Biosciences Influx Flow Cytometer and Cell Sorter	Measures light scatter and fluorescence of cells. Sorts cells based on measured properties.
Marine Science Research Facility	Fluorometer Contact: Malcolm McFarland	Satlantic Fluorescence Induction Relaxation Fluorometer (FIRE)	Measures variable fluorescence in phytoplankton
Marine Science Research Facility	Fluorometer Contact: Malcolm McFarland	Turner Designs 10-AU (Chlorophyll) Field Fluorometer	A rugged, field-portable instrument that can be set up for continuous-flow monitoring or discrete sample analyses. Measures fluorescence of samples. Set up for chlorophyll fluorescence both extracted and in vivo
Marine Science Research Facility	Fluorometer Contact: Malcolm McFarland	Life Technologies Qubit Fluorometer	Quantifies DNA, RNA, and protein
Marine Science Research Facility	Freezer - Walk-in Contact: Danielle Duquette	-20 C Walk-In Freezer	185 sq ft Long term storage, On generator back up and emergency monitoring systems
Marine Science Research Facility	Homogenizer Contact: Malcolm McFarland	Polytron Homogenizer PT-10-35-GT	Rapidly breaks down plant and animal tissue for chemical analysis, prepares emulsions and samples for titrations, and extracts pesticides in soil samples. Provides fast, reproducible homogenization, emulsion, dispersion, and mixing, with consistent sample-to-sample uniformity.
Marine Science Research Facility	Imaging System - Camera Contact: Malcolm McFarland	Allied Digital Stingray Firewire Microscope Camera	Video and still images C-mount
Marine Science Research Facility	Imaging System - Fluid Particle Imaging Contact: Malcolm McFarland	Fluid Imaging Technologies FlowCam	Imaging Particle Analysis: Images particles suspended in solution.
Marine Science Research Facility	Incubator Contact: Malcolm McFarland	Percival Incubator/Growth Chamber	Temperature and light controlled incubator for environmental applications
Marine Science Research Facility	Microplate Reader Contact: Malcolm McFarland	Molecular Devices Spectramax M5	Measures Fluorescence Intensity, Absorbance, Time Resolved Fluorescence, Fluorescence Polarization and Luminescence in cuvettes and multiple sized microplates.
Marine Science Research Facility	Microscope Contact: Malcolm McFarland	Nikon inverted Microscope	Microscopy: Works with Stingray Camera
Marine Science Research Facility	Microscope Contact: Malcolm McFarland	Olympus SZX16 Stereo Microscope	Microscopy. Works with Stingray Camera
Marine Science Research Facility	PCR Thermal Cycler Contact: Malcolm McFarland	Eppendorf Master Cycler Pro	Replicates DNA
Marine Science Research Facility	PCR Thermal Cycler Contact: Malcolm McFarland	Stratagene QPCR Mx3000P	Instrument for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Quantitative PCR Filters- FAM/Syber Green, Rox, Hex, CY3, CY5
Marine Science Research Facility	Photoperiod controller Contact: Danielle Duquette	Various manufacturers	Wattstopper controller(Blount), Various individual timers
Marine Science Research Facility	Pier Access Contact: Danielle Duquette	Access to Graduate School of Oceanography pier	Access to pier for deployment, collection, testing. Water depths 18-15 feet to intertidal zone
Marine Science Research Facility	Radiometer Contact: Malcolm McFarland	Biospherical Instruments Quantum Scalar Laboratory (QSL) Radiometer - PAR Light Meter	Measures Photosynthetically Active Radiation (PAR)
Marine Science Research Facility	Shaker Contact: Malcolm McFarland	Thermo Max-Q Orbital Shaker Table	Orbital shaker with 18x24 in platform and variety of clamps
Marine Science Research Facility	Shaker Contact: Malcolm McFarland	Thermo Max Q Incubated Shaker	Heated incubated shaker
Marine Science Research Facility	Spectrometer Contact: Malcolm McFarland	Ocean Optics Jaz Spectrometer	Optical sensing instrumentation that measures light wavelengths. Its unique features and expandable platform makes it uniquely suited for field applications, remote sensing, process flow and quality assurance.
Marine Science Research Facility	Spectrophotometer Contact: Malcolm McFarland	Thermo Scientific NanoDrop 1000	Microvolume UV-Vis spectrophotometer that quantifies DNA, RNA, and protein from small 1-2 microliter sample size
Marine Science Research Facility	Tank - Laminar Flow Contact: Danielle Duquette	Laminar Flow Tank	1000 gal, Seawater or Freshwater, Multiple speeds with precision control. Experimental chamber visable from 5 sides
Marine Science Research Facility	Tank - Mesocosm Contact: Danielle Duquette	Various manufacturers	10, 5 ft deep outdoor mesocosms, with available raw ambient seawater flow
Marine Science Research Facility	Vacuum Manifold Contact: Malcolm McFarland	Vacuum Filter Manifold	Allows for filtration of 5 ports simultaneously, 25 and 47 mm filter cups available
Marine Science Research Facility	Worksation - Marine General Wet Lab Contact: Danielle Duquette	Various manufacturers	3 Buildings, 7,000 sq ft indoor, and nearly unlimited outdoor space, Multiple insulated tank sizes, various sized aquaria, possible to perform simultaneous replicates
Marine Science Research Facility	Workstation - Marine Pathology and Transgenics Laboratory and Systems Contact: Danielle Duquette	Various manufacturers	Ozone treated effluent and separate effluent drain
Mass Spectrometer Analytical Facility	Mass Spectrometer Contact: Alberto Saal	Thermo Scientific Multi-collector inductively coupled plasma mass spectrometer, ICP-MS, Neptune Plus	This is a multi-collector ICP-MS equipped with nine Faraday cups and eight ion counters, which allows us to monitor multiple masses simultaneously providing precise isotope ratio measurement.
Mass Spectrometer Analytical Facility	Mass Spectrometer Contact: Alberto Saal	Thermo Scientific Quadrupole inductively coupled plasma mass spectrometer, ICP-MS, X-series-2	This is a single collector ICP-MS that allows us to measure precise elemental composition at sub-ppb level concentration.
Mass Spectrometer Analytical Facility	Laser Ablation Contact: Alberto Saal	Photon-machines Analyte G2, 193 nm excimer laser ablation	This 193 nm wave-length excimer laser allows us to perform in-situ analysis on a solid sample with a beam diameter as small as 3 µm. To determine the elemental abundances the laser is coupled with the single collector inductively coupled plasma mass spectrometer ICPMS and to determine the isotope ratios the laser is coupled with multi collector ICPMS.
Mass Spectrometer Analytical Facility	Clean lab, Trace metal free Contact: Alberto Saal	Pico Trace	This Clean Lab is equipped with Millipore water filtration system that provides greater than 18MΩ Milli-Q water. The working stations in this Clean Lab meet ISO class 4 standard (equivalent to FS class 10) allowing us to perform ultra-low blank chemical analysis.
Mass Spectrometry Facility	Gas Chromatograph - Mass Spectrometer (GC - MS)	Hewlett-Packard (Agilent) GCD 1800C	This system is suitable for separation of complex mixtures by gas chromatography (GC) and identification by mass spectrometry. It is limited to low molecular weight and volatile molecules (mass limit 450 Da).
Mass Spectrometry Facility	Liquid Chromatography - Mass Spectrometer (LC - MS)	Agilent 6230 Mass TOF	This instrument can detect and identify compounds in amounts smaller than two trillionths of a gram (2 picograms), making the Agilent 6230 a powerful tool for food safety, toxicology and other measurements where minute amounts of compounds must be identified.
Mass Spectrometry Facility	Mass Spectrometer	Applied Biosystems Voyager DE PRO MALDI-TOF	The Voyager DE PRO is a time-of-flight (TOF) mass spectrometer equipped with a matrix-assisted laser desorption ionization (MALDI) ion source. This instrument is routinely used for analysis of organic molecules, natural products, and macromolecules, including recombinant proteins, oligonucleotides, polysaccharides and synthetic polymers.
Mass Spectrometry Facility	Mass Spectrometer	JEOL JMS-600H double focusing magnetic sector	The JMS-600H is a compact double-focusing, high-resolution, magnetic sector mass spectrometer. This instrument is equipped with electron impact ionization (EI), Chemical Ionization (CI), and fast atom bombardment ionization (FAB) for characterization of synthetic organic, inorganic, and biological molecules. This instrument is also used for routine exact mass measurement of organic molecules.
Mass Spectrometry Facility	Mass Spectrometer	Thermo LXQ linear ion trap with Surveyor HPLC system	The LXQ has capabilities similar to the conventional 3D ion trap such as LCQ Deca. It is based on linear ion trap technology that has faster cycle time. It is capable of data-dependent LC/MSn analysis.
Mass Spectrometry Facility	Mass Spectrometer	Thermo LCQ Deca XP Max ion trap with Shimadzu HPLC system	The LCQ Deca XP Max is equipped with electrospray (ESI) and APCI ionization sources. It is capable of mass analysis of a broad range of molecules that are relatively polar, nonvolatile and thermally labile. This instrument is used for routine molecular weight determination of compounds from organic, inorganic, natural products, small proteins and peptides, and oligonucleotides.
Media Prep Kitchen	Media Prep Kitchen for Drosophila	Service	Service to provide bottles and vials of Drosophila media
Molecular Biology and Imaging Core	Fluorescence Activated Cell Sorter (FACS)	Becton Dickinson (BD) Biosciences FACSCanto	Analytical Flow Cytometer: 2 lasers, 6 colors
Molecular Biology and Imaging Core	Gel Imager	Bio-Rad Chemidoc XRS	The ChemiDoc XRS+ system is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab software to optimize imager performance for fast, integrated, and automated image capture and analysis of various samples.
Molecular Biology and Imaging Core	Gel Imager	Bio-Rad Molecular Imager FX system	Imager with 50 micron resolution and a 5 order of magnitude linear dynamic range for fluorescence and radioisotopic imaging. You can also image and accurately quantitate chemiluminescent samples.
Molecular Biology and Imaging Core	Magnetic cell sorter	Miltenyi AutoMACS	Automated cell sorter, for separating cell suspensions labeled with magnetic beads
Molecular Biology and Imaging Core	Microplate Reader	Molecular Devices Spectramax Gemini EM Fluorescence Microplate Reader	Enables top and bottom reading of microplates over a greater range of fluorescence intensities—all without the use of filters.
Molecular Biology and Imaging Core	Microplate Reader	Perkin Elmer TopCount NXT Microplate Scintillation and Luminescence Counter	TopCount NXT analyzes two, six, or twelve samples at a time, and counts samples in 24-, 96-, and 384-well microplates, as well as microcentrifuge tubes. It can count gammas, betas, or luminescent samples.
Molecular Biology and Imaging Core	Microscope	Leica MZ FLIII Stereo Fluorescent dissection microscope	Dissection microscope with Leica color camera DC300F.
Molecular Biology and Imaging Core	Microscope	Nikon 80i Upright Fluorescence Microscope	Upright microscope with color CCD camera Spot Insight 2
Molecular Biology and Imaging Core	Microscope	Nikon TE2000E Inverted fluorescence,	A live cell imaging microscope, with cooled CCD camera Roper CoolSnap HQ
Molecular Biology and Imaging Core	Microscope	Zeiss AxioImager M2 Upright Microscope,	Upright microscope with color CCD camera AxioCam MRC.
Molecular Biology and Imaging Core	Microscope	Nikon TE2000E Inverted fluorescence,	A Multicolor fluorescence widefield microscope, with stage incubator, specialized in live cell imaging
Molecular Biology and Imaging Core	PCR Thermal Cycler	Applied Biosystems ABI 7500	96-well quantitative PCR
Molecular Biology and Imaging Core	Spectrophotometer	Bio-Rad smartspec	90-260 V, UV/visible benchtop spectrophotometer for nucleic acid and protein quantitation, wavelength range 200–800 nm, built-in thermal printer
Molecular Biology and Imaging Core	Spectrophotometer	Thermo Scientific NanoDrop 2000	A full spectral microvolume UV-Vis analysis spectrophotometer for measuring DNA, RNA, and protein.
Molecular Biology and Imaging Core	Suspension Array System	Bio-Rad BioPlex 200	Detection and quantification of multiple analytes (proteins and peptides, or nucleic acids) in a single sample volume.
Molecular Characterization Facility	Nuclear Magnetic Resonance (NMR) Spectrometer Contact: Prof. David Rowley	Agilent NMRS 500 with OneNMR Probe	NMR Spectroscopy
Molecular Pathology	Bioanalyzer	Agilent Bioanalyzer MX3005P	Two assay principles: electrophoresis and flow cytometry. Minimal sample consumption: 1-4 microliters. Digital data. Contamination-free switch of methods.
Molecular Pathology	Biological Safety Cabinet	HEPA filter and NuAire laminar flow hood	Filter capable of removing 99.97% of particles greater than 0.3 micronss.
Molecular Pathology	Biospecimen Banking - Freezer	ThermoForma Freezer - 80 C #8606	Sample storage
Molecular Pathology	Biospecimen Banking - Freezer	ThermoForma Freezer -20 C #3801	Sample storage
Molecular Pathology	Biospecimen Banking - Freezer	ThermoForma Refrigerator #3771	Sample storage
Molecular Pathology	Biospecimen Banking - Refrigerator	ThermoForma Ultra 932 Lo Freezer -80 C (2)	Sample storage
Molecular Pathology	Centrifuge	Eppendorf 5424 Microcentrifuge	Aerosol-tight rotor. Max rcf: 20,238 x g. Automatic lid opening following application sequence. Low access height: 23 cm. Short spin, rpm/rcf setting as required
Molecular Pathology	Centrifuge	ThermoForma refrigerated Microcentrifuge	Working temperatures from -5 C to +40 C.
Molecular Pathology	Cryostat	Leica Cryostat CM1850	Frozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.
Molecular Pathology	Histology/Tissue Processing - Balance	Mettler (PB303-S) semimicro balance	Mass range of 0.01 mg- 120 g.
Molecular Pathology	Histology/Tissue Processing - Histobath	Fisher Histobath 134	Prevents development of microscopic ice crystals and sample distortion.
Molecular Pathology	Histology/Tissue Processing - Microwave Oven	Amana (RFS18MPS) Microwave Oven	Tissue microwave fixation.
Molecular Pathology	Histology/Tissue Processing - Microwave Oven	GE Microwave oven (JE1460BF001)	Tissue microwave fixation.
Molecular Pathology	Imaging System - Camera	Polaroid camera	Instant recording of gels.
Molecular Pathology	Imaging System - Slide Scanner	Aperio ScanScope Slide Scanner CS2	Generates full color, high resolution digital images (cells, tissues and tissue arrays). 5 slide capacity. Image analysis software available. Stored and catalogued in searchable image data base.
Molecular Pathology	Incubator	Fisher Scientific Dry Bath Incubator	Precise temperature control for temperatures up to 130 C. Built in temperature sensing probe for improved temperature accuracy and control.
Molecular Pathology	Laser Capture Microdissection System	Arcturus Autopix LCM-1110	Automated laser capture microdissection of cells for RNA,DNA and proteins. Can isolate thousands of cells from FFPE tissues in minutes. 100-240V, 50-60Hz.
Molecular Pathology	Laser Capture Microdissection System	Arcturus XT Laser Capture Microdissection System	Automated IR and UV laser capture. Microdissection and cutting of cells for RNA, DNA and protein isolation. One modular platform with laser capture and cutting. Optional live-cell modules and camera. Any slide type. Wide range of objectives available, 2x-100x dry and 100x oil immersion.
Molecular Pathology	Microscope	Olympus Fluorescent Microscope BX41	Image Pro Imaging Software. Excitation available 330-385nm, 460-490nm, 510-550nm. Magnifications of 20,40, 100, 200 power. Both reflected light and sample fluorescence may be viewed through and recorded at the microscope.
Molecular Pathology	Microscope	Olympus BX41 General Use Microscope	Optical system: UIS2. Built in transmitted Koehler illuminator, 6V/30W bulb. Stage height movement by roller guide, stroke per rotation: 36.8mm. Full stroke range: 25mm. FN20, tube inclination 30 degrees. Stage size: 188 x 134 mm.
Molecular Pathology	Microtome	Finesse 325 Microtome	Used to prepare samples for observation under transmitted light or electron radiation. Microtome material varies depending on the specimen being sliced and the desired thickness of the sections cut.
Molecular Pathology	PCR Thermal Cycler	Stratagene Multiplex PCR System MX4000	Multiplex assays with up to 4 dyes. Single scanning fiber optic head. Four optic channels with user selected filters, use of a single PMT. Can use up to 5 targets in the same tube. 25 microliter sample size.
Molecular Pathology	pH Meter	Accumet pH meter	pH meter.
Molecular Pathology	Robotic Workstation - Barcoding	Ventana Discovery System	Automated staining module using bar code technology. Total automation in IHC staining of frozen/ paraffin embedded tissue, FISH and ISH using DNA, RNA or oligonucleotide probes on tissue or microarrays (gene expression).
Molecular Pathology	Spectrophotometer	Eppendorf BioPhotometer	50 microliter volumes. Automatic calculation of dilution factors. Measures wave lengths: 230, 260, 280, 340, 405, 490, 550, 595, 650 nm. Spectral bandwidth: 5nm at 230-340nm, 7nm at 405-650nm. Photometric random error +/- 0.002A at 0A, +/- 0.005A at 1A.
Molecular Pathology	Suspension Array System	Beecher Manual Tissue Microarrayer	Generates multiple specimen slides that can contain hundreds of individual tissues. Up to 100 tissue cores per paraffin block. Use for same histochemical and molecular detection techniques as with regular sections.
Molecular Pathology	Vacuum Oven	Napco Model 5831 vacuum oven	Capacity: 0.45 cu ft. Temp range: 35 C to 200 C. 30-in Hg vacuum capability. Vacuum bleed valves permit pulling of vacuums as high as 30 inches H. Full view observation window with latched door and built in safety to prevent thermal runaway.
Molecular Pathology	Waterbath	PolyScience refrigerated/heated (9106) circulating waterbath	Working temperatures from -40 C to +200 C. Temperature stabilities to ±0.005 C.
Mouse Transgenic and Gene Targeting Facility	Biological Safety Cabinet	NuAire Safety Cabinets Class 2 Type A/B3	Transgenics and gene targeting safety cabinets (2 units)
Mouse Transgenic and Gene Targeting Facility	Centrifuge	Thermo IEC Centra CL3R Refrigerated Centrifuge	Transgenics and gene targeting refrigerated centrifuge
Mouse Transgenic and Gene Targeting Facility	Electroporation System	Bio-Rad Gene Pulsar II	Transgenics and gene targeting electroporation system
Mouse Transgenic and Gene Targeting Facility	Freezer	Custom BioGenic Systems Liquid Nitrogen (LN2) Freezer	Transgenics and gene targeting liquid nitrogen freezer
Mouse Transgenic and Gene Targeting Facility	Freezer	Thermo Fisher Scientific -80 C	Transgenics and gene targeting -80 C freezer
Mouse Transgenic and Gene Targeting Facility	Freezer	Frigidaire -20 C Freezer	Transgenics and gene targeting freezer
Mouse Transgenic and Gene Targeting Facility	Gene Targeting	Service	Gene targeting services through transfection and microinjection of murine embryonic stem (ES) cells to produce germline knockout (KO) or knockin (KI) mice
Mouse Transgenic and Gene Targeting Facility	Incubator	NuAire CO2 water jacketed Incubators	Transgenics and gene targeting incubators (3 units)
Mouse Transgenic and Gene Targeting Facility	Microinjector	Eppendorf FemtoJet Microinjection System	Transgenics and gene targeting pronuclear injection system
Mouse Transgenic and Gene Targeting Facility	Micromanipulator	Eppendorf Transferman NK 2 Micromanipulators	Transgenics and gene targeting micromanipulators (2 units)
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon Eclipse TE200 Inverted Microscope	Transgenics and gene targeting microinjection microscope
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon Eclipse TS100 (cell culture scope)	Transgenics and gene targeting cell culture scope
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon SMZ1500 Zoom Stereomicroscopes	Transgenics and gene targeting dissecting microscopes (2 units)
Mouse Transgenic and Gene Targeting Facility	Microscope	Nikon SMZ800 Zoom Stereomicroscopes	Transgenics and gene targeting surgical microscope
Mouse Transgenic and Gene Targeting Facility	Technical Assistance - Karyotyping	Service	Service to determine euploidy of murine embryonic stem (ES) cells prior to microinjection
Mouse Transgenic and Gene Targeting Facility	Technical Assistance -Transgenics and Gene Targeting	Service	Service to provide custom services related to microinjection, ES cell culture, mouse surgery, or mouse reproduction. The core facility will provide services and/or training related to our capabilities that are not specifically covered by our service list. These services are available for an hourly fee. Examples include: production of MEFs (murine embryonic fibroblasts), polar body biopsy, reproductive surgery, blastomere injection, frozen embryo shipment, training
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Cryopreserved Mouse Embryo Recovery	Service	Service to thaw and implant previously cryopreserved mouse embryos
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Cryopreserved Mouse Embryo Storage	Service	Service to store cryopreserved mouse embryos in liquid nitrogen (LN2)
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Derivation of Mouse Embryonic Stem (ES) cell lines	Service	Service to produce embryonic stem (ES) cells from an existing mouse line key words: murine embryonic stem cells
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Embryonic Stem (ES) Cell Injection	Service	Service to produce chimeric mice for analysis through microinjection of murine embryonic stem (ES) cells into blastocyst stage embryos.
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mouse Colony Expansion	Service	Service to use superovulation and surgical implantation to produce large cohorts of age matched mice for experimentation or to quickly expand a mouse colony
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mouse Embryo Cryopreservation	Service	Service to cryopreserve valuable mouse lines for storage or shipment to other investigators.
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Mouse In vitro Fertilization (IVF)	Service	Service to perform in vitro fertilization of mouse embryos
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Rederivation of Mouse Lines	Service	Service to rederive mouse lines obtained from a source other than a Brown University approved vendor. Rederived mouse lines may be housed in any campus mouse facility.
Mouse Transgenic and Gene Targeting Facility	Transgenics and Gene Targeting - Transgenics	Service	Service to perform pronuclear microinjection of 0.5 dpc mouse embryos to produce transgenic founders on an FVB/N or C57/BL6 background. Custom backgrounds also available.
Mouse Transgenic and Gene Targeting Facility	Water Purification System	Milli Q Biocel	Transgenics and gene targeting water purification
Mouse Transgenic and Gene Targeting Facility	Waterbath	Thermo Scientific Precision 260 Circulating Waterbath	Transgenics and gene targeting circulating waterbath
Multiplex Facility	Behavioral Phenotyping - Four Lane Rotarod	Emitter-Columbus Rotamex 5 Controller	Used to assess motor coordination and balance
Multiplex Facility	Behavioral Phenotyping - Morris Water Maze	Fabricated in house	Opaque white pool with platform for behavioral swim test.
Multiplex Facility	Biospecimen Banking - Freezer	HHP Barcoding Instrument	Barcode samples for identification. File Pro software.
Multiplex Facility	Centrifuge	Beckman- Coulter Allegra 64R Refrigerated Centrifuge	For use with 50 mL conical tubes.
Multiplex Facility	Cryostat	Leica Cryostat	Frozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.
Multiplex Facility	Disrupter	Siegen Tissue Lyser	Disrupts multiple biological samples through high speed shaking in plastic tubes with steel, tungsten carbide, or glass beads. Up to 48 samples can be processed simultaneously.
Multiplex Facility	Imaging System	Applied Scientific Instrumentation MS-1000	XY stage designed to provide a high resolution, and highly repeatable, means of controlling the X and Y position of a microscope stage
Multiplex Facility	Imaging System - Camera	Olympus U-CMAD3 camera	Connected to Olympus Inverted CKX31 Fluorescent Microscope. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Multiplex Facility	Imaging System - Camera	Sony 3CCD Exwave HAD Digital Camera	Connected to Olympus BX60. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections.
Multiplex Facility	Imaging System - Camera	Stereologer 200	1/3" type DSP 3-CCD PAL color video camera with improved camera sensitivity (F8 at 2000 lx). Resolution of 800 TVL and a high S/N ratio of 61 dB.
Multiplex Facility	Microplate Reader	Molecular Dynamics M5 Spectracount	Cross talk (96-well): 3X 10-5, sensitivity: <20 attomol ATP per well, <0.2 firely luciferase per well, spectral range: 380-630 nm.
Multiplex Facility	Microplate Reader	Packard-Perkin Elmer Topcount	Analysis of cell proliferation, receptor binding assays, solid phase RIA/LIA, reporter gene assays, 51Cr release assays, HPLC fraction analysis, scintillation proximity assays, etc.
Multiplex Facility	Microplate Reader	Molecular Devices UV Max Microplate Reader	96-wellplate reader. Spectral range: 405-630 nm.
Multiplex Facility	Microscope	Olympus BX60	High-resolution digital pictures using conventional manual filter cubes or more versatile automated filter wheels, and can superimpose multi-color pictures
Multiplex Facility	Microscope	Olympus Inverted CKX31 Fluorescent Microscope	Inverted microscope with the capability of a fluorescence illuminator for GFP; documentation of images with digital imaging and video monitoring. Use for petri dishes, culture flasks, and multi-well plates.
Multiplex Facility	Microscope	Olympus Inverted Fluorescent microscope	FN22. 9mm stroke, coaxial coarse and fine focusing knobs. Long working distance universal condenser.
Multiplex Facility	PCR Thermal Cycler	Roche Lightcycler 4810	Exchangeable 96 or 384 multiwell plate format. Ideal for multiplexing and automated workflows. Provides various methods for gene detection, gene expression analysis, genetic variation analysis and array data validation.
Multiplex Facility	Robotic Workstation - DNA Extraction	QUIAGEN Biorobot EZ1	Fully automated purification of genomic DNA from human whole blood and viral nucleic acids from serum or plasma samples.
Multiplex Facility	Robotic Workstation - Pipetting	Eppendorf EpMotion 5070	Automated pipetting. Four deck positions can hold tips, reagent reservoirs, single tubes, tube racks, micro-plates, or PCR plates with up to 384 wells. Suited for serial dilutions, reagent distribution, transfer from tubes to plates and normalization.
Multiplex Facility	Robotic Workstation - Pipetting	Tecan Genesis 200 Robot	Automated robot for pipetting tasks. Two arms- the LiHa (liquid handler) and the RoMa (robot manipulator). LiHa- conductivity-sensing 8-channel pipetting arm dispenses volumes of 5-1000 µL; RoMa- manipulating arm picks up and moves objects on the workstation.
Multiplex Facility	Spectrophotometer	Thermo Scientific NanoDrop 2000	Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter.
Multiplex Facility	Suspension Array	Luminex Magpix	Reads magnetic bead–based immunoassays. Automated reading of 96-well plates (~60 min/plate). Multiplex analysis of up to 50 biomolecules in a single sample.
Multiplex Facility	Suspension Array	Bio-Rad BioPlex 100	Automated reading of 96-well plates, up to 9,600 data points in about 35 min. Multiplex analysis of up to 100 biomolecules in a single sample via suspension array.
Multiplex Facility	Suspension Array System	Bio-Rad Vacuum manifold	Vacuum purification platform for single 96-well plates or individual luer-ended spin columns. Compatible with Bio-Plex 200 suspension array system.
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 300 Avance	z-BBI probe, (least sensitivte 1H and indirect detection to all broadband nuclei)
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 600 Avance III HD Ascend	z-BBFO probe for all nuclei (most sensitive for all nuclei)
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 400 Avance III Ultra-Shield	z-TXI probe, (2nd best sensitivity for 1H and indirect detection on 13C/15N)
NMR Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 400 Avance Ultra-Shield	z-BBO probe, (2nd best sensitivity for broadband nuclei)
PC - Albertus Magnus Hall Labs	Environmental Chamber Contact: Maia Bailey	Percival Scientific	2 units
PC - Albertus Magnus Hall Labs	Environmental Chamber Contact: Maia Bailey	Percival Scientific, AR-22L Growth Chamber	For Arabidopsis
PC - Albertus Magnus Hall Labs	Imaging - Camera Contact: Pat Ewanchuk	Fastec HiSpec1, Low-Light High-Speed Camera	Innovative Low-Light High-Speed Camera. Monochrome with 2GB Memory, C-Mount, includes ImageBLITZ Auto Trigger, Burst Trigger Mode, Multi- Sequence Record Mode (1280 x 1024 at 506fps) 2 Units
PC - Albertus Magnus Hall Labs	Microscope - Electron Contact: Joe DeGiorgis	Philips EM-300 Transmission Electron Microscope (TEM)	Transmission electron microscopy
PC - Albertus Magnus Hall Labs	Laboratory - Prep Lab Contact: Joe DeGiorgis	Electron Microscopy Prep Lab	Laboratory space for preparing samples for electron microscopy
PC - Albertus Magnus Hall Labs	Microscope - Electron Contact: Joe DeGiorgis	Amray-1000 Scanning Electron Microscope (SEM)	Scanning Electron Microscope equipped with EDEX for elemental analysis and a digital imaging system, a Zeiss Axiophot equipped for bright field, dark field, DIC and fluorescence microscopy with a digital imaging system
PC - Albertus Magnus Hall Labs	Microtome Contact: Joe DeGiorgis	Porter-Blum MT-2B Ultramicrotome	Porter-Blum MT-2B UltraMicrotomes, 2 Units
PC - Albertus Magnus Hall Labs	Aquatic System Contact: Pat Ewanchuk	Aquatic Habitats Glass Tank System and Life Support Controller	Glass tank system and life support controller with low water level protection (18-10 gallon tanks)
PC - Hickey Hall Labs	DNA Sequencer Contact: Elisabeth Arevalo	ABI Prism 3100 Genetic Analyzer	Used for DNA sequencing and fragment analysis. The ABI PRISM 3100 Genetic Analyzer is an automated capillary electrophoresis system that can separate, detect, and analyze up to 16 capillaries of fluorescently labeled DNA fragments in one run.
PC - Hickey Hall Labs	PCR Thermal Cycler Contact: Charles Toth	Stratagene Mx3000p Real-time PCR Thermal Cycler	This instrument is available for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Agilent’s qPCR software, MxPro, provides users with an intuitive interface, quick experiment design, powerful data analysis and easy report generation
PC - Hickey Hall Labs	Fluorescence Activated Cell Sorter (FACS) Contact: Charles Toth	Flow Cytometer- Accuri C6	The BD Accuri C6 is a personal flow cytometer that is easy to use, simple to maintain, and affordable.
PC - Hickey Hall Labs	Cold Room Contact: Charles Toth	Walk-In Cold Room
PC - Hickey Hall Labs	Analyzer - Cell Metabolism Contact: Marla Tipping	Seahorse Biosciencies, XFe Extracellular Flux Analyzers, XFe96	Platform for metabolic assays that simultaneously measures the two major energy producing pathways of the cell - mitochondrial respiration and glycolysis - in a microplate, in real-time.
PC - Hickey Hall Labs	Laboratory - Tissue Culture Contact: Charles Toth	Tissue Culture Laboratory	Space and instrumentation for tissue culture preparation
PC - Hickey Hall Labs	Imaging System - Gel Imager Contact: Yinsheng Wan	Licor Odyssey IR (Infrared) Imaging System	Instrumentation for quantitating western blots.
PC - Hickey Hall Labs	Fluorescence Activated Cell Sorter (FACS) Contact: Nicanor Austriaco	Cellometer Vision Image Cytometry	The Vision CBA System combines the simplicity of image cytometry with the power of flow analysis software to offer user-friendly cell-based assays
PC - Hickey Hall Labs	Spectrophotometer Contact: Charles Toth	Thermo Scientific NanoDrop	UV/VIS
PC - Sowa Hall Labs	Microscope Contact: Joe DeGiorgis	Zeiss LMS 700 Flexible Confocal Microscope	Performs fluorescence measurements, creates optical sections of samples and combines them into 3D image stacks.
Proteomics Core	Bioanalyzer	Agilent Bioanalyzer 2100	Microfluidics platform (electrophoresis and flow cytometry) for sizing, quantification, and QC of DNA, RNA, proteins, and cells. Sample size= 1-4 microliters.
Proteomics Core	Bioinformatics Analysis - HD Examiner DXMS analysis software	Software: HD Examiner DXMS Analysis	Software to analyze peptide search results from SEQUEST HTML, Mascot XML, Proteome Discoverer .xls, pepXML, or generic tabular data. Both low- and high-resolution MS data.
Proteomics Core	Bioinformatics Analysis - MASCOT	Software: Matrix Science MASCOT Search Engine	Software for MS data analysis through statistical evaluation of matches between observed and projected peptide fragments.
Proteomics Core	Bioinformatics Analysis - ProteoIQ	Software: NuSep ProteoIQ Mass Spec Data Analysis	Software for post-analysis of MASCOT results. Protein and peptide probabilities generated and protein relative quantitation is performed by spectral counting. Normalized and with standard deviations.
Proteomics Core	Bioinformatics Analysis - Workstation	Hardware: HP HPZ 800 Workstation	Software (2 workstations available) used in conjunction with ProteoIQ, DXMS, MASCOT analysis.
Proteomics Core	Gel Imager	Bio-Rad Molecular Imager VersaDoc	Quantitative digital imaging system for single or multi-color images. Includes multiplexed samples (1-D or 2-D gels), chemiluminescent and chemifluorescent blots, and microplates.
Proteomics Core	High Performance Liquid Chromatography (HPLC)	Bio-Rad DuoFlow Biologic HPLC	Medium-pressure chromatography system. 100/120 V, F10 workstation, mixer, AVR7-3 valve, UV detector with flow cell and filters. Flow rate= 0.01–10 ml/min.
Proteomics Core	High Performance Liquid Chromatography (HPLC)	Transgenomic Wave DHPLC System	Detect mutations/ polymorphisms by Denaturing High Performance Liquid Chromatography (DHPLC). Uses SURVEYOR nuclease cleavage. Identifies single nucleotide polymorphisms (SNPs) or small insertions/ deletions.
Proteomics Core	High Performance Liquid Chromatography (HPLC)	Dionex UltiMate3000 Nano HPLC	Single gradient and x2 dual configurations. Eluted directly into MS. Min detection= fmole; Min flow rate= 20 nL/min; Max pressure = 800 bar.
Proteomics Core	Liquid Chromatography- Mass Spectrometer (LC-MS)	Thermo Scientific Q Exactive Mass Spectrometer	Benchtop LC-MS/MS. Combination of high-performance quadrupole with high resolution, accurate-mass (HR/AM) Orbitrap. Max resolving power= 140,000; max scan speed= 12Hz, Intra-scan dynamic range > 5000:, Quadrupole mass filter.
Proteomics Core	Mass Spectrometer	AB SCIEX QSTAR XL Mass Spectrometer	Identification and analysis of protein structure/conformational change by deuterium exchange mass spectrometry (DXMS). LC/MS/MS- Ionization by MALDI or ESI after HPLC (Dionex) and analyzed by quadrupole and TOF.
Proteomics Core	Mass Spectrometer	Brucker UltrafleXtreme: Imaging Mass Spectrometry	MALDI-IMS for tissue imaging, intact proteins analysis, protein spatial distribution, glycoproteomics, or biologics (1-2000 Hz repetition rates) of non-injured vs. injured tissues. MALDI/TOF/TOF analysis for proteomic profiling. Minimum diameter = 10 microns.
Proteomics Core	Robotic Workstation -Liquid Handler	Perkin Elmer JANUS Automated Workstation	Automated Sterile Liquid Handler. 2 arm system, with 4- or 8-tip arm plus a 96/384 MDT arm. Arms include 4-tip or 8-tip dispense arms for transfer from tubes to vials to plates.
Proteomics Core	Spectrophotometer	Amersham Biosciences UV/Visible Spectrophotometer Ultrospec 1100	Wavelength range: 200–900 nm. Spectral bandwidth: 5 nm Wavelength accuracy ± 2 nm. Wavelength reproducibility: ± 0.5 nm.
Proteomics Core	Spectrophotometer	Thermo Scientific NanoDrop 2000	Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter.
Proteomics Core	Suspension Array System	Bruker ImagePrep matrix sprayer	Matrix deposition device for MALDI Imaging. Average droplet size ? 20 microns, all droplet dia. are < 50 microns. Lateral resolution of 50 microns in tissue.
Proteomics Core	Suspension Array System	LC Packings ProBot LC/MALDI spotter	Nano-LC/MALDI-MS interface. Robotic system for MALDI spotting/fraction collection. On-line collection of nL- and microliter-fractions from nano/capillary LC systems on sample carriers (MALDI targets, PVDF membranes, 96, 384, or 1536 well plates, or microchip structures). Two well plate capacity. Dual-collection mode for fraction splitting over two different sample carriers.
Proteomics Core	Technical Assistance - 1D SDS PAGE Coomasie	Service	Service to provide 1D gel (SDS-PAGE) Coomasie Staining.
Proteomics Core	Technical Assistance - 1D SDS PAGE Silver Stain	Service	Service to provide 1D gel (SDS-PAGE) Silver Stain MS compatible.
Proteomics Core	Technical Assistance - Bioanalyzer	Service	Service to provide Agilent Bioanalyzer (Protein 80).
Proteomics Core	Technical Assistance - Bioanalyzer	Service	Service to provide Service to provide Agilent Bioanalyzer (Protein 250).
Proteomics Core	Technical Assistance - Bioanalyzer	Service	Service to provide Service to provide Agilent Bioanalyzer (Protein 230).
Proteomics Core	Technical Assistance - Deuterium Exchange MS (DXMS)	Service	Service to provide Deuterium Exchange MS (DXMS)- Data analysis and interpretation
Proteomics Core	Technical Assistance - Deuterium Exchange MS (DXMS)	Service	Service to provide Deuterium Exchange MS (DXMS)- Digestion Optimization (includes duplicates)
Proteomics Core	Technical Assistance - Deuterium Exchange MS (DXMS)	Service	Service to provide Deuterium Exchange MS (DXMS)- Experimental Setup
Proteomics Core	Technical Assistance - Deuterium Exchange MS (DXMS)	Service	Service to provide Deuterium Exchange MS (DXMS)- On-exchange time course experiment (includes duplicates)
Proteomics Core	Technical Assistance - Deuterium Exchange MS (DXMS)	Service	Service to provide Deuterium Exchange MS (DXMS)- Triplicates
Proteomics Core	Technical Assistance - Gel Imaging	Service	Service to provide Gel imaging by VersaDoc.
Proteomics Core	Technical Assistance - MALDI Imaging MS	Service	Service to provide MALDI Imaging MS.
Proteomics Core	Technical Assistance - Mass Spectrometry	Service	Service to provide ImagingMass Spectrometry Data Analysis.
Proteomics Core	Technical Assistance - Protein Determination	Service	Service to provide Protein Determination (BCA assay).
Proteomics Core	Technical Assistance - Protein Extraction	Service	Service to provide ReadyPrep Protein Extraction Kit (Sequential Extraction).
Proteomics Core	Technical Assistance - Protein Extraction	Service	Service to provide ReadyPrep Protein Extraction Kit (Total Protein).
Proteomics Core	Technical Assistance - Protein In-Gel Digestion	Service	Service to provide In-gel digestion LC/MS analysis and protein database search.
Proteomics Core	Technical Assistance - Protein In-Solution Digestion	Service	Service to provide In-solution digestion LC/MS analysis and protein database search.
Proteomics Core	Technical Assistance - Protein Quantification	Service	Service to provide Data interpretation and protein quantification.
Proteomics Core	Technical Assistance - Protein Sample Clean-up	Service	Service to provide ReadyPrep 2D Cleanup Kit.
Proteomics Core	Technical Assistance - Proteomics Project Consultation	Service	Service to provide Project consultation with the Director of Proteomics – Subsequent Consultation
Proteomics Core	Technical Assistance - Proteomics Project Consultation	Service	Service to provide Project consultation with the Director of Proteomics – Initial Consultation
Proteomics Core	Technical Assistance - WAVE DNA	Service	Service to provide WAVE (DNA).
Proteomics Core	Technical Assistance - WAVE PCR	Service	Service to provide WAVE (PCR product).
Proteomics Core	Technical Assistance - WAVE Tissue	Service	Service to provide WAVE (tissue).
Proteomics Facility	Bioinformatics Analysis - MASCOT	Software: Matrix Science MASCOT Search Engine	Software for protein identification, characterization and quantitation (v.2.4.1)
Proteomics Facility	Bioinformatics Analysis - PEAKS Studio	Software: Bioinformatics Solutions Inc. PEAKS Studio	Software for de novo sequencing and database searching (v.6.0)
Proteomics Facility	Bioinformatics Analysis - ProSight PC	Software: Thermo Scientific ProSight PC	Software for "top-down" proteomics analysis (v.2.0)
Proteomics Facility	Bioinformatics Analysis - ProteoIQ	Software: NuSep ProteoIQ Mass Spec Data Analysis	Software for mass spectrometry proteomic analysis (v.2.61)
Proteomics Facility	Bioinformatics Analysis - Proteome Discoverer	Software: Thermo Scientific Proteome Discoverer	Software for database searching and protein quantitation (v.1.3)
Proteomics Facility	Calorimeter	Microcal Isothermal Titration 200 (ITC)	Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
Proteomics Facility	Calorimeter	Microcal VP Differential Scanning (DSC)	Measurement of heat changes that occur in biomolecules during controlled increase or decrease in temperature.
Proteomics Facility	Fermenter	Infors Minifor	A bench-top (1-5 L) laboratory fermenter and bioreactor for bacteria and yeast.
Proteomics Facility	Fluorometer - Spectrofluorometer	Horiba Jobin Yvon FluoroMax-4	Fluorescence detection. A heated cell allows temperature studies.
Proteomics Facility	High Performance Liquid Chromatography - Ultra High (UHPLC)	AB SCIEX Eksigent nanoLC-Ultra 2D+ UHPLC	Isocratic low flow rates of 1-20 microliter/min and dual nanoflow pumps for 50-1000 nL/min. A novel pumping system eliminates the need for flow splitting, providing excellent run-to-run reproducibility. It serves as the "front end" for nanoflow LC/MS.
Proteomics Facility	High Performance Liquid Chromatography (HPLC)	Agilent 1200 HPLC System	High performance liquid chromatography system with quaternary pump and thermostatted autosampler serves as the "front end" for nanoflow LC/MS.
Proteomics Facility	High Performance Liquid Chromatography (HPLC)	Agilent 1200 HPLC System	High performance liquid chromatography system with: quaternary pump, thermostatted autosampler, thermostatted fraction collector, and a multi-wavelength UV/Vis detector. It can be used for analytical detection of biomolecules and/or their purification.
Proteomics Facility	Liquid Chromatography System	GE Healthcare AktaPrime Plus	The ÄKTA Prime Plus is a low pressure chromatography system that performs simple purifications of tagged and untagged proteins.
Proteomics Facility	Mass Spectrometer	Thermo Scientific LTQ Orbitrap Velos	Peptide/protein identification in complex samples, molecular weight determination of intact proteins, post translational modification analysis (PTM), improved quantitation of peptides in label-free, SILAC, iTRAQ or TMT experiments.
Proteomics Facility	Spectrophotometer	JASCO J-815 Circular Dichroism (CD) Spectrometer	Protein folding studies, Protein conformational studies, DNA/RNA interactions, Enzyme kinetics, Purity testing of optically active substances, quantitative analysis of pharmaceuticals, natural products chemistry, biochemistry and macromolecules, rapid scanning (time resolved) experiments. Peltier device for temperature studies.
Proteomics Facility	Spectrophotometer	Thermo Scientific NanoDrop 8000	A full spectral microvolume (microliter) UV-Vis analysis spectrophotometer for measuring DNA, RNA, and protein of 8 samples simultaneously.
Proteomics Facility	Surface Plasmon Resonance (SPR) Sensor	General Electric Healthcare Biosciencees Biacore X 100	Label-free protein interaction analysis provides unique and comprehensive data on the interactions between biomolecules. Performs quantitative kinetic analysis (rate constants), quantitative determination of affinity constants, determination of binding specificity (yes/no), and concentration analysis.
Proteomics Facility	Technical Assistance - Protein Determination	Service	Service to determine protein concentration using Life Technologies QuBit, Thermo Scientific Pierce Protein 660, or Thermo Scientific Micro BCA
Proteomics Facility	Technical Assistance - Protein In-Gel Digestion	Service	Service to destain, reduce and alkylate, enzyme digest and extract peptides from a gel
Proteomics Facility	Technical Assistance - Protein In-Solution Digestion	Service	Service to denature, reduce and alkylate and enzyme digest proteins in solution
Proteomics Facility	Technical Assistance - Protein Sample Clean-up	Service	Service to remove protein solution contaminants and/or concentrate protein samples using Bio-Rad ReadyPrep 2D,Thermo C18 Spin, Millipore ZipTip
Proteomics Facility	Technical Assistance - Proteomics Project Consultation	Service	Service to provide Proteomics Technical Assistance
Proteomics Facility	Technical Assistance - Proteomics Training	Service	Service to provide Proteomics Training
Research Facility	Autoclave	Tuttnauer	Equipment: consumable sterilization
Research Facility	Behavioral Phenotyping - Eye Tracking System	Tobii	Used to track eye movement
Research Facility	Bioanalyzer	Agilent Bioanalyzer	DNA size & quantification (quality check for downstream analyses, i.e. next gen sequencing)
Research Facility	Capillary Electrophoresis	Applied Biosystems	Analyze fragment length polymorphisms (96/384 format) (2)
Research Facility	Centrifuge	Eppendorf Refrigerated Centrifuge	Alcohol precipitation
Research Facility	Centrifuge	Eppendorf	For centrifuging 96/384 plates
Research Facility	DNA Sequencer	Ion Torrent/Life Technologies Personal Genome Machine	Next Generation Sequencer
Research Facility	Mass Spectrometer	Sequenom	high throughput SNP genotyping, epigenetics
Research Facility	Microarray Scanner	Illumina HiScan	Whole-genome genotyping, gene expression analysis, methylation analysis
Research Facility	Microplate Reader	BioTek	DNA quantification
Research Facility	Microplate Reader	Fluidigm End Point Reader	High throughput SNP genotyping
Research Facility	PCR Thermal Cycler	Applied Biosystems	384 well DNA amplification for downstream analysis (i.e. sequenom processes) (2 units)
Research Facility	PCR Thermal Cycler	Applied Biosystems	96 well DNA amplification for downstream analysis (i.e. fragment length polymorphisms)(2 units)
Research Facility	PCR Thermal Cycler	Applied Biosystems Real Time PCR	Analyze single nucleotide polymorphisms (single locus)
Research Facility	PCR Thermal Cycler	Applied Biosystems Real Time PCR	Analyze single nucleotide polymorphisms (single locus)
Research Facility	Robotic Workstation - DNA Extraction	Chemagen/Perkin Elmer Magnetic Separation Module	DNA extraction from blood & saliva
Research Facility	Robotic Workstation - Liquid Handler	Sequenom Liquid Handler	Transfers PCR chemistries to samples (96/384 format)
Research Facility	Robotic Workstation - Liquid Handler	Sequenom Nanodispenser	Dispenses PCR product to Sequenom chip
Research Facility	Robotic Workstation - Sample Preparation	Iontorrent/Life Technologies Enrichment System	Simplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.
Research Facility	Robotic Workstation - Sample Preparation	Iontorrent/Life Technologies One Touch	Simplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.
Research Facility	Robotic Workstation - Sample Processing	Thermo Scientific Cap-it-All	Caps tubes to the optimal torque to maintain sample integrity and provide a hands free method to capping and decapping tubes quickly and easily.
Research Facility	Robotic Workstation -Liquid Handler	Beckman Coulter Lab Automation Workstation	Automated liquid handler
Research Facility	Spectrophotometer	Thermo Scientific NanoDrop	DNA quantification
Rhode Island BioBank	Bioinformatics Analysis - Freezerworks	Software: Freezerworks	Sample management software
Rhode Island BioBank	Biospecimen Banking	Service	Service to store biospecimens at -80 degrees, 4 degrees and in liquid nitrogen. All equipment is connected to back–up generator power and monitored 24/7 by a Rees alarm system.
Rhode Island BioBank	Biospecimen Banking - Freezer System	Taylor Wharton LABS 40K Liquid Nitrogen Storage System	Liquid nitrogen storage system connected to back–up generator power and monitored 24/7 by a Rees alarm system
Rhode Island BioBank	Robotic Workstation - Sample Preparation	Qiagen QiaCube	DNA, RNA or Protein Purification
Rhode Island Nuclear Science Center	Reactor, Research and Test Contact: Jeff Davis	2 Mega-Watt, light water cooled, pool type reactor	Neutron and gamma irradiation, as well as analysis
RIC - Fogarty Life Sciences Labs	Knifemaker Contact: Breea Govenar	LKB 7800 Knifemaker	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Microtome Contact: Breea Govenar	Leica RM2165 Motorized Rotary Microtome	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Microtome Contact: Breea Govenar	TBS Microtome plus Cryostat	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	American Optical Series 10 Fluorescence Microstart	Microscopy course
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Nikon E600 Epifluorescence with DIC/Phase and digital camera	Research
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus CKS41 Inverted Microscope	Tissue culture general use
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus Compound Light Microscope	General use
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus FluoView 1000 Laser Scanning Confocal Microscope	Research and Microscopy course
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Olympus Inverted Epifluorescence Microscope with digital camera	Tissue culture/Research
RIC - Fogarty Life Sciences Labs	Microscope Contact: Breea Govenar	Zeiss SteREO discovery V8 Microscope with Digital Camera	Research
RIC - Fogarty Life Sciences Labs	Wet Lab / Aquarium room Contact: Breea Govenar	Aquaria and related equipment	Research
RIC - Fogarty Life Sciences Labs	Autoclave Contact: Breea Govenar	Autoclave	Microbiology/Research
RIC - Fogarty Life Sciences Labs	Biological Safety Cabinet Contact: Breea Govenar	Labconco class II Biological Safety Cabinet	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Biological Safety Cabinet Contact: Breea Govenar	Sterile laminar flow hood	Microbiology prep
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Eppendorf 5810R Refrigerated Centrifuge	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Sorvall Discovery M120SE Mini Ultracentrifuge	Research/Cell fractionation
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Sorvall Superspeed RC2 Centrifuge	General use
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Sorvall Superspeed RC5 Plus Centrifuge	Research
RIC - Fogarty Life Sciences Labs	Centrifuge Contact: Breea Govenar	Thermo IEC Centra CL3R Refrigerated Centrifuge	Genetics and Cell & Molec courses
RIC - Fogarty Life Sciences Labs	Cold Room Contact: Breea Govenar	Walk-In Cold Room	Large cold room for experimentation and storage
RIC - Fogarty Life Sciences Labs	Dishwasher Contact: Breea Govenar	Dishwasher	Microbiology/Research
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	French Pressure Cell Press	Research
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	Polytron Tissue Grinder	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	Sonicator	General use and research
RIC - Fogarty Life Sciences Labs	Disrupter Contact: Breea Govenar	Sonicator with cup	Research and graduate courses
RIC - Fogarty Life Sciences Labs	Electroporation System Contact: Breea Govenar	BioRad Micropulser Electroporator	Research
RIC - Fogarty Life Sciences Labs	Freeze Dryer Contact: Breea Govenar	ATMO VAC 5009 freeze dryer	Slide/Sample Preparation
RIC - Fogarty Life Sciences Labs	Freezer Contact: Breea Govenar	Thermolyne Liquid Nitrogen cryogenic storage system	Cell storage
RIC - Fogarty Life Sciences Labs	Freezer Contact: Breea Govenar	Ultralow Freezer	Used for freezing biological samples, 6 units
RIC - Fogarty Life Sciences Labs	Gel Imager Contact: Breea Govenar	InGenius Syngene Gel Documentation System	Research
RIC - Fogarty Life Sciences Labs	Ice Machine Contact: Breea Govenar	Ice Machine	General use
RIC - Fogarty Life Sciences Labs	Imaging System - Dark Room Contact: Breea Govenar	Imaging System - Dark Room	Gel imaging and analysis
RIC - Fogarty Life Sciences Labs	Incubator Contact: Breea Govenar	Non CO2 Incubator	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Incubator Contact: Breea Govenar	Thermo CO2 Incubators	Used for tissue culture, 2 units
RIC - Fogarty Life Sciences Labs	Incubator Contact: Breea Govenar	Refrigerated Incubator	Used for tissue culture
RIC - Fogarty Life Sciences Labs	Laboratory - Tissue Culture Contact: Breea Govenar	Tissue Culture Room	A room outfitted with tissue culture instrumentation
RIC - Fogarty Life Sciences Labs	Microplate Reader Contact: Breea Govenar	Lenovo Automated Plate Reader	Research
RIC - Fogarty Life Sciences Labs	Microplate Reader Contact: Breea Govenar	Thermo Labsystems Multiskan MMCC/340 plate reader	Research
RIC - Fogarty Life Sciences Labs	Oven Contact: Breea Govenar	Drying Oven	General use
RIC - Fogarty Life Sciences Labs	PCR Thermal Cycler Contact: Breea Govenar	BioRad IQS Real time PCR thermocycler	Research
RIC - Fogarty Life Sciences Labs	PCR Thermal Cycler Contact: Breea Govenar	Eppendorf Gradient Mastercycler	PCR instrumentation, 2 units
RIC - Fogarty Life Sciences Labs	Shakers Contact: Breea Govenar	Incubator/Shakers	Multiple units
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	BioRad SmartSpec Plus	Research
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Eppendorf Biophotometer	Gectrophotometerseral use
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Spectronic 21 D UV/VIS	Research
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Therm Spectronic Genesys UV/VIS Scanning	Research, 6 units
RIC - Fogarty Life Sciences Labs	Spectrophotometer Contact: Breea Govenar	Thermo Scientific NanoDrop ND-1000	UV/VIS, 2 units
RIC - Fogarty Life Sciences Labs	Water Purification System Contact: Breea Govenar	Barnstead Still Water Purifier	General use for teaching labs
RIC - Fogarty Life Sciences Labs	Water Purification System Contact: Breea Govenar	Millipore DirectQ (X2)	Tissue culture
RIC - Fogarty Life Sciences Labs	Water Purification System Contact: Breea Govenar	Millipore NanoPure Diamond	2nd floor research use
RIC - Fogarty Life Sciences Labs	Imaging System - X-ray Film Contact: Breea Govenar	X-ray film processor	Blot imaging
RISD Media Resources	Imaging System - Audio\|Visual	Kodak zi 10 Video Camera (8 units)	Portable HD pocket camcorder, batteries, adaptor cables, cases, accessories
RISD Media Resources	Imaging System - Audio\|Visual	H4N ZOOM Audio Recorder (5 Units)	High performance portable digital audio recorder, batteries, adaptor cables, cases, accessories
RISD Media Resources	Imaging System - Audio\|Visual	ZOOM Q3 Video Camera (7 Units)	Portable palm camcorder, batteries, adaptor cables, cases, accessories
RISD Media Resources	Imaging System - Audio\|Visual	EPS-SonyPMWEX1R-01 (2 Units)	High performance HD CMOS solid state video camera, batteries, portable hard drive, adaptor cables, cases, studio lighting equipment, accessories
RISD Nature Lab	Aquatic System	Marine Ecological Habitats Closed-System Aquarium	560 L closed-system recirculating marine holding tanks with temperature control (2 units)
RISD Nature Lab	Microscope	Phenom G2Pro Scanning Electron Microscope (SEM)	Desktop Scanning Electron Microscope with ProSuite tiling and remote access software
RISD Nature Lab	Microscope	Olympus SZX16 Stereomicroscope	Light microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging software
RISD Nature Lab	Microscope	Olympus IX51 Inverted Fluorescent/Brightfield Microscope	Fluorescence/brightfield microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging software
RISD Nature Lab	Microscope	Olympus CH30 Upright Light Microscope	Upright light microscope with 3.3 MP Jenoptik digital camera, Canon Vixia HFS20 HD video camera, computer workstation, graphics and imaging software (2 units)
RISD Nature Lab	Microscope	Olympus SZ40 Stereomicroscope	Light microscope with 3.3 MP Jenoptik digital camera, computer workstation, graphics and imaging software
RISD Nature Lab	Microscope	Olympus SZ30 Stereomicroscope	Light microscope with LED illuminator (24 units)
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping	Service	A high-throughput behavioral testing facility that integrates high-level computer vision, computer learning, and custom built hardware solutions with behavioral testing to automate tracking, cataloging, and analysis of both home cage behavior and standard rodent testing paradigms to characterize preclinical models of disorders, test novel pharmacological and genetic rescue strategies in rodent models.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - 4x Operant Chambers	Med Associates	Can be used to train mice on operant tasks (equipped with water dipper system) for reinforcement learning, as well as grid floor and speaker system for fear conditioning experiments
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - 2x Open Field	Fabricated in house	Used to monitor activity in novel settings and to assay anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - 3-chamber Social Preference	Fabricated in house	Used to assess a mouse preference for being in close proximity to another mouse.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Barnes Maze	Fabricated in house	Used to assess spatial learning and memory in rodent models.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Cold Swim Stress	Fabricated in house	Used to monitor anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Cylinder Test	Fabricated in house	Used to assess motor coordination and balance
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Early Life Drug Exposure	Fabricated in house	Used to assess the impact of pharmacological agents on cognitive, motor, and affective development.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Early Life Stress (Maternal Bedding Restriction)	Fabricated in house	Used to induce later development of anxiety and depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Early Life Stress (Variable shock)	Fabricated in house	Used to assess elevated levels of anxiety and depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Elevated Zero Maze	Fabricated in house	Used to monitor rodent anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Estrous Cycling (Vaginal Cytology)	Fabricated in house	Used to assess stage of estrous cycle of rodent models.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Exercise Induced Anorexia	Fabricated in house	Use of running and food restriction to induce lower levels of body fat and food consumption
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Five Lane Forced Treadmill	Columbus Instruments	Used to induce exercise stress to assess motor fatigue and locomotor abilities.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Five Lane Rotarod	Med Associates	Used to assess motor pattern learning and coordination.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Flurothyl Induced Seizures	Fabricated in house	Used to assess monitored induction of tonic and clonic seizures
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Forced Swim	Fabricated in house	Used to assess depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Formalin Test (Pain)	Fabricated in house	Used to assess chronic pain
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Grip Strength Meter	Columbus Instruments	Used to assess grip strength
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Hargreaves Method to Assess Allodinia	IITC	Used to assess thermal sensitivity and efficacy of analgesics to decease pain sensitivity
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Homecage Monitoring	Fabricated in house	Used for long term monitoring of homecage activity of mice. Can provide longitudinal data regarding (eating, resting, grooming, drinking, walking, climbing, rearing, and micromovements). Will be used as a proxy for other more acute tests.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Homecage Wheel Running	Lafayette Instruments	Used to assess general levels of locomotor activity and as a proxy to measure changes in circadian rhythms.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Hot Plate Analgesia Meter	Basille	Used to assess thermal sensitivity.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Light /Dark Box	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Marble Burying	Fabricated in house	Used to assess anxiety-like behavior and OCD-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Maternal Deprivation	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Maternal Separation	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Morris Water Maze	Fabricated in house	Used to assess spatial learning and memory
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Non-invasive Blood Pressure Monitoring	Columbus Instruments	Tail cuff and apparatus for repeated measurement of blood pressure in mice.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novel Object Identity	Fabricated in house	Used to assess working memory
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novel Object Location	Fabricated in house	Used to assess spatial learning and memory
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novelty Induced Hypophagia	Fabricated in house	Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Novelty Suppressed Feeding	Fabricated in house	Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Olfactory Cross-habituation	Fabricated in house	Used to assess olfactory acuity.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Olfactory Perceptual Learning	Fabricated in house	Used to assess ability to learn to discriminate closely related odor pairs.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Predator Odor Stress	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Resident Intruder Aggression	Fabricated in house	Used to assess propensity for aggressive behavior.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Restraint Stress	Fabricated in house	Used to assess hippocampal atrophy and increased anxiety and depressive-like behavior.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Righting Reflex	Fabricated in house	Used to assess coordination and ability to right from a prone position.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Shock Threshold	Fabricated in house	Used to assess changes in pain sensitivity
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Single Lane Rotarod	Med Associates	Used to assess motor pattern learning and coordination.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Social Defeat Stress	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Social Disruption Stress	Fabricated in house	Used to assess anxiety-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Social Odor Discrimination	Fabricated in house	Used to assess ability to detect and discriminate between odorants of conspecifics.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Sucrose Preference	Fabricated in house	Used to asses depressive-like behavior (anhedonia).
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Tail Suspension	Fabricated in house	Method to assess depressive-like behavior
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Visual Cliff	Fabricated in house	Used to assess depth perception and avoidance learning during visual development.
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - von Frey Filaments	Bioseb	Used to assess tactile sensitivity
Rodent Behavioral Phenotyping Facility	Behavioral Phenotyping - Wire-hang	Fabricated in house	Used to assess animals strength and endurance.
RWU Lab Spaces	Fluorescence Activated Cell Sorter (FACS) Contact: Marcie Marston	Millipore Guava easyCyte Flow Cytometer	Flow Cytometer
RWU Lab Spaces	Gas Chromatograph - Mass Spectrometer (GC - MS) Contact: Nancy Breen	Agilent 5890 Gas Chromatograph - Mass Spectrometer (GC - MS) wth Mass Selective Detetor (MSD)	GC MS for teaching and research
RWU Lab Spaces	High Performance Liquid Chromatography (HPLC) Contact: Nancy Breen	Waters 2695 High Performance Liquid Chromatograph-MS / ZQ Micromass Mass Spectrometer	LC - MS for teaching and research
RWU Lab Spaces	Gas Chromatograph Contact: Nancy Breen	Agilent 7890 Gas Chromatography with DB-23 column	GC for fatty acid analysis
Structural Biology Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 500 Avance II, with TCI cryoprobe	An NMR spectrometer optimized for studying proteins in solution. This spectrometer is most useful for tracking binding interactions, measuring dynamic properties of proteins, and assigning protein resonances. Capable of using 5 mm and 3 mm tubes. Also suitable for proton NMR of small molecules and natural products.
Structural Biology Facility	Nuclear Magnetic Resonance (NMR) Spectrometer	Bruker 850 MHz Avance III HD, with TCI cryoprobe	An NMR spectrometer optimized for studying proteins in solution. This spectrometer is ideal for determining protein structures and measuring protein dynamics. Its extreme sensitivity allows studies on otherwise intractable samples. Capable of using 5 mm, 3 mm, and shaped NMR tubes. Also suitable for proton NMR of small molecules and natural products
Structural Biology Facility	X-ray Diffraction System	Rigaku ACTOR robot and Saturn 944 HG CCD
Structural Biology Facility	X-ray Scattering System	Rigaku BioSAXS 1000 with Pilatus 100K detector	An instrument useful for collecting small- and wide- angle X-ray scattering data for proteins in aqueous solution. This instrument is useful for assessing molecular size and shape. Temperature controller available.
Tissue Banking Core	Bioinformatics Analysis - Database	Software: Database developed in Filemaker Pro	Database and tissue inventory management on a Dell computer workstation
Tissue Banking Core	Biospecimen Banking - Biosafety Cabinet	Dissecting hood	Hood dedicated to sterile tissue cutting with biohazard protection.
Tissue Banking Core	Biospecimen Banking - Freezer System	Forma 195878 LN2 backup for bank freezers	Systems inject liquid LN2 into cabinet when cabinet temperature warms to preset level, adjustable in 1 C increments to -150 C.
Tissue Banking Core	Biospecimen Banking - Freezing Bath	Low temp isopentane bath	Bath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.
Tissue Banking Core	Histology/Tissue Processing - Freezing Bath	Low temp isopentane bath	Bath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.
X-ray Reconstruction of Moving Morphology Facility (XROMM)	Computed Tomography (CT) Scanner	Animage Fidex Veterinary	Veterinary CT Scanner designed for animals in the size range from rats to dogs. In vivo scanning of anesthetized animals is possible.
X-ray Reconstruction of Moving Morphology Facility (XROMM)	Videoradiography Room	Custom made biplanar	3D x-ray motion analysis methods that combine skeletal movement data from in vivo x-ray videos with skeletal morphology from 3D bone scans (e.g. computed tomography (CT) or laser scans).
X-ray Reconstruction of Moving Morphology Facility (XROMM)	X-ray Fluoroscopes	Radiological Imaging Mobile C-Arm X-ray	Two retrofitted with 30-cm image intensifiers and high-speed video cameras for measuring accurate 3D skeletal kinematics of small to medium-sized animals.

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